For reasons unknown, peanut and tree nut (TN) allergies have increased in prevalence in the Western world (Wainstein & Saad, 2015). Peanut allergies, in particular, are the most common cause of food-induced anaphylactic reactions; even a small amount of the allergen can cause symptoms such as urticaria, angioedema, eczema, nausea, vomiting, and wheezing (Husain & Schwartz, 2013). These reactions primarily consist of the interaction between the proteins found in nuts and the digestive and immune systems (White et al., 2015). As there is extensive research taking place in the inhibition and treatment of peanut and TN allergies, the only current long-term solution, as a means of prevention, is complete avoidance of nut products in general (Wainstein & Saad, 2015). To comprehend the effects of a nut allergy, foundational knowledge regarding the anatomy of the digestive and immune system will help explain the pathophysiology of nut allergies and whether or not it is reversible. Many studies and experiments have been performed concerning nut allergies; therefore, this knowledge can determine that peanut and TN allergies are irreversible as there is currently no long-term solution that prohibit the clinical signs and symptoms of an allergic reaction (AR).
An acute hypersensitivity, or AR, consists of an overreaction of the immune system mounted towards a non-infectious material, or allergen. In peanut allergies, this process involves the Immunoglobulin-E (IgE) antibody and the mast cells found in the gastrointestinal (GI) and respiratory tracts (McKinley, et al., 2016). The GI tract, made up of the oral cavity, pharynx, esophagus, stomach, small and large intestine, and ending in the anu...
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...gy of nut allergies, we can better describe the process of peanut and TN allergies as an overreaction of the immune system and treatments used to suppress the clinical presentations. Genetic, environmental, and atomic qualities of the allergen can be potential factors in why individuals develop a peanut or TN allergy. Allergy reversal is something to be aspired for as it can have significant effects on one’s quality of life (Zukiewicz-Sobczak et al., 2013; Vojdani, 2015).
Upon further exploration of potential solutions, it is possible to speculate that although there are many immunotherapeutic, genetic, and behavioural considerations, none of which prove to be permanently effective in reversing a peanut or TN allergy. For this reason, we arrived at the conclusion that peanut and TN allergies are irreversible, and the only solution is building up a slight tolerance.
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