With the development of CT equipment and technology, coronary CT angiography (CCTA) is widely recognized by clinicians as a non-invasive tool to evaluate coronary arteries [1]. Although the improvement of CT technology is followed by a higher diagnostic accuracy of CCTA [2], the contrast medium (CM) injection protocol is relatively simple during CCTA. In the clinical practice, the CM injection protocol with a constant speed and volume is conventionally used, and the body weight tailored CM injection protocol has been reported in only a few literatures [3-5]. As different concentrations of contrast media, especially a low concentration of contrast media, are widely used in clinic [6、7], there is an issue to be solved during CCTA, i.e., how to use the individualized injection protocols for different concentrations of contrast media so as to reduce the difference of enhancement effect caused by the difference of contrast medium concentration and thus acquire the coronary artery images with a similar enhancement effect. This study aimed to achieve a similar enhancement effect of coronary arteries by the weight-adjusted use of different concentrations of contrast media and thus optimize the use of contrast media and improve the image quality. In the present study, we compared the weight-adjusted iodine-dose protocol for different concentrations of contrast media (the content of iodine in 1kg contrast media was identical) and the fixed iodine-dose protocol.
Coronary arteries have a small diameter and are routing tortuous, and CCTA image quality is critical for diagnostic accuracy, while the reasonable use of CM is one of major factors that influence imaging. An appropriate CM enhancement level is beneficial for the visualization of cor...
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Coronary artery disease is a heart disease characterized by narrow arteries and restricted blood flow in arteries and is the major cause of morbidity and mortality globally.[1] According to WHO estimation, 6.8% in men and 5.3% in women are affected globally.[2-4] Cardiovascular disease account for 29% of all deaths in Canada; of all the cardiovascular death, 54% and 23% was due to ischemic heart disease and heart attack, respectively. The total costs for heart disease and stroke were more than $20.9 billion every year. [5,6] With more than 1 artery impacted, multivessel coronary artery disease is more complex and more likely accompanied by other comorbidities including diabetes or high blood pressure; multivessel coronary artery disease usually is more difficult to deal with, has worse prognosis and cost more compared with single coronary artery disease. [7]
O’Rourke [13] describes the pulse wave shape as: “A sharp upstroke, straight rise to the first systolic peak, and near-exponential pressure decay in the late diastole.” Arteries are compliant structures, which buffer the pressure change resulting from the pumping action of the heart. The arteries function by expanding and absorbing energy during systole (contraction of the cardiac muscle) and release this energy by recoiling during diastole (relaxation of the cardiac muscle). This function produces a smooth pulse wave comprising a sharp rise and gradual decay of the wave as seen in Figure 5. As the arteries age, they become less compliant and do not buffer the pressure change to the full extent. This results in an increase in systolic pressure and a decrease in diastolic pressure.
A Growing Concern." Internet Journal of Radiology 5.2 (2007): 4. Academic Search Premier. Web. 23 Nov. 2013.
Coronary artery disease (CAD) is the most common type of multifactorial chronic heart disease. It is a consequence of plaque buildup in coronary arteries. The arterial blood vessels, which begin out smooth and elastic become narrow and rigid, curtailing blood flow resulting in deprived of oxygen and nutrients to the heart [1].
The study of cardio physiology was broken up into five distinct parts all centering on the cardiovascular system. The first lab was utilization of the electrocardiogram (ECG). This studied the electrical activities of the heart by placing electrodes on different parts of the skin. This results in a graph on calibrated paper of these activities. These graphs are useful in the diagnosis of heart disease and heart abnormalities. Alongside natural heart abnormalities are those induced by chemical substances. The electrocardiogram is useful in showing how these chemicals adjust the electrical impulses that it induces.
Cost effectiveness and noninvasiveness seem to be a theme in developing preventative treatments of coronary artery disease. A study presented by the Journal of Magnetic Resonance Imaging proposes that the use of coronary wall MRI would encompass both of these factors. These MRI images compared coronary artery thickness of symptomatic and asymptomatic patients. It was found that these images could successfully detect artery wall thickness in asymptomatic patients who would have otherwise not been screened for risk factors.
...survivors of myocardial infarction, number of damaged arteries is correlated with vitamin D binding protein. Vitamin D deficiency is correlated with high prevalence of double or triple vessel CAD and lower brachial artery flow-mediated dilations. Animal studies, including two studies conducted on atherosclerotic monkeys support the reverse association between concentrations of VDRA with plaque size and thickness. This association was not observed in monkeys with low VDR and high 25(OH)D3.
Coronary heart disease came in the public eye in the mid-20th century as a disease of pandemic magnitudes and it continues to be a major cause of death in the western world. The fundamental cause of coronary heart disease is Atherosclerosis. The term “atherosclerosis” is the combination of two Greek words which correctly imply the elements of the lesion. The first being “athero” the greek work for gruel which parallels to the necrotic core at the base plaque formation, and “sclerosis” from the Greek word hardening, corresponding to the fibrous cap on the outer layer of the plaque. (Vulnerable Atherosclerotic Plaque : Strategies for Diagnosis and Management, 1, 2)
Coronary heart disease or coronary artery disease affects 16.8 million people in the United States and causes more than 607,000 deaths annually (Lemone, chap.30). It is caused by atherosclerosis which is the accumulation of fatty deposits in the arteries causing impaired blood flow to the myocardium. CAD or coronary artery syndrome is usually without symptoms but may induce heart attack, angina and acute coronary syndrome if not properly treated. There are many risk factors associated with CAD like obesity, high cholesterol diet, hereditary, physical inactivity, just to name a few. Patients with CAD may be unable to identify and manage their risks factors. It is imperative for nurses to educate the patient about CAD and measures to enhance their health.
There are almost 7 million Americans in the United States that suffer from Coronary Artery Disease today. The prognosis for many of these patients depends upon the major therapeutic option of medical management that they choose to receive, the most essential variables that predict the prognosis and likelihood for future events are the extent and severity of the disease at the time of diagnosis. Basically, this translates to mean that the more abnormal the scans and tests are, the higher the prognosis is going to be for future coronary events to occur and therefore the higher the prognosis is going to be for a shorter life span, the lower the progression of the disease the higher the chance is going to be for a longer life span for the patient. A higher risk patient is going to be one with extensive defects from the disease, a patient with little to no defects is going to be low risk, and those with limited defects are going to be at a more intermediate risk. Whether it is because of their familial history of the disease or because of risk factors such as smoking, high blood pressure, high cholesterol, or obesity really does not matter considerably because many of the 500,000 deaths that occur from this disease could be prevented if more of the risk factors were prevented. This disease is the number one killer of both men and women older than 65 years of age because coronary artery disease in contracted as a result from the narrowing of the coronary arteries that feed the heart, and when those arteries become clogged and cannot supply enough blood, oxygen and nutrients in the coronary arteries, people develop chest pains, also more commonly known as angina which is a secondary condition of having Coronary Artery Disease. . These t...
In United States, according to American Heart Association, Cardiovascular disease also called Heart Disease is number one cause of death in United States. There are different types of heart disease and one of them is Coronary Heart disease or Coronary Artery Disease/CAD. Coronary Artery disease or CAD is the most common type of heart disease for both men and women. It is unannounced and can be a silent killer. CAD is mostly can be from damaged or diseased arteries. Some conditions, habits, or traits may increase the risk of CAD and the more problem shows, th...
AIM: - the aim of this experiment is to find out what the effects of exercise are on the heart rate. And to record these results in various formats. VARIABLES: - * Type of exercise * Duration of exercise * Intensity of exercise * Stage of respiration
Images of human anatomy have been around for more than 500 years now. From the sketches created by Leonardo da Vinci, to the modern day Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) scan, images have played a great role in medicine. Evolution in medical imaging brought together people from various disciplines such as Biology, Physics, Chemistry and Mathematics, a collaboration which has further contributed to healthcare as a whole. Modern day imaging improves medical workflows by facilitating a non-invasive insight into human body, accurate and timely diagnostics, and persistence of an analysis.
Hillman, Bruce J. (1997, September 6). Medical imaging in the 21st century. The Lancet, vol. 350, p. 731.