Essay on Chronic Obstructive Pulmonary Disease: Nebulized Furosemide

Essay on Chronic Obstructive Pulmonary Disease: Nebulized Furosemide

Length: 1476 words (4.2 double-spaced pages)

Rating: Powerful Essays

Open Document

Essay Preview

COPD is noted as being the fourth leading cause of mortality in the United States. Mortality is expected to increase among COPD patients despite advances in its management. As exacerbations and hospitalizations characterize a key driver of the cost and morbidity of COPD, significance should be placed on interventions aimed at delaying the advancement of disease, inhibiting exacerbations, and reducing the risk of co-morbidities. Treatment for COPD has been at of a standstill in recent years. Beta2 antagonists, corticosteroids, and theophylline have been at the helm. However, nebulized furosemide has pushed its way from the background into the forefront recently.
A major cause of disability and anxiety, dyspnea is the most prominent symptom of COPD and COPD exacerbations and is the reason most patients seek medical attention. The stimulation of slowly adapting stretch receptors (SARs) most likely decreases the feelings of dyspnea. It has been hypothesized that inhaled furosemide acts indirectly on sensory receptors to relieve dyspnea.
It is possible that the alleviation of dyspnea with inhaled furosemide could also be related to increased slow-adapting receptors (SAR) activity. Studies have shown that inhaled furosemide both sensitized SARs and desensitized rapid-adapting receptors (RARs). The relief of dyspnea with inhaled furosemide could be partially related to the reduced activity of RARs, which are pulmonary irritant receptors. Because patients with severe COPD cannot sustain bronchodilation, increasing blood flow to poorly ventilated lung areas causes a ventilation-perfusion mismatch. Nebulized furosemide reverses the pathological process by improving ventilation.
The improvement of the FEV1 measurement after t...


... middle of paper ...


...Effectiveness of influenza vaccination: a randomized controlled study.Chest. 2004;125(6):2011-20.
10. Niederman MS. Introduction: COPD--the role of infection.Chest. 1997;112(6 Suppl):301S-302S.
11. Nishino T. Dyspnoea: underlying mechanisms and treatment.Br J Anaesth. 2011;106(4):463-74.
12. Moosavi SH, Golestanian E, Binks AP, Lansing RW, Brown R, Banzett RB. Hypoxic and hypercapnic drives to breathe generate equivalent levels of air hunger in humans.J Appl Physiol. 2003;94(1):141-54.
13. Sharp JT. Therapeutic considerations in respiratory muscle function.Chest.1985;88(2 Suppl):118S-123S.
14. Orozco-Levi M. Structure and function of the respiratory muscles in patients with COPD: impairment or adaptation?. European Respiratory Journal. 2003;22(Supplement 46):41s-51s.
15. Lundsgaard C. Studies on cyanosis : I. Primary causes of cyanosis.J Exp Med. 1919;30(3):259-69.

Need Writing Help?

Get feedback on grammar, clarity, concision and logic instantly.

Check your paper »

Analysis Of Laboratory Data And Diagnostic Tests Essay

- Analysis of Laboratory Data and Diagnostic Tests Electrolytes On admission (9/8) patient had a high CO2 value of 34 mEq/L due to her COPD exacerbation. With therapeutic management as described in the next section her CO2 value was reduced to 32 mEq/L on 9/12, and brought to withing normal limits on 9/13 with a value of 29 mEq/L. Potassium and sodium levels were decreasing due to the use of dieurteics, although they are still within normal limits. Chloride was also just below the normal range on admission, likely due to a combination of heart failure, and respiratory acidosis related to her COPD....   [tags: Asthma, Chronic obstructive pulmonary disease]

Powerful Essays
1114 words (3.2 pages)

Chronic Obstructive Pulmonary Disease Essay

- Chronic Obstructive Pulmonary Disease refers to a group of lung diseases that block airflow and make breathing difficult. COPD is a progressive lung disease that makes it difficult to breathe. Approximately 12 million people in the United States have been diagnosed and many more may be affected and not know that they have it. WWW.healthline.com/health/COPD. There are two airway obstruction diseases associated with COPD; emphysema and chronic bronchitis. Emphysema, a type of COPD, involves the damage to the alveoli (air sacs) in the lungs, due to the loss of lung elasticity and hyperinflation of the lung....   [tags: Chronic obstructive pulmonary disease, Pneumonia]

Powerful Essays
2036 words (5.8 pages)

Essay on Chronic Obstructive Pulmonary Disease

- Chronic Obstructive Pulmonary Disease Pathology 1321.001 Christopher Hall 11-19-15 Chronic Obstructive Pulmonary Disease, also known as COPD, is defined as a progressive, chronic lung disease that makes it difficult to breathe by limiting airflow and it is characterized by chronic inflammation of the airway and shortness of breath and wheezing. Progressive meaning that the disease gets worse over time. Chronic Obstructive Pulmonary Disease is one of many diseases that leads to restrictions, some type of disability, and also an increase in the mortality in the elderly population....   [tags: Chronic obstructive pulmonary disease, Asthma]

