Basal Cell Carcinoma:
Basal cell carcinoma is a mass of cells that has grown in an abnormal and uncontrollable manner. These cells clump together to form a tumour, which is a malignant cancer. It is thee most common type of skin cancer and it can be characterised as a “slow-growing” cancer that rarely spreads to neighbouring sites to form more malignancies (Kumar et al., 2012:864).
Epidemiological Information:
A person who has made contact with the sun is at risk of developing this type of skin cancer. Generally people with lighter coloured skin are more susceptible of developing this skin cancer than people who are darker skinned. People with lighter coloured eyes also have a greater chance of developing this skin cancer. Basal cell carcinoma is more likely to be seen in older people and it is fairly rare to be seen in children (SkinCancer, 2014).
What causes cells to become cancerous?
Mutations occur in the normal cells which cause them to multiply rapidly, grow abnormally and uncontrollably. These cells clump together in a mass to form a tumour. These tumours are not necessarily malignant; they only become malignant once they invade other tissues. Due to invasion, they accumulate space and feed off the nutrients used to supply the local space. The nutrients aid them in survival and functioning (Patient, 2014).
Pathogenesis of Basal Cell Carcinoma:
Basal cell carcinoma is a result of the exposure to ultraviolet light. Prolonged exposure leads to a greater chance of developing this skin cancer, as the ultraviolet rays cause a mutation in the tumour suppressor gene to arise (Crowson, 2006, Carucci & Leffell. 2008, Miller, 1991a,b cited by Khalifa & Adil, 2012:43). A number of subtypes of basal cell carcinoma are able to become ...
... middle of paper ...
...in is exposed to. You could apply sunscreen to areas of your body that is most likely to be exposed to the sun, such as your face, neck and forearms. By all means avoid tanning salons. Do not all your skin to burn if you are outside for long periods of time. Always do a self examination of your skin every month. If you suspect something, always act on it and seek medical attention from your dermatologist.
Basal cell carcinoma can be treated or removed in a number of ways, but Mohs surgery has been accepted as the most effective way to eradicate the disease and reoccurring tumours. The process involves removing a very thin layer of tumour and then examining it immediately under the microscope. If tumour cells are found in the layer, another layer is removed and examined until enough layers have been removed and examined, to display no signs of the malignancy.
Skin cancer is a significant public health issue in Australia. Exposure to ultraviolet radiation emitted by the sun in the UVA and UVB wavelengths is the primary cause. Australia has been a world leader in efforts to protect the ozone layer, the main line of defense against ultraviolet radiation emitted by the sun. Ultraviolet radiation induces the formation of thymine dimers that cause mutation of skin cells if not repaired before DNA replication. Mutations of tumor suppressor genes can lead to uncontrolled cell growth. Ultraviolet radiation also causes immunosuppresion that allows skin cancers to become established. Basal cell carcinoma, squamous cell carcinoma, and melanoma are types of skin cancer caused by sun exposure, though each form is associated with a different pattern of exposure. Australia has the highest rate of skin cancer in the world, due to a combination of tropical latitude, fair-skinned population, outdoor lifestyle, and high amount of ambient ultraviolet radiation. Widespread opinions about tanning and health benefits of sunlight lead many Australians to intentionally overexpose themselves to the sun. State cancer councils have developed sun safety and awareness campaigns, such as “Slip! Slop! Slap!” and “SunSmart,” to educate the population about sun exposure and encourage early detection of skin cancers. Gradual changes in knowledge and behavior indicate that the fight against skin cancer can be won.
What is skin cancer ? first, Skin is the largest organ of the body . it gives our body protection from harms, injuries and infections. It also organize the body temperature and dispose of waste substances through the glands . out layer of the skin is called the epidermis and the layer underneath is known as the dermis . Skin cancer is type of disease where malignant cancer cells are to be found the outer layer of a person's skin and is the uncontrolled development of the irregular skin cells .It occurs when unrepaired DNA damage to skin cells caused by ultraviolet radiation from sunlight or genetic defects, that lead the skin cells to duplicate rapidly and form malignant tumors. there are three main types of skin cancer which are basal
When people are exposed to UV light, from the sun or, for example, in a tanning booth, the melanocyte cells make more melanin and pack together tighter, resulting in darker skin tones. If the skin is receiving too much ultraviolet light, the melanocytes may begin to grow abnormally and become melanoma during this process.
In today’s culture, being tan coincides with what is believed to be beautiful. As a result, it is no surprise that in the United States of America, an estimated 922,000 people are currently living with some level of melanoma. Even though the news media and doctors warn people about the risks of too much sun exposure and give information as to how to prevent contracting skin cancer, people are still disregarding this important information and going into the sun for extended periods of time unprotected.
Basal Cell Carcinoma often abbreviated as (BCC) is the most frequently appearing form of skin cancer. They are also referred to as Basal Cell Cancer. It was discovered along the way as skin cancer was being treated as different types with no specific period. The BCCs’ are uncontrolled growths that normally arise in the skin’s basal cells. These cells lie in the deepest layer of the epidermis which is the outermost layer of the skin. BCC’s are normally caused by a combination of two things; one is cumulative UV exposure and the other is intense occasional UV exposure. The most vulnerable, according to a research done, tend to be people with fair hair, blue eyes and fair skin and this is because they tend to burn easily. The BCCs’ may first appear as a small white flesh or a colored bump that may bleed. Other normal appearances may look like open sores, red patches on the skin, pink growths, shiny bumps or scars. 80% of Basal Cell Carcinoma cases are mainly found in the head and neck that is the body parts that are mainly exposed to the sun. The nose also tends to be most vulnerable and according to a recent study done, 40% of BCC that were diagnosed on the head and neck were adjacent to the nose.
