Introduction
Alzheimer’s disease is a cognitive disorder characterized by progressive loss of the memory and physical function in humans. It is the most common cause of loss of memory especially in old age. The Alzheimer 's disease onset is slow with symptoms appearing as early as 10 years before the full diagnosis. This condition derived its name from the scientist who first described it, Alois Alzheimer. Alois Alzheimer was a pathologist of German descent who also practiced psychiatric medicine. He described the condition first in the year 1906. The disease commonly affects people of the age over 65 years though it may set in earlier due to genetic risk factors (Stern, 2012).
Causes
The degeneration of brain cells known as neurons is the main cause of the loss of the brain memory function. The neurons are responsible for the transmission of impulses in the brain. The transmission of impulses is through the help of chemicals known as neurotransmitters produced by the neurons. When the neurons degenerate and eventually die in Alzheimer 's disease, the transmission of information in the brain ceases. The hippocampus is the part of the human brain that is responsible for memory. In patients suffering from Alzheimer 's disease, the neurons in this part degenerate leading to the loss of the brain function (Stern, 2012). The cerebral cortex plays a role in language and in the association. The Alzheimer 's disease destroys the neurons in this region too leading to the loss of their function and culminating in the ensuing symptoms characteristic of the disease.
Scientists attribute the degeneration of the neurons in the brain to apoptosis. Apoptosis is programmed cell death. A myriad of natural and artificial factors initiate the premat...
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... and scrabble is an efficient way of being mentally fit to prevent the onset of the Alzheimer 's disease.
For those already suffering from the Alzheimer 's disease, therapeutic and pharmaceutical interventions can help the patients to live a quality life (Citron, 2010). Therapeutic measures include support groups for people with the Alzheimer 's disease, provision of day care facilities for those in the advanced stages. This ensures that the can live a quality life regardless of the cognitive impairment. Support and care from the family is essential to ensure that the dementia patients do not harm themselves. Drugs used to manage the Alzheimer 's disease are mainly of the class of drugs known as cholinesterase inhibitors. These include Donepezil and Memantine HCl that help manage symptoms in the mild and advanced stages of the Alzheimer’s disease (Howard et al, 2012).
The disease called Alzheimer’s is the fourth leading cause of death in the United States (Weiner, 1987). It is estimated that the elderly population will double between now and 2030. During this period, the number of elderly will grow by an average of 2.8% annually (U.S. Census Bureau, 2001). By 2050, the number of people with Alzheimer’s is estimated to range from 11.3 million to 16 million (Alzheimer’s Association, 2005). These startling numbers should prompt an examination into one of the leading causes of death among this group of people. Understanding what Alzheimer’s is and the known causes of the disease are a good starting point. For those who have aging family members, knowing the risk factors and warning signs of Alzheimer’s can be beneficial to both the patient and his family. Finally, once the patient has been diagnosed as having Alzheimer’s, a plan for treatment as well as providing the family and caregivers with a support system can help ease those involved through a very challenging, heartbreaking time.
Alzheimer is a dementia type of disease named after Dr. Alois alzheimer that slowly destroys memory and thinking skills,and eventually , the ability to do simple things, or recognize their family. The first case occurred in the 1906 when a woman died on a unusual mental illness. After she died Dr.Alois examined her brain , amyloid plaques and neurofibrillary. Alzheimer’s is in older people the most common cause of dementia. Dementia is a loss of remembering ,thinking and reasoning skills, that intervenes with your daily life and activities. It is very common in people over sixty years of age. People younger than sixty years can also
Alzheimer’s disease, named after Dr. Alois Alzheimer, is a disease that is on the rise in America and the rest of the world. People should learn as much as they want about this disease, because as you age, your chances of becoming an Alzheimer’s Disease, or AD, patient increases. It is estimated that approximately 3 percent of Americans between the ages of 65 and 74 have the illness, and more than half of all people over age 85 have the ailment.
Alzheimer’s disease is a type of dementia that affects cognitive function in the elderly population. The exact cause of the disease is unknown but may include genetic as well as environmental factors. A progression of specific neurological changes allows the progression of the disease. Short-term memory losses along with dementia are typical symptoms of the disease. A definite diagnosis of the disease currently can only be confirmed by an autopsy. The disease progresses in five stages that will vary with every patient. There is no current acceptable treatment to reverse or stop the progression of the disease.
