There has been a new step in science leading towards evolution. Alphagan P has been recognized as the next leading pharmaceutical in treating Glaucoma. It is gentle to the ocular surface, unlike other medications which can harm it. Alphagan P provides IOP lowering which is comparable to beta blocker, but is without the adverse affects that most other medications cause. It is an alpha-2 agonist, which is a class of drugs that bind to and stimulate alpha-2 adrenergic receptors, causing responses comparable to those of adrenaline and noradrenaline.
Alphagan was first introduced in 1996. The latest generation of “adrenergic agonist” is thrity times more selective for alpha 2 receptors than apraclonidine. Because of its selectivity, it does not include the alpha 1 side effects that affect the heart and blood pressure. The most significant side effects are drowsiness, a dry mouth, and fatigue. There is also surface irritation, with about “7 to 15 percent of patients experiencing allergic conjunctivitis. Alphagan has stayed popular since it first came out despite its side effects.
What should you know about Alphagan P before using it? Make sure to not use brimonidine ophthalmic (Alphagan P) if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 2 weeks. Inform your doctor if you have kidney or liver disease, heart disease, circulation problems such as Raynaud's or Buerger's disease, high blood pressure, have a history of fainting or low blood pressure. Make sure to not use the medication if you use contact lenses because the medication contains a preservative that can be absorbed by soft contact lenses. If ...
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...wing through with their education. Studies are now being done to further investigate this occurrence.
Although Alphagan P has a list of adverse reactions reported, it is still the most used medication used to treat patients with Glaucoma. Many clinical studies have been done on the drug since it came out in 1996, and further enhancements have been made since.
Works Cited
Osborne, S., Montgomery, D., Morris, D., & McKay, I. (2005). Alphagan allergy may increase the propensity for multiple eye-drop allergy. Eye, 19(2), 129-137. doi:10.1038/sj.eye.6701441
Bowman, R. C., Cope, J. J., & Nischal, K. K. (2004). Ocular and systemic side effects of brimonidine 0.2% eye drops (Alphagan®) in children. Eye, 18(1), 24-26. doi:10.1038/sj.eye.6700520
ALPHAGAN P: THE NEXT STEP IN THE EVOLUTION OF GLAUCOMA THERAPY. (2003). Review of Ophthalmology, 10(9), 8.
Racemic albuterol is a β2- adrenergic agonist that is a 50:50 mixture of two isomers, (R) albuterol and (S) albuterol. These two isomers are mirror images of each other, and rotate light in opposite directions. (R) Albuterol is an active isomer and in this combination acts an active bronchodilator. The other half of the mixture, (S) albuterol, does not actually possess any bronchodilator activity and was until recently considered an “inactive” distomer or physiologically inert. The “R” stands for rectus or right, while the “S” is for sinister or left. Racemic albuterol was synthesized for maximal airway smooth muscle dilation while minimizing the α- and β1-receptor mediated effects on the cardiovascular system.
The same thing can happen and does happen within our classrooms. Often, teachers are put under pressure to follow strict curriculum and pacing
Saxena, Rohit, Diguijay Singh, and Praveen Vashist. “Glaucoma: An Emerging Peril.” Indian Journal of Community Medicine 38.3 (2013): 135-7: Proquest. Web. 7 Jan 2014.
The following information regards to the pharmaceutical medication albuterol. This medication is one of the most prescribed treatments for asthma symptoms in modern western medicine. Albuterol may be known as: Aerolin, Asmaven, Asthalin, Buventol, Broncovaleas, ProAir, Proventil, Salbutamol, Sultanol, Ventolin, and others.1 Knowing this, the contents that follow apply to each of the names above, and they will all be referred to as albuterol. The background of the medication, its chemistry, pharmacology, toxicology, and therapeutic application are compiled together from multiple reliable resources for the purpose of acquiring a brief informational document on the main aspects of albuterol in society.
(1) Rossi S, editor. doxycycline , Australian medicines handbook. (electronic version) Adelaide: Australian Medicines Handbook Pty Ltd.;
Discuss the possible drug and excipient-related constrains of the formulation (no identity of the drug was given to you at this
Japanese doctors were advised to watch for side-effects and avoid combining Xeplion with other antipsychotics.
... “The Best Step-Up Regimen for Uncontrolled Asthma in Children.” Medscape Today. 25 May 2010. Web. 01 June 2010. .
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Taillandier, J., Ammar, A., Rabourdin, J.P., Ribeyre, J.P., Pichon, J., Niddam, S., Pierart, H. (1986). Treatment of cerebral aging disorders with Gingko biloba extract. A longitudinal multicenter double-blind drug vs. placebo study. Presse Medicale, 15(31) Sep. 25, 1583-7.
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