Chlamydia And Pelvic Inflammatory Disease

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Chlamydia and Pelvic Inflammatory disease (PID) are very common sexually transmitted infection and disease respectively. This paper is about finding the correlation between chlamydia and pelvic inflammatory disease and how factors like age, socioeconomic conditions, medical facilities, variants of same bacteria can alter the results of progression from chlamydia to PID found in same population under study. Untreated chlamydia can cause more serious medical conditions like PID, infertility and ectopic pregnancy.
Pelvic Inflammatory Disease is the most common sexually transmitted disease found mostly in women. It is also one of the main cause of infertility in women. Chlamydia is also a sexually transmitted infection which is caused by bacteria- Chlamydia trachomatis. Exposure to chlamydial infection can lead to higher risk of pelvic inflammatory disease. These both sexually transmitted diseases show different symptoms but they are considered to be interconnected. Chlamydial infection, which most of the times show very slow or no symptoms, if left untreated can lead to pelvic inflammatory disease and can further cause infertility.
To determine the correlation of chlamydia and pelvic inflammatory disease, microRNA were used as biomarkers in an experiment for the diagnosis of bacterial growth infection. These microRNA regulate chemokine cytokine responses which are the immune responses that take place during bacterial infections. In a study of two chlamydial variants of C. muridarum – CmVar001 and CmVar004 (Chlamydia muridarum is also one strain of bacteria which cause chlamydia) the microRNA expression showed by these bacterial variants was examined. The experiment was done in vitro and in vivo. In vitro, the growth of variants was d...

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...l play important role in progression of infection in women. These are some of the factors that are related to women but there are also different variants of bacterial strains that are capable of growing at different rates in women’s body. Some variants grow rapidly than others. This growth rate influences the progression of disease. The focus of this paper is on the effects of C. trachomatis on upper genital of women but in one of the experiments, it was also seen that more women were hospitalized for PID who were previously infected with gonorrhea. Chlamydia is one of the causes of PID if left untreated but there are other sexually transmitted infections also that can lead to this disease. It also depend on the health, age, previous condition of pregnancies and abortions, accessibility to medical facilities that affect the progression or regression of infections.

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