Essay on Antibacterial Agents in the Therapy of Urinary Tract Infection

Essay on Antibacterial Agents in the Therapy of Urinary Tract Infection

Length: 1710 words (4.9 double-spaced pages)

Rating: Term Papers

Open Document

Essay Preview


1. Which antibacterial agent(s) would be effective in the therapy of Mr BT’s urinary tract infection?

Cephalexin and Gentamicin would be effective since they are equally sensitive to the pseudomonas aeruginosa microbe which implies they will kill the microbe and work against the bacteria.

2. State the mechanisms of action of each of these agents.

Cephalexin, is a beta-lactam antibiotic. The antibiotic binds to specific penicillin-binding proteins positioned inside the bacterial cell wall, this inhibits the third and last stage of bacterial cell wall synthesis. The consequences are fatal to the susceptible bacteria but comparatively harmless for the human cells because the latter does not possess such a structure. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cephalexin impedes with an autolysin inhibitor. Consequently these antibacterial drugs are bactericidal agents that impede the development of the rigid cell wall of the dividing bacteria (Neal & Michael, 2012).

Gentamicin, is a broad spectrum aminoglycoside antibiotic. Aminoglycosides such as gentamicin "irreversibly" bind to particular 30S-subunit proteins and 16S rRNA. Gentamicin particularly binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This intervenes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This area interacts with the wobble base in the anticodon of tRNA. This leads to interfering with the instigation complex, misinterpretation of mRNA so inaccurate amino acids are introduced into the polypeptide leading to non-functional or toxic peptides and the breakup of polysomes into non-functional monosomes. Gentamicin acts by...

... middle of paper ... is causing it. Giving the patient a wide-spectrum antibiotics allows the healthcare provider to treat the patient for almost any possibility until they wait for the test results to come back. When the results are receive the healthcare provider can treat the patient more specifically to the microbe (Asperheim & Mary, 2012).

Works Cited

Asperheim, & Mary, K. (2012). Introduction to pharmacology (12th ed.). St.Louis: Elsevier

Bullock, S. & Manias, E. (2011). Fundamentals of pharmacology, (6th ed.). Sydney, Pearson Education Australia.

McKenry, L.M., & Salerno, E. (2006). Mosby’s pharmacology in nursing (22nd ed.). St Louis: Mosby - Year Book, Inc.

Neal, & Michael, J. (2012). Medical pharmacology at glance, (7th ed.). Hoboken: John Wiley & Sons.

Porth, C. (2009). Pathophysiology: Concepts of altered health states (8th ed.). Philadelphia: Lippincott-Raven.

Need Writing Help?

Get feedback on grammar, clarity, concision and logic instantly.

Check your paper »

Urinary Tract Infection ( Uti ) Essay

- Urinary Tract Infection (UTI) is when bacteria gets into your urine and infects the bladder. It has caused more than 8.1 million visits to health care providers each year. About 10 in 25 women and 3 in 25 men will have symptoms of at least 1 UTI during their lifetime. The urinary tract makes and stores urine, one of the waste products of your body. Urine is made in the kidneys and travels down the ureters to the bladder. The bladder stores the urine until it is emptied through the urethra, a tube that connects the bladder to the skin, when you urinate....   [tags: Urinary tract infection, Kidney, Urine]

Term Papers
1181 words (3.4 pages)

Catheter Associated Urinary Tract Infection Essay

- Student no: 5310064 Assessment 2 Catheter associated Urinary Tract Infection Patient safety indicator Patient safety and quality care is very essential for the preventive, curative and promotive health care of the patient. Patient safety indicators are those indicators that help to provide care with patient safety. Patient safety indicators should always be measurable. There is a vital role of nurses and health care professionals in promoting and maintaining patient safety and quality care in the workplace....   [tags: Urinary tract infection, Urinary catheterization]

Term Papers
1967 words (5.6 pages)

Urinary Tract Infections : A Common Infection Essay

- Abstract A urinary tract infection is a very common infection that can happen to anybody. A urinary tract infection usually occurs when bacteria enters the urethra and multiples in the urinary system. The Urinary tract includes the kidneys, the thin tubes that carry urine from the kidneys to the bladder (ureters), and the main tube that carries the urine from the bladder (urethra). Women, men, and children are all immune to this infection. Women have the highest chances of getting it. In the Urinary tract, the main links of the ureters help get rid of any bacteria that tries to enter the urine, and the bladder helps prevent urine from backing up into the kidneys....   [tags: Urine, Urinary tract infection, Kidney]