Nerve cell death and tissue throughout the brain is the most significant affect over time. Naturally by age twenty-five the brain starts to decrease in size. With Alzheimer’s, the amount decrease is extremely significant. The cortex begins to shrivel up which is the part of the brain required for planning, remembering, and thinking. The most noticeable shrinkage occurs in the hippocampus. The hippocampus is responsible for the formation of new memories, it is also located inside the cortex. Upon further inspection under microscope, tissue samples are observed and synapses and nerve cell count is severely decreased. Tangles, are also found which our twisted strands of another protein due to nerve cells dying and bunching together. Plaques and tangles are prime suspects in the death and tissue loss in the Alzheimer’s brain. Beta-amyloid is a chemical and is sticky which causes it to gradually build up into plaques. This chemical derives from a larger protein found in the nerve cells with fatty membranes. These tangles destroy a vital cell transport system made of proteins.
...hed and streamlined to allow for earlier diagnosis. In the case of tertiary prevention, the pharmaceutical companies have a huge financial incentive to create a cure for Alzheimer’s but that is not enough. More government funded research should be dedicated towards finding methods to delay or cure Alzheimer’s disease. The baby boomer generation has already entered their 60’s. As people live longer, as a result of new treatments for common killers such as heart disease and cancer, the chances that they will succumb to Alzheimer’s increases. Failing to find preventative or curative measures will be costly. On a personal level, Alzheimer’s disease slowly attacks cognitive function-the higher thought processes; individuals degenerate into infantile dependents. The cost of caring for increasing numbers of such dependents will be a burden on both family and society.
Memory plays a significant role in the everyday lives of people of all ages. It allows them to recall information and remember skills that were learned in the past. Memory also organizes past information to help people make current and future decisions. However, imagine forgetting the names of close family members or not having the ability to find your keys every time you want to leave the house. These are some of the struggles that people with Alzheimer’s disease face daily. Alzheimer’s disease was first identified by German neurologist Alois Alzheimer in 1906, and was discovered to have an overpowering effect on explicit memory loss (Gruetzner, 1988). There are two types of Alzheimer’s disease – early onset and late onset. Early onset occurs in patients who are diagnosed before the age of 65 whereas late onset occurs in patients who are diagnosed after the age of 65. In the early stages of Alzheimer’s disease, short-term memory is often lost. As Alzheimer’s disease progresses, problems with long-term memory begin to develop, in addition to short-term memory impairments. Although a lot is known about the symptoms of Alzheimer’s disease, the cause has not been conclusively identified. However, as research continues, new theories about the cause of Alzheimer’s disease are being proposed. This has led to a controversy over whether Alzheimer’s disease is caused by genetics or environmental influences (Gruetzner, 1988).
Alzheimer’s is a disease that many people have heard of, but few really know much about. Imagine not being able to remember your loved ones and friends or even how to do simple tasks like dressing yourself and brushing your hair. Now imagine having to dress your mother, who rarely remembers you anymore. This is the reality of life for millions of older people afflicted with Alzheimer’s disease and the families that care for them. Alzheimer’s causes cognitive function to decrease gradually overtime. Alzheimer’s disease is the most common form of dementia - affecting around 5 million Americans (alz.org). It is the most fatal disease affecting older people and needs to be taken seriously.
In the modern age scientists and researchers are constantly discovering new diseases and disorders that affect the human body. With technology improving and new equipment being introduced it enables scientists to gain more knowledge about the disorders than ever before. During the last century a German physician by the name of Alois Alzheimer linked a patient’s memory loss to her brain autopsy which displayed signs of brain shrinkage. His discovery is now known today as Alzheimer’s disease; which is a form of dementia and is a psychological disease that causes the brain to deteriorate. In today’s day and age, there are still many unanswered questions about Alzheimer’s disease (Crider, A., Goethals, G., Kavanough, R., & Solomon, P. 1989). A few known facts are that Alzheimer’s disease is it is most commonly found in elderly humans, with majority of carriers being age 60 or older. It is important to note that Alzheimer’s disease is not an old person’s disease and that it can also be found in adults of younger ages. Furthermore, there are two forms of Alzheimer’s disease. The two forms are called Early-onset which is found in adults ages 30-59 and Late-Onset which is more common and occurs in adults ages 60 and up. Alzheimer’s disease may not be curable, however with the right information it can be easy to conquer (Alzheimer and Dementia Resources).
