Click Chemistry Reaction Types Essay

No Works Cited
Length: 951 words (2.7 double-spaced pages)
Rating: Yellow      
Open Document

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Click chemistry was created by taking cues from how nature naturally reacts. 1 The goal of Sharpless and colleagues was to create a number of selective blocks that could be connected in many different ways with the ability to work in many various applications. 1 For a reaction to be defined as click chemistry: “the reaction must be modular, wide in scope, give very high yields, and generate only inoffensive by products that can be easily removed” and it must have undemanding reaction conditions. 1 The high thermodynamic driving force of the click reaction is the reason click reactions are able to achieve their specified characteristics.1 High selectivity for a lone product and a rapid completion of the reaction is another feature of click reactions. 1 The formation of carbon-heteroatom bond reactions cover the majority of examples of click chemistry including cycloadditons of unstaturated species nucleophilic substitution reactions, non-aldol carbonyl chemistry , and addition carbon-carbon multiple bonds. 1
There are more than one click chemistry reaction types. There’s the nucleophilic opening of rings, cycloaddition reactions, and protecting group reactions. 1

There are various examples of click chemistry being coupled with controlled radical polymerization.
Three common controlled free radical polymerizations are: atom transfer readical polymerization (ATRP), nitroxide-mediated polymerization (NMP), and reversible-addition fragmentation chain transfer (RAFT) polymerization.3 Click chemistry featuring the cycloaddtion of azide and terminal alkynes catalyzed by copper (I) were made popular by Sharpless.3 These reactions are very efficient and practical . The product of 1,2,3 triazole is very stable chemically. 3 The...

... middle of paper ...

...monomers including: various polyacylates, polystyrene, polymethacrylates, polyacrylnitrile, and polyethylene nitriles, and more. 5 The method for using ATRP with click chemistry is as follows: using alkyl- telechelic macromonomers, b) using azido-telechelic macromonomers, and c) using acetylenic or azido sidechain moeites. 4 Resource 4- Matyjaszewski and coworkers28 “ using a reaction between pendant nitrile moieties and sodium azide.(Scheme 3) used a type of Huisgen 1-3 dipolar cycloaddtion reaction to fix the azide group onto the sidechains of polyacrylonitrile or to polyacrylonitrile block copolymers using ATRP. The addition of the azide anion was catalyzed by using SnCl2 or ZnCl2 to create a tetrazole. The side chain modified polymers were then were then placed in a azide/alkyne click reaction using 3-azidopropyl methacrylate as the monomer (scheme 7 source4)>

Click the button above to view the complete essay, speech, term paper, or research paper

Need Writing Help?

Get feedback on grammar, clarity, concision and logic instantly.

Check your paper »

This essay is 100% guaranteed.