Sun shine contain ultraviolet ray which can cause the sunburn or even skin cancer. According to Cancer Council in Australia, Australia has highest incident rate of skin cancer in the world. More than 430000 Australians are diagnosed with skin cancer each year. There are approximately 60 percent of people who have got skin cancer will survive greater than five years after they diagnosis (Cancer Council Australia, 2014). In order to protect people under the sun, the sun protective behaviour is significant necessary.
The most common type of skin cancer is nonmelanoma skin cancer, which is classified as basal cell carcinoma or squamous cell carcinoma. “These begin either in the basal cells or squamous cells that are located at the base of the outer layer of the skin.” (Kenneth, 2012) Basal and squamous cell cancers are among the less serious types of skin cancers, but make up ninety-five percent of all skin cancers.
Basal and squamous cell skin cancer are the most common forms of skin cancer. Multiple studies have shown that these cancers are almost always connected to large amounts of sun exposure. This can come from things like outdoor sports, performing something outdoors with little coverage from clothing, and getting multiple severe sunburns. You can see signs of skin cancer inside and outside of your body. Rough, thick, dry skin patches are common symptoms, but things
Tumors are formed by the alteration of the body’s own cells. This can be caused by environmental factors such as radiation, like UV exposure, chemicals or viruses 1. These can disrupt genes that control growth and cause an increase in cell division and proliferation. Proto-oncogenes are those genes that control normal but essential cell processes that keep cell growth and death in check. Two important categories are apoptosis genes, which regulate cell death, and tumor suppressor genes, which decrease cell propagation 1 . If these genes were mutated to the point where they cannot produce a functioning protein, cell division would continue far past what it was supposed to and unhealthy cells would be allowed to live and continue to multiply. This is what creates a malignant tumor. Certain conditions in the body can also promote the growth of cancer cells. One of these is a deficiency of natural killer (NK) cells, which are able to kill cancer cells by creating a pore in the cell membrane with perforin and releasing granzymes into the cell. Low levels of perforin allow for tumor growth 1. Chronic inflammation can also ...
amount of UV exposure absorbed by a person is a direct result of the intensity of the light absorbed, the length of time of the exposure, and whether or not the skin was protected by clothing or sunscreen. Skin damage can be prevented by limiting when and how long one is exposed to sunlight, and by wearing protective clothing and sunscreen. Avoid exposure to sunlight during mid-day hours, when it is most intense. Tight weave clothing, and hats, protect against the sun's rays. Tanning beds, while popular, are also ...
Skin cancer is a disease where cancer (malignant) cells are found on the outer layer of the skin (epidermis). The three types of cells found in the epidermis are squamous cells, basal cells, and melanocytes. These cells in time grow to be cancerous. Thus, the three types of skin cancers are squamous cell, basal cell, and melanoma. Melanoma is the most deadliest and destructive type of cancer. (“Skin Cancer” infotrac.com) The number of people with melanoma has risen in Scotland from 3.5 in 1979 to 10.6 per 100,000 in 1998 for men and 7.0 to 13.1 for women. (Miller 945) Squamous cell and Basal cell skin cancer can kill up to 2,200 people a year in the United States. (Sommerfield SIRS.com) Basal cell, being the most common type of skin cancer, is the cancer that about 75 percent of the people have. (“Skin Cancer “ infotrac.com) Melanoma is mostly seen in older men but ever since tanning came in during the 1970’s, it has increased in women 60 percent around the ages 15-29 over the past three decades.(Sommerfield SIRS.com) “And basal cell and squamous cell cancers are increasing at a rate of about 5 percent per year”(Sommerfield SIRS.com).
The skin is the largest organ in the body, so it isn’t surprising that skin cancer is the most common of all cancers. Melanoma is the least common form of skin cancer, affecting 4% of all cases but causing 79% of skin cancer deaths. The average age of people diagnosed with Melanoma is between 45 and 55, although 25% of cases occur in people under 40. About 10% of all people with melanoma have a family history of melanoma. You are at increased risk of developing melanoma if there is a family history of melanoma in one or more of your first-degree relatives like a parent, child, brother or sister.
Cancer develops when cells in a part of the body begin to grow out of
By harnessing this normal cell process, scientists hope to have found an effective way to combat cancer. Cancer is a disease that affects human somatic cells. It causes the cells to divide uncontrollably and form masses known as tumors. There are two different types of cancer tumors. Some tumors are benign, and other tumors are malignant.
Probably the most commonly used word by your dermatologist, your beautician, your pharmacist or just the girl next door, and for a good reason. The sun’s damaging UV rays can single-handedly destroy your skin over time and in some cases even cause irreparable damage. It will burn your skin, dry it out, destroy collagen fibers and predispose you to cancer. Whether it’s a scorching sun or not, whether you are outdoors or not, sunscreen is an everyday must-wear. You have a choice.