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Recommended: Wilson's disease
A patient presented with symptoms that suggested she might be schizophrenic. With many conditions mimicking schizophrenia, the doctor reviewed the notes from the family and noticed the patient had missed an eye doctor appointment. The physician, very aware an exam could confirm or refute a diagnosis, requested an eye examination be performed. Kayser-Fleischer rings were present in the cornea of her eyes. These rings are deposits of copper and sulfur granules and are greenish-gold in color. They are not always present; however, when they are, they are a classic identifier of Wilson disease. (Holtz, 2006, pp.108-109) Therefore, the eye exam confirmed a diagnosis of Wilson disease for this patient.
While working in England during the early 1900’s, Alexander Kinnear Wilson, an American neurologist, described the disease. (Schilsky & Brewer, 2009) As with many things, because he was the one who originally described it, it is named after him. Wilson disease is also referred to as hepatolenticular degeneration. (Mayo Clinic, 2009).
It is a genetic, chronic disease that stores up excess copper in the liver. Accumulation of excess copper begins at birth. (Children’s Hospital of Pittsburg, 2010)
Copper is an essential trace metal vital to human health, requiring a small, regular intake to maintain homeostatis. According to Copperinfo (2011), “At least 20 enzymes contain copper and at least 10 of these require copper to function.” The brain, the skin, the heart and the immune system all need copper. Ingested copper is absorbed in the stomach and small intestine. From there, it enters the bloodstream, making its way to the liver. (Copperinfo, 2011)
A healthy liver serves as a filter. Part of its functionality is metabolizing carbohydr...
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...cinnati Children’s Hospital, 2009).
A normal liver adequately filters and removes toxins from the body through the urine or bile. A lack of copper homeostatis in a diseased, damaged liver obstructs this process. This excess accumulation of copper in the liver is Wilson disease. Inherited mutated genes, one from each parent, cause the disease. If only one mutated gene is passed on, then the individual is just a carrier and will never be diagnosed with Wilson disease.
It is prevalent worldwide, including several different ethnic groups. It most often affects children and teens from ages 10 to 20 years old. Occasionally there are exceptions and we see diagnoses of Wilson’s in children as young as three and adults over the age of 50. Treatment is available that, if continued for a lifetime, will maintain copper homeostatis and the patient will live a good life.
Wilson had some important roles in World War I that took a tole on his health. Just the fact of being a president is enough pressure. What stands out most after much research is the fact of how much he wanted peace. One would not underestimate by saying he spent his life by trying to have world peace. He was a remarkable president and benefited our nation tremendously by his works.
"Parkinson Disease." Genetics Home Reference. Lister Hill National Center for Biomedical Communications, n.d. Web. May 2012. .
on the account of ancient Indian texts relating to the Ayurveda medical system which identified the disease as Kampavata. Many others have identified Parkinson’s throughout time as either the “shaking palsy” or its Latin form “paralysis agitans” (Abramovitz, 10). People such as Middle Age physician Galen in 175 AD and widely known Leonardo Da Vinci all picked up on the presence of Parkinson’s Disease before it’s official description was written in 1817 in
James Parkinson. It’s not certain how long the disease has existed but its probably been around
Addison’s disease is a disorder of the endocrine system. It is a hormonal disorder that can strike anyone, any gender at any age. Addison’s disease has also been called Adrenal Insufficiency (hypocortisolism) because the root of the disease is in the adrenal gland not producing enough of the hormone cortisol, or sometimes not enough of the hormone aldosterone to satisfy the body’s needs.
Parkinson disease (PD), also referred to as Parkinson’s disease and paralysis agitans, is a progressive neurodegenerative disease that is the third most common neurologic disorder of older adults. It is a debilitating disease affecting motor ability and is characterized by four cardinal symptoms: tremor rigidity, bradykinesia or kinesis (slow movement/no movement), and postural instability. Most people have primary, or idiopathic, disease. A few patients have secondary parkinsonian symptoms from conditions such as brain tumors and certain anti-psychotic drugs.
Although most people don't realize it, one of the most weakening diseases of the world can often be found crawling around in the shrubs and tall grasses of a person’s backyard .It does not mean that only dirty yards have this disease but it is found in every Americans backyard. The disease is called Lyme disease. Now I will be elaborating on the disease.
5. Witkop, CJ Jr, Quevedo WC Jr, Fitzpatrick TB, and King RA: Albinism, in Scriver CR, Begudet AL, Sly WS and Valla D: The Metabolic Basis of Inherited Disease, ed 6. New York, McGraw Hill, 1989, p 2905-2947.
Though Addison’s disease affects both male and females, it also affects children. Its most predominant in females than males but more likely to occur between the ages of 30-50 in both. According to Webscape, children who are predisposed have a 30% risk of progression to Addison’s disease. The mortality rate is around 6 to every 1 million in the United State and much higher in other countries; however this number is very deceivin...
What is crones disease? what is a chrones? what is a crones? What is chrome disease? what are the crones?
James Parkinson first discovered Parkinson's Disease in 1817. Parkinson's Disease is a common neurologic disorder for the elderly. It is a disorder of the brain characterized by shaking and difficulty with walking, movement, and coordination. This disease is associated with damage to a part of the brain that controls muscle movement. Parkinson's Disease is a chronic illness that is still being extensively studied.
Hemochromatosis is a disorder that can be inherited from your parents but can also be obtained due to excessive consumption of alcohol or iron or blood transfusions. Hemochromatosis is a disorder that causes your body to absorb more iron than it needs. It then stores the iron in crucial parts of your body like your heart, liver, pancreas, brain, and joints. If the iron continues to built it would lead to iron overload. Iron overload can be fatal because of excessive iron in your heart and liver. Continuous iron overload could lead to serious heart conditions like heart attack and heart failure, it could also lead to liver problems, diabetes mellitus, and possibly cancer and death. Symptoms like diabetes mellitus can be avoided if Hemochromatosis
In the case study of an Italian family where of 288 relatives over 6 generations, 29 are affected by the disorder. The average age of onset of the disease is 49, but this may vary with the individual as with one female who was 61 years of age.
Ions are critical to human health. As defined by Dictionary.com, an ion is an electrically charged atom or group of atoms formed by the loss or gain of one or more electrons. The human body is the most intricate of ‘designs,’ despite the fact it is composed of basic natural resources called elements. The ions discussed in this paper include oxygen, carbon, potassium, and sulfur. A healthy body is composed of these ions, along with others (zinc, fluoride, iron, etc.). The absence of these elements could lead to an unhealthy body, and make it an easier target for diseases. The chemical formulas, charges, and properties will also be discussed in this document. Also, addressed is the essential role of the ion presented, the way in which the ion serves the body, the diseases that may result from deficiency, and the global distribution of these deficiencies. Ions are an essential part of human health. The ions that are present make the body’s daily functions possible, allowing it to be protected from cruel bacteria or diseases.
Iyengar, V., & Wolttiez, J. (1998). Trace elements in human clinical specimens: Evaluation of literature data to identify reference values. Clinical Chemistry , 34, 474-481.