“Once colon cancer becomes symptomatic, nine times out of ten it is too late” (“Colon Quotes”). Colon cancer has always been an issue in the world. It is a deadly cancer that has killed many over the years. Colon cancer affects both men and women as they get older. There have been many deaths and diagnosis over the years because of colon cancer. It affects patients, families, and friends because of the battles the patients have to go through. Colon cancer is a deadly cancer that puts many through tough battles.
Colon cancer, also known as colorectal cancer, is found all around the world. It is most common in North America and Europe and is least rare in Asia and Africa (Garnick 786). This shows how colon cancer is known all over the world. It also shows how location and culture affects the chances of someone getting colon cancer. Worldwide, the incidence of colon cancer in developed countries is 37 (per 100,000 people per year) and in undeveloped countries, 10 (Panno 58). This proves that colon cancer is more common in developed countries because there are more choices and a bigger variety of food. This also proves that where someone lives in the world could affect their chance of getting colon cancer. There is a lot of information, cases, and facts about colon cancer. The annual number of new colon cancer cases worldwide is 164,673 in North America, 41,946 in South America, 362,710 in Europe, 23,454 in Africa, and 338,832 in Asia (Panno 56).
There are many different parts to the digestive system, including the colon. The colon, also known as the large intestine, is an important part of the body. “The colon and rectum are parts of the digestive system, which is also called the gastrointestinal (GI) system…” (“Co...
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Panno, Joseph. Cancer: The Role of Genes, Lifestyle, and Environment. New York: Facts On File, 2005. Print.
Cancer is one of the 9 National Health Priority Areas (NHPA), areas which account for a significant portion of the burden of disease, but have sizeable potential for improvement. In Australia, CRC is the second most common cancer, after prostate (in men) and breast cancer (in women) (AIHW, Cancer incidence projections). The incidence has gradually increased (by 13% in males from 1982-2007) (AIHW, Cancer in Australia an overview). This is compounded by the ageing population and population growth, with 14,860 new cases in 2010 (http://www.cancer.org.au/about-cancer/types-of-cancer/bowel-cancer). This graph demonstrates this upward trend ((AIHW, Cancer incidence projections):
Colorectal cancer, or CRC, affects African American men and women more than Caucasians, at a rate 20% higher. This is concerning when faced with the mortality rates among African Americans, 28% higher for women and 14% higher for men than for Whites. African Americans are also more likely to be in later stages of the disease when diagnosed. There is a need to study and evaluate why these factors exist, as proper screening and early diagnosis can severely impact survival rates for CRC. One study attempts to find the solution through testing, however, this study slightly discredits itself along the way.
Colon cancer is the third most common cancer in men and women, responsible for more than 57,000 deaths in 2001 alone. Colon polyps, which can lead to colon cancer, are found in about 30-40% of people aged 60 or older- and the risks of polyps increase with age” (Lerche Davis, 2003). Most cases of colon cancer start as small adenomatous polyps. Many people experience no signs or symptoms in the early stages of colon cancer. Some signs and symptoms can include diarrhea, constipation, or any change in consistency of your stool that continues for longer than a month. Any bleeding from the rectum or blood found in the stool can also be a sign of colon cancer. Continuing abdominal pain, cramps, gas, weakness, fatigue and unexplained weight loss could all be signs of rectal cancer in the patient (Staff,
Colon cancer is a deadly cancer but sometimes you can survive through it if you find out sooner that you are diagnosed with colon cancer. People that are older than 50 are usually diagnosed with colon cancer. Colon cancer can spread different part of your body and cause you a lot of pain. Doctors have found some treatments to fix colon cancer but when you are on stage three or four sometimes there is nothing that they can do. Doctors are working hard to find new treatments and maybe someday colon cancer would not be a cancer that can kill you anymore.
The patients in the Chen, et al., 2003 study suffered from damaged colonic epithelium because of “elevated levels of reactive oxygen species (ROS) and reduced oxidative defenses” (Chen et al., 2003). ROS are chemical species containing oxygen. This is another cause of genomic instability, in turn, this will lead to tumor formation and progression. Not only did the reactive oxygen species cause damage to the colonic epithelium but it also induces genetic damage to the DNA. The DNA received acute damage from base alterations, abasic sites, and strand breaks.
Dr. Wendy Garrett’s talk on the gut microbiome and its connection to disease, and more specifically colon cancer, can be connected to the Darwin’s Theory of Evolution. The variation that lies among the populations of bacteria that live amongst our human cells is tremendous and has evolved to a point of significant diversity. Specifically, the bacteria that lives in our guts has nine different divisions of bacteria. This can be compared to the ocean, which has twelve divisions, and soil, which generally has around twenty. Our gut microbiome provides 10% of our caloric intake, aids in the production of vitamin B, K, biotin, folic acid, and thiamine, and protects our bodies from pathogens. The human body allows for many opportunities for exploitation.
