Hypertension In Obese

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But in our study obese with parental history of hypertension showed a statistically significant increase in diastolic pressure and MAP compared to the other two groups probably due to hyperactive sympathetic nervous system because increase in adiposity significantly associated with increase in sympathetic tone. 12 Increased SNS activity leads to increase in the peripheral vasoconstriction resulting in the increased peripheral vascular resistance with rise in the diastolic blood pressure. Although several studies showed a normal range of blood pressure in the offspring of hypertension, 13 some studies reported a increased diastolic blood pressure in the offspring of hypertension.14

In our study the total power of the HRV spectrum was significantly reduced in both obese and non obese normotensives with parental history of hypertension when compared to the controls. Total power mainly reflects the vagal potency in the modulation of cardiovascular activity. 8 As the total power is reduced substantially in obese and non obese normotensive with parental history of hypertension suggested a suppressed vagal drive in the offspring of hypertensive.
Our study showed a decrease HF power in the offspring with parental history of hypertension. This decrease is apparent when HF power was expressed both in absolute values and in normalized units, as the normalization tends to minimize the effect of the changes in total power on the values of both HF. Actually HF component is a quantitative expression of cardiac vagal control. This study clearly suggests that there was a profound parasympathetic alteration mainly a decreased vagal drive in the offspring with parental history of hypertension. A report by Surekharani et al has also reveale...

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...siological process which is attributable to VLF component is still unknown.
In our study we have observed a increased LF/HF ratio in obese and non obese subjects with parental history of hypertension compared with the subjects without parental history of hypertension. Study done on obese and non obese healthy young Indian adults that LF and LF/HF ratio which measures the sympathovagal balance to heart was increased in obese reflecting an increase in sympathetic drive .7 LF-HF ratio is a most sensitive measure of sympathovagal balance. Increased in LF-HF ratio indicates sympathovagal imbalance, with increased sympathetic and decreased parasympathetic activity. In our study we found higher values of LF-HF ratio in obese with parental history of hypertension which indicates a more sympathetically driven cardiovascular system with depressed parasympathetic activity.

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