Powerful Essays
1324 words (3.8 pages)

Chronic Obstructive Pulmonary Disease ( Copd ) Essay example

- Chronic Obstructive Pulmonary Disease is an incapacitating condition that can severely alter even the basic day to day activities. COPD is a progressive disease, which means it worsens over time. The key feature of this disease is that it makes it hard to breathe. There are many medical and dental considerations to look at when seeing a patient with this disease. It is important to understand how the lungs work to understand how COPD affects someone. When a person breathes the air goes down your windpipe or trachea and into your bronchial tubes....   [tags: Asthma, Chronic obstructive pulmonary disease]

Powerful Essays
1308 words (3.7 pages)

Chronic Obstructive Pulmonary Disease ( Copd ) Essay

- INTRODUCTION Emphysema is the main type of chronic obstructive pulmonary disease (COPD). It is a long-term, irreversible yet preventable disease in which the walls of the alveoli become inflamed and lose elasticity causing the bronchioles to collapse. As a result of the inflammation, air becomes trapped in the alveoli which become hyperinflated, and may rupture – creating one larger air space instead of many small ones – which decreases the surface area of the lungs and, in turn, the amount of oxygen that reaches the bloodstream, causing an inability to breathe normally....   [tags: Chronic obstructive pulmonary disease, Asthma]

Powerful Essays
986 words (2.8 pages)

Essay on Chronic Obstructive Pulmonary Disease ( Copd )

- Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease, or COPD, is not just one specific disease. It is actually a group of diseases common to the lungs that make it difficult to breathe normally and also blocks airflow. It most commonly stems from smoking tobacco, but has been linked with inhaling fumes from cooking and heating in a home that has not been vented correctly. In rare instances, COPD can be caused from Alpha-1-antitrypsin deficiency, which is a genetic disorder where your body does not have enough of the protein Alpha-1-antitrypsin....   [tags: Chronic obstructive pulmonary disease, Asthma]

Powerful Essays
1279 words (3.7 pages)

Chronic Obstructive Pulmonary Disease ( Copd ) Essay

- Chronic Obstructive Pulmonary Disease “COPD affects 24 million Americans and reaches people in all the 50 states” (COPD statistics across America). What exactly is this disease that is affecting so many people across the United States. It’s chronic obstructive pulmonary disease, or COPD. COPD is described almost exactly as it sounds. It is a chronic disease that obstructs breathing, making it difficult to breathe. According to Mayo clinic staff, it is defined as a chronic inflammatory lung disease that causes obstructed airflow from the lungs....   [tags: Asthma, Chronic obstructive pulmonary disease]

Powerful Essays
920 words (2.6 pages)

Chronic Obstructive Pulmonary Disease ( Copd ) Essay

- Chronic obstructive pulmonary disease or COPD is a group of progressive lung diseases that block airflow and make it hard to breathe. Emphysema and chronic bronchitis are the most common types of COPD (Ignatavicius & Workman, 2016, p 557). Primary symptoms include coughing, mucus, chest pain, shortness of breath, and wheezing (Ignatavicius & Workman, 2016, p.557). COPD develops slowly and worsens over time if not treated during early stages. The disease has no cure, but medication and disease management can slow its progress and make one feel better (NIH, 2013) The principle cause of the COPD is long-term exposure to harmful airborne chemicals and particles....   [tags: Chronic obstructive pulmonary disease, Pneumonia]

Powerful Essays
903 words (2.6 pages)

Chronic Obstructive Pulmonary Disease ( Copd ) Essay

- According to World Health Organization “Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by chronic obstruction of lung airflow that interferes with normal breathing and is not fully reversible. The more familiar terms 'chronic bronchitis ' and 'emphysema ' are no longer used, but are now included within the COPD diagnosis”. The disease can be tested by a simple test called spirometry. Spirometry measures how deep and how fast air can move in and out of the person’s lungs....   [tags: Chronic obstructive pulmonary disease, Asthma]

Powerful Essays
729 words (2.1 pages)

Chronic Obstructive Pulmonary Disease ( Copd ) Essay

- Chronic Obstructive Pulmonary Disease or (COPD) is a common chronic inflammatory lung disease that restricts airflow from the lungs. People with COPD have a high risk of obtaining the condition. The symptoms you can develop from this disease are ass follows; trouble with breathing, chronic coughing, wheezing, weight loss, morning headaches, and swollen feet or ankles. There are two common conditions that contribute to this disease; these are emphysema and chronic bronchitis. Emphysema is a condition in where the alveoli at the end of the bronchioles of the lungs can be destroyed as a result of the damaging exposure....   [tags: Asthma, Chronic obstructive pulmonary disease]

Powerful Essays
716 words (2 pages)