“Since 1990, over 6 million Americans have died of cancer, more than the combined casualties from the Civil war, WWII, and the Vietnam and Korean conflicts combined” (Faguet, p. 5). According to American Cancer Society projections, there were 1,529,560 new cases of cancer in 2010. Cancer is becoming more and more common around the world. New cancers are constantly being discovered. Researchers are finding new ways to detect cancer and treat it so that the fatality rate does not rise. However, there are some cancers that researchers have not yet discovered a cure for. It is very important for Cancer Research to continue so that one day these cancers will no longer be a treat.
How could your gut bacteria cause you colon cancer? According to the article, “Gut Microbes Combine to cause Colon Cancer, Study Suggests” They reported that there is two type of bacteria causing colon cancer according to recent research publications. There are two type of bacteria associated with colon cancer Bacteroides fragilis and E. coli, they are known to produce a layer in the intestine lining. According to this article, E. coli have toxin that can damage DNA of the colon cells. Additionally, B. fragilis produce another toxin that damage the DNA and inflames the cells. There bacteria are not common to everyone, but some people have them in their intestine. In their study, these toxins expel from bacteria cause cancer when put into mice.
Colon and rectal cancer develop in the digestive tract, which is also called the gastrointestinal, or GI, tract. The digestive system processes food for energy and rids the body of solid waste matter (fecal matter or stool). Colon cancer and rectal cancer have many features in common. Sometimes they are referred to together as colorectal cancer.
Colon Cancer would have to be one of the many cancers that Americans suffer today in the twenty-first century. Not only are Americans suffering form Colon cancer, but everyone in the whole world as well. It is the third most commonly diagnosed cancer and the second leading cause of cancer death in men and women combined in the US according to Colon Cancer Alliance. Just in the USA The American Cancer Society estimates 136,830 people will be diagnosed in 2014 and 50,310 will die from colon cancer in the United States. That is an unbelievable large amount of people dying because of this cancer. Colon cancer is also known as Colorectal cancer, this process occurs in the rectum/colon area. It starts in the large intestine, the lower part of your digestive system. Most of colon cancers develop first as colorectal polyps, which are abnormal growths inside the colon that can maybe turn cancerous.
Colon cancer is the second leading cause of cancer death in the United States. Every four minutes a person is diagnosed and every nine minutes someone dies. People with a first-degree relative such as a parent, sibling, or child who has colon cancer are between two to three times more the risk of developing the cancer than those without a family history. The five- year survival rate for colon cancer found at a local stage is 90%. The five- year survival rate for colon cancer at the regional stage is 70%. The five- year survival rate for colon cancer found at the distant stage is 12%. Ninety % of new cases and 95% of deaths from colon cancer are in people 50 years of age or older. Colon Cancer has many symptoms, stages, and also treatments. (Roger W. Harms)
CANCER is a medical term to describe an abnormal growth of cells. Abnormal cells that are able to grow and divide, but unable to die as normal cells do. COLON is a medical term for the large intestine. Together COLON CANCER is a disease used to simply state an abnormality of cell growth within the large intestine. Colon cancer has contributing risk factors, preventative factors, symptoms and various treatments/solutions according to the individual’s diagnosis.
Everyone is born with certain genetic mutations that make the them more likely to develop cancer in a later time in life. Though they might have a genetic feature, cancer will not develop unless triggered by environmental factors such as air and water pollution. As a matter of fact, my grandfather started smoking alongside consuming heavy amounts of alcohol around the age of 15, smoking and heavy alcohol intake have been considered as one of the potential causes of colon
Colon cancer is a cancer of large intestine (colon), the lower part of your digestive system. Rectal cancer is cancer of the last several inches of the colon. The type of colon cancer is adenocarcinomas.
Literature review is carried on by using California Health Surveys and other research articles were chosen regarding disparities in colon cancer screening among Asian Americans. These articles were obtained by using literature search engines such as PubMed, Medline, EMBASE, Health Policy reference center, EBSCO and others. Key words used for searching articles were colorectal cancer, colon cancer, Asian, Asian American, South Asians, screening, etc. Articles with relevant studies were derived from these databases and only full papers published in English were included. Cancer statistics were retrieved from the World Health Statistics of the World Health Organizations database, California Cancer Registry data, and Center of Disease control and