Biology Coursework: Improving Trauma Treatment Through EPR Essay

Biology Coursework: Improving Trauma Treatment Through EPR Essay

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Biology Coursework: Improving Trauma Treatment Through EPR

Identify a problem.

Trauma pateints are those who have suffered serious and life threatening injuries. First response teams have little time to stabilise their condition and attempt to save their life. Whilst surgeons and doctors have the technology, skills and knowledge to be able to save victims of blunt or penetrating trauma, they have very limited time in which to do it. “The Golden Hour” is the time period from the injury of the patient in which appropriate medical treatment will prevent death. However, this “Golden hour” can be anything from minutes to the hour, giving medics very little to work with.

Describe/Explain methods to solve this problem.

Recently there have been large leaps in trauma medicine, and this time frame has been extended. One method which is being researched is that of EPR, Emergency Prevention and Resuscitation. This is in effect a form of suspended animation. The patient’s heart is stopped, and the body cooled to below 10°C by flushing the circulatory system with a chilled saline solution, at which point the patient has no brain activity or pulse. These extreme temperatures greatly reduce the body’s requirement for oxygen, allowing cells to continue to live without the patient breathing or having a heartbeat. This lack of circulation and metabolism allows doctors and surgeons to repair any serious injuries and greatly increase the patient’s chance of survival. Once the patient has been patched up they are revived by transfusing warm blood back into the body and sometimes using an electrical shock to restart the heart.

So far this method has only been tested on pigs and dogs, with great success, (Experimental r...

... middle of paper ...

... than when using the Minimal Fluid Resuscitation method, particularly when the method was used with mild hypothermia, which involves using cooled fluids, usually to around 30-34⁰C.

Quote experiments/results?-Rosie Connolly 3/7/10 10:07 AM


Safar Centre for Resuscitation Research

Research projects, papers, etc.

Worldwide recognised.

Access to research papers – does this count as paper based even though I’ve found them online?

US government Clinical Trials service.

Information on the human trials in EPR.

New scientist article reporting first breakthroughs with mice.


Evaluate source.

Article ?

References to surgeons, research papers and trials.

Biased – part of Pittsburgh Uni, the centre of the trials.

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