It is inevitable that eventually each of us will grow old and begin to face more and more health problems as our age rises. Elderly people are challenged by many illnesses and diseases that unfortunately, are incurable. One disease that becomes more common as people age is Alzheimer’s disease. Alzheimer’s a common cause and a form of dementia and can severely damage a patient’s cognitive functions and can ultimately cause death. Living with Alzheimer’s disease can be saddening for both the sufferer and the family. Family and friends will find it very hard to cope when a loved one begins slipping away and losing memory of who they are.
...urrently incurable, and only two drugs--tacrine (Cognex) and donepezil hydrochloride (Aricept)-- have been approved by the FDA for its treatment. Several other drugs are being prescribed more often as their benefits are demonstrated in wider testing. Nonetheless, the mainstay of treatment for a person with Alazheimer’s continues to be good nursing care, providing both physical and emotional support for a person who is gradually able to do less and less for himself, and whose behavior is becoming more and more erratic. Modifications of the home to increase safety and security are often necessary. The caregiver also needs support to prevent anger, despair, and burnout from becoming overwhelming. Becoming familiar with the issues likely to lie ahead, and considering the appropriate financial and legal issues early on, can help both the patient and family cope with the difficult process of the disease. Regular medical care by a practitioner with a non-defeatist attitude toward Alzheimer;s is important so that illnesses such as urinary or respiratory infections can be diagnosed and treated properly, rather than being incorrectly attributed to the inevitable decline seen in Alzheimer’s.
About ten percent of the nerves in the cerebral cortex die as the disease progresses, causing the person to lose previously created synapses (connections between nerve cells). Neurofibrillary tangles, which are abnormally twisted and knotted strands within nerve cells in the cerebral cortex, also contribute to the cognitive impairment. Nerve cells in the brain lose the ability to create vita...
A myth about Alzheimer disease says that nothing can be done about the disease. This is not true. Much can be done to assist the person with Alzheimer’s disease to maintain the highest possible level of functioning as long as possible and in providing the highest quality of life.
Alzheimer’s disease is the fourth leading cause of death in the United States. It affects many people of different age groups, usually older people though. Alzheimer’s gets worse over time, and can lead to long-term care if symptoms are bad enough. People suffering from Alzheimer’s are directly affected in their memories and thought processes, due to the damage in their brain.
Alois Alzheimer, presented a case history of a woman who suffered from a rare brain disorder. The autopsy of her brain identified plaques and tangles. These plaques and tangles work together to break down the brain’s structure. Today, the disease can be characterized by these plaques and tangles. Plaques arise when another protein in the fatty membrane surrounding nerve cells gets sliced up by a particular enzyme. This results in the formation of Beta-Amyloid Proteins, which are sticky and have a tendency to clump together. This clumping is what creates what we know as plaques. These clumps block signaling and communication between cells and also triggers immune reactions that cause the destruction of disabled nerve cells. In Alzheimer’s Disease, neurofibrillary tangles are built from a protein known as tau. The brains nerve cells contain a network of tube-like structures that act as a highway for food molecules among other things. Usually, the tau protein ensures that these tubes are straight, allowing molecules to pass through freely. However in Alzheimer’s Disease, the protein collapses into twisted strands or tangles making the tubes disintegrate, obstructing nutrients from reaching the nerve cell and leading to cell death. The destructive pairing of plaques and tangles starts in a region of the brain called the hippocampus. Alzheimer’s disease is a progressive and degenerative disorder that attacks the brain's neurons resulting in loss of things such as memory, thinking and language skills, and behavioral changes. Dementia is a general term for a decline in mental ability. Alzheimer's is the most common type of dementia. Dementia is not a specific disease. It is a broad term that describes a wide range of symptoms associated with a decline in memory or other thinking skills severe enough to reduce a person's ability to perform everyday activities. Alzheimer's disease accounts for