Title Length Color Rating  
Essay on History of Chemistry: Chemical Weapons - ... Next is Nerve Agents, which are considered to be organophosphates. Nerve agents work by stopping flow of ACh, which is responsible of muscle contraction. When effected it leaves you with no control of your body, leading you to a slow painful death. Then, there is Blood Agents. Blood Agents are fast acting, cyanide or arsenic type of positions. They work quickly and go into your bloodstream. At short term exposures it can just cause dizziness and nausea. But long term can cause brain damage and muscle paralysis....   [tags: chemistry, technology, victims, types] 798 words
(2.3 pages)
Better Essays [preview]
Essay about Chemistry Report: Experiment on Rates of Reaction - Rates of Reaction CaCO3 + 2HCl → CaCl2 + H2O + CO2 In this report I will be suggesting my predictions on what the rates of reaction will be and what the actual rates of reaction are. I will do this by collecting data from experiments and I will show this by putting data into a table. The main aim of my experiment is to find the rate of reaction over time taken and the rate of reaction when the concentration of hydrochloric acid increases or decreases. I will try to make my experiment as accurate as I can....   [tags: chemistry experiment, lab report] 3714 words
(10.6 pages)
Powerful Essays [preview]
Essay Nuclear Chemistry - Types of Radiation: • List the three types of Radiation and describe conditions under which each case occurs. Alpha, Beta, Gamma. Alpha radiation/emission - Alpha particles are the nuclei of a Helium atom 42He. Consisting of two protons and two neutrons, positively charged. The nuclei are ejected from heavy, unstable nuclei so as to remove excess protons and neutrons. However, the formed nuclei may still be radioactive in which even further decay will occur. Alpha emissions occur in nuclei with atomic numbers greater than 83....   [tags: Chemistry]
:: 4 Works Cited
1999 words
(5.7 pages)
Term Papers [preview]
Surface Chemistry of Silica Essay - In order to gain strong insight into the surface chemistry of silica we have perform a thorough literature search. Our goal is to identify the pioneer research performed on silica and silica supported catalyst. Particular interest lies in silica-water-cobalt and silica-alcohol-cobalt systems. This study is both on macro and micro level so that a complete theoretical base can be established. From this theoretical knowledge, key areas to look upon will be identified and a design of experiments will be established....   [tags: Chemistry] 1273 words
(3.6 pages)
Strong Essays [preview]
Chemistry before Technology: Alchemy Essay - ... According to the New York Times article “The Magical Origins of Modern Chemistry” alchemy was a philosophy and practice that sought to understand the nature of matter. Because of the alchemist they were able to make porcelain, pigments, perfumes, gunpowder, and pharmaceuticals. Before technology was brought into chemistry it took longer for scientist to discover certain items and chemical compounds and it took them longer to figure out how to do certain things. Before there were phones and computers scientist and chemists could not share their data with others in hope to gain more knowledge and ideas on how to make chemical reactions work....   [tags: history of chemistry, medical research] 800 words
(2.3 pages)
Better Essays [preview]
The Click Click Click of the Metronome Essay - For the past five years, perhaps longer, the only things I hear are my own raspy breaths and a constant, monotonous, clicking noise. That, and the walls of my box, are enough to drive anyone past the brink of sanity. For me, it already has. I live in a box. Twenty feet high, twenty feet long, twenty feet wide. A perfect cube. The floor, ceiling, and walls are covered with one long, continuous mirror, replicating itself and every one of my miniscule movements. Not only that, but it seems like I am suspended in space: The mirrors reflect the other mirrors, which reflect other mirrors, creating an endless cycle and infinite passageways that always have a solid door....   [tags: short story] 758 words
(2.2 pages)
Strong Essays [preview]
Essay on Equilibrium Reaction Lab - IBDP Chemistry IA: Equilibrium Reaction Lab Introduction: Reactions are based on collisions of particles, in which the particles must have sufficient energy. Some chemical reactions are reversible, and when the rate of the forward reaction equals the rate of the reverse reaction, the process has reached equilibrium. As it will appear to have stopped, as there is no overall change due to the rates being equal. Through this lab, we will be investigating one factor that will affect the equilibrium constant....   [tags: Chemistry, Collision of Particles, Reactions]
:: 7 Works Cited
1329 words
(3.8 pages)
Strong Essays [preview]
Chemistry Investigation on Neutralisation Reaction Essay - Chemistry Investigation on Neutralisation Reaction Plan Neutralisation is the reaction that occurs when an acid has its acidity, that is its hydrogen ions removed by, another chemical containing OH- hydroxide ions. Chemicals that can cancel out an acid in this way are: bases (metal oxides or hydroxides), alkalis (bases that dissolve), metals (e.g. magnesium) or metal carbonates (e.g. marble chips) All of these have a similar way of removing the hydrogen from the acids (they swap it or their metal atoms) but the reactions are quite different....   [tags: Papers] 2294 words
(6.6 pages)
Strong Essays [preview]
Chemistry and Synaptic Transmitters Essay - Chemistry and Synaptic Transmitters The most common psychoactive substances can be divided into depressants (i.e., alcohol, sedatives, hypnotics), stimulants (i.e., cocaine, amphetamines, ecstasy), opioids (i.e., morphine and heroine), and hallucinogens (i.e., PCP, LSD, cannabis). The brain has different effects to different psychoactive substances. They bind to different receptor types, and can increase or decrease the activity of neurons through several different mechanisms. Consequently, these psychoactive substances have different behavioral effects, different rates of development of tolerance, different withdrawal symptoms, and different short-term and long-term effec...   [tags: Chemistry Science Scientific Essays]
:: 7 Works Cited
1653 words
(4.7 pages)
Strong Essays [preview]
Organic Chemistry Essay - Chemistry has been called the science of what things are. Its intent is the exploration of the nature of the materials that fabricate our physical environment, why they hold the different properties that depict them, how their atomic structure may be fathomed, and how they may be manipulated and changed. Although organic reactions have been conducted by man since the discovery of fire, the science of Organic chemistry did not develop until the turn of the eighteenth century, mainly in France at first, then in Germany, later on in England....   [tags: Chemistry] 1119 words
(3.2 pages)
Strong Essays [preview]