Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (SLE) is a long-lasting, autoimmune disease which can affect nearly any part of one’s body. In normal circumstances the body is secured by the immune system. As soon as the immune system identifies harmful foreign substances the body’s usual defense would be for the immune system to abolish the antigens. In lupus suffering patients, the immune system doesn’t have the ability to differentiate regular antibodies from intruders. Lupus is when the body overreacts to a foreign stimulus and creates too many antibodies toward its own body tissue. Hence, Lupus is referred to as an autoimmune disorder. SLE causes inflammation to the joints, organs and tissue. The inflammation is identified as soreness, warmth, swelling and redness.
There are many sgns and symptoms of SLE. Symptoms of lupus tend to vary from each person and range from mild to severe, usually affecting persons between ages 15 and 50. The most commonly reported indicators are joint discomfort, skin rash, stiffness as well as fever. Patients with lupus may experience symptoms that suddenly worsen or appears unexpectedly. Most patients with SLE haves flashes, which signs rapidly appear and worsen and then relax for a long period of time. Nonetheless, the most frequent complaints include lethargy, aching or inflamed joints, fever, skin outbreaks and kidney issues. The butterfly rash, a red rash, is a noticeable sign of lupus and may appear on the face that spreads across the cheeks and nose. Protection against UV rays is very important because many suffer from photosensitivity. Other symptoms consist of brittle hair, mouth ulcers, chest pain, anemia, dry eyes, bruising, menstrual irregularities and paleness. Patients a...
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...udies, the etiology of lupus is possibly linked to heredities, environmental (natural) factors, drug-induced lupus, and is related with ladies of child-bearing age and menstruation.
References
Gordon, Caroline, and WolfgangL. Gross. Systemic Lupus Erythematosus.
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Urowitz, Murray B. Systemic Lupus Erythematosus. Philadelphia: Saunders,
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Crosbie, D. (2009). Dehydroepinadrosterone for Systemic Lupus Erythematosus. Cochran Database of Systemic.
Acton, Ashton. Systemic Lupus Erythematosus: New Insights for Healthcare Professionals. 2013. Atlanta. Scholarly Editions, 2013. Print.
Seward, Tomas I. Progress in Systemic Lupus Erythematousus Research. New York: Nova Biomedical, 2007. Print.
Schur, Peter H. The Clinical Management of Systemic Lupus Erythematosus. Philadelphia: Lippincott- Raven,1996. Print.
that cause dark red blotches on the skin, usually on the face). Laboratory tests are another consideration of diagnosis. Tests consist of anti-nuclear anti-body (ANA) counts and anti-topoisomerase (an enzyme that reduces super-coiling in DNA by breaking and rejoining one or both strands of DNA). High ANA’s and low anti-topoisomerases are found in patients with Raynaud syndrome. (Desai, 2003) “Patients with circulating autoantibodies, antinuclear antibodies, and anti-Scl 70 antibodies are at (an) increased risk of developing a connective tissue disease. Systemic sclerosis is the connective tissue disease most frequently associated with Raynaud’s phenomenon.” (Bowling, 2003) This syndrome is described as primary Raynaud phenomenon (PRP) if is not associated with another disorder and as secondary Raynaud phenomenon (SRP) if it occurs in association with another disorder.
...ll understood simply because of the numerous genetic and environmental factors possible in causing any part of PDB, either by over stimulating osteoclast precursors, genetic mutations, producing transduction pathways that would otherwise not be present or even signals misfiring or over active parathyroid gland. Much more isolated research is necessary before this disease can be fully understood.
Flaccid dysarthria results from damage to the lower motor neurons (LMN) or the peripheral nervous system (Hageman, 1997). The characteristics of flaccid dysarthria generally reflect damage to cranial nerves with motor speech functions (e.g., cranial nerves IX, X, XI and XII) (Seikel, King & Drumright, 2010). Lower motor neurons connect the central nervous system to the muscle fibers; from the brainstem to the cranial nerves with motor function, or from the anterior horns of grey matter to the spinal nerves (Murdoch, 1998). If there are lesions to spinal nerves and the cranial nerves with motor speech functions, it is indicative of a lower motor neuron lesion and flaccid dysarthria. Damage to lower motor neurons that supply the speech muscles is also known as bulbar palsy (Pena-Brooks & Hedge, 2007). Potential etiologies of flaccid dysarthria include spinal cord injury, cerebrovascular accidents, tumors or traumatic brain injury (Pena-Brooks & Hedge, 2007). Possible congenital etiologies of flaccid dysarthria include Moebius syndrome and cerebral palsy. Flaccid dysarthria can also arise from infections such as polio, herpes zoster, and secondary infections to AIDS (Pena-Brooks & Hedge, 2007). Additionally, demyelinating diseases such as Guilian-Barre syndrome and myotonic muscular dystrophy can also lead to flaccid dysarthria (Pena-Brookes & Hedge, 2007). The lower motor neuron lesion results in loss of voluntary muscle control, and an inability to maintain muscle tone. Fasciculations, or twitching movements, may occur if the cell body is involved in the lesion (Seikel et. al., 2010). The primary speech characteristics of flaccid dysarthria include imprecise consonant production, hypernasal resonance, breathiness, and harsh voice (...
Shingles is a rash on the skin that is caused by the varicella-zoster virus, which is the same virus that causes chicken pox. The rash is extremely painful and is accompanied with many additional symptoms. The first symptoms are located on one side of the body and include tingling, pain, or burning sensations around these areas. The second symptom of Shingles is a red rash that develops in patches on the skin. Finally the rash then develops into small blisters that end up bursting, drying out, and then flaking off. Other common symptoms include abdominal pain, general ill feeling, headaches, and joint pain (Sampathkumar, P., et al, 2009).
Lupus is a chronic inflammatory disease that occurs when your body’s immune system attacks healthy tissue and organs. This inflammation can damage many different bodily systems. Lupus commonly affects the joints, skin, kidneys, lungs, brain and heart. Many people with lupus have found relief for some of their chronic pain through practicing a few different styles of yoga.
When someone has lupus they have a different outlook on life. For patients with this disease, even the easiest task can be painful to the body or joints. Lupus is not contagious. “Lupus is a disease of the immune system. The immune system protects the body from inflection”(http://lupus.webmd.com). With lupus, the immune system attacks the tissue in many parts of the body. Lupus affects women more than men(www.womenshealth.gov). There are many different types of lupus, and each symptom affect different parts of the body. With treatment you can obtain and fulfill a healthy lifestyle.
Commonly know as founder, laminitis is caused by a metabolic disease. Inside the hoof there is a structure called laminae that is made up of epithelium tissue. The laminae is what supports the distal phalanx or coffin bone and hoof wall. Laminitis is when the