Term Papers
1251 words (3.6 pages)

Treatment Of Urinary Tract Infections Essays

- Cephalexin is one of many western drugs that are used around the world today. Cephalexin is an “antibiotic used to treat certain infections caused by bacteria such as pneumonia and bone, ear, skin, and urinary tract infections” (Medline,2016). For a urinary tract infection, cephalexin is very safe and effective. An alternative, herbal remedy for a UTI is called Uva-Ursi or commonly known as Bearberry. UTIs are very regular and can be treated effectively with either the antibiotic or herbal remedy....   [tags: Urinary tract infection, Kidney, Urine, Bacteria]

Term Papers
1027 words (2.9 pages)

Essay on Urinary Tract Infections And The Human Body

- Urinary Tract Infection, also known as UTI, occurs in two common locations, the bladder and kidneys. The kidneys are important organs that aid in filtering out waste products from blood and maintaining water distribution throughout the body. The waste products are filtered out via bladder, which is the reason of the bladder being the second site for the infection. A normal human being has two kidneys, one on left and right side, a bean shaped organ, and is located at the back of the abdomen. “Each kidney is about 11.5 cm long, 5-7.5 cm broad, 5 cm thick, and weight about 150 grams” (HealthInfoNet, Paragraph 2)....   [tags: Urinary tract infection, Kidney, Pyelonephritis]

Term Papers
753 words (2.2 pages)

Catheter Associated Urinary Tract Infections Essay

- Catheter Associated Urinary Tract Infections I currently work on a 34 bed long-term acute care facility (LTAC) where most patients have a urinary catheter. Catheter Associated Urinary Tract Infections are something that the LTAC has dealt with over and over again. If the patients don’t have a catheter on admit; they will almost always have a catheter within a few days. The LTAC employs a quality manager that tracks catheter usage; his job is to make sure that all catheters are warranted and are out as soon as possible....   [tags: Urinary tract infection, Urinary catheterization]

Term Papers
823 words (2.4 pages)

Catheter Associated Urinary Tract Infections Essay

- “Catheter associated urinary tract infections (CAUTI), are one of the most frequently reported hospital acquired infections” (Gray, Skinner, & Kaler, 2016, p. 301). There is a growing concern over multi-drug resistance infections and how they are related to CAUTIs (Gray, Skinner, & Kaler, 2016). The implementation of a CAUTI bundle, which is a collection of 3-5 interventions, should assist in lowering the incidence of such infections (Gray, Skinner, & Kaler, 2016). The PICOT question, regarding the effect of CAUTI bundles on infection rates, will help to determine if the evidence shows that the use of the bundles can decrease the number of infections in adult patients....   [tags: Urinary tract infection, Urinary catheterization]

Term Papers
998 words (2.9 pages)

Antibiotic for Upper Respiratory Tract Infection Essay examples

- The common cold is one of the most prevalent illnesses worldwide. It is caused by a virus that inflames the membranes in the lining of the nose and throat, colds can be the result of more than 200 different viruses [10].The antibiotics don't work against any infections caused by viruses [11]. They are a powerful medicines that fight bacterial infections [12]. Antibiotics were first used to treat serious infections in the 1940s. Since then, antibiotics have saved millions of lives and transformed modern medicine....   [tags: fighting bacterial infections]

Term Papers
695 words (2 pages)

Essay about Treatment of Urinary Tract Infection

- Urinary tract infection is one of the most common infections as cited by the National Hospital Ambulatory Medical Care Survey that can affect both pediatrics and adults [4,6]. Locally, this type of infection was ranked as fourth leading cause of Morbidity in Iloilo City [15]. Such infections can be acquired either as health care associated or in the community. The cause of such infection also includes the following but not limited to poor hygiene, sex, instrumentation, anatomic structure, etc. [6]and Out of the several causative agents, Escherichia coli and other coliforms played as major causative agents[7,10]....   [tags: sulfamethoxazole, uropathogens]

Term Papers
1233 words (3.5 pages)

Essay on Urinary Tract Infection

- Urinary Tract Infection The urinary tract is the body’s is a filtration system that makes sure nutrients are absorbed into the bloodstream and toxins are rejected as waste and come out in liquid form through the bladder and urethra. Any substance unrecognized by this system such as bacteria can cause an infection in this tract system in the body known as urinary tract infection (UTI). The urinary system is made up of the kidneys, the ureters, bladder and urethra. The kidneys take nutrients from liquids that are nurturing to the body....   [tags: Medical Research]

Term Papers
1061 words (3 pages)