A Medical Model Using Molecular Profiling Essays

A Medical Model Using Molecular Profiling Essays

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For a lot of illnesses such as a cold or an upset stomach, most people would take a general medication like painkillers or a general decongestant for clearing a blocked nose as a “one size fits all”. Personalised medication is defined by the European Commission as “a medical model using molecular profiling for tailoring the right therapeutic strategy for the right person at the right time, and/or to determine the predisposition to disease and/or to deliver timely and targeted prevention.” (Personalised Medicine Coalition, 2014) (Directorate General for Health and Consumers; Directorate General for Research and Innovation, 2013). Personalised medicine was accepted quickly and a dedicated journal, “Journal of Evidence Based Medicine” was launched (Davidoff, et al., 1995) and has even been used in ancient times when herbal remedies were tailored towards age and gender.
Molecular biology techniques allow scientists to find the root causes of diseases and to divide patients into groups that have different genotypes which react differently to different treatments with more or less success or more or less adverse side effects. New treatments can target specific proteins or even protein polymorphisms that cause the disease. Personalised care can also be linked to better patient satisfaction (Cuticaaa, et al., 2014).

Personalised Medicine is now more widely considered now with the discovery of single nucleotide polymorphisms (SNPs) and the development of microarrays (Pucheril & Sharma, 2011). It involves using information from the patient’s phenotype (disease patterns and symptoms) and their genotype (Their physiological and pathological genetic and genomic profile) (Kumar, 2011). Knowing what genes are expressed in a tumour and the ge...


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... believe that personalised medicine is a more efficient way of treating diseases once the economic and ethical issues have passed. Doctors in training should be educated on personalised therapy as soon as possible so new discoveries and methods can be put into the public as quickly as possible. As was seen with the human genome project it took 13 years (1990 to 2003) to complete and cost 2.3 billion dollars (NHGRI, 2010). Nowadays, companies are offering to sequence anyone’s genome for just under a thousand dollars and takes about 8-10 weeks upon receiving a DNA sample (Front Line Genomics, 2016). With how easy and affordable personalised medicine is becoming I think that in the near future it will be the most common method of curing out most diseases and maybe even find ways of preventing them from even happening due to the patient’s knowledge of their risk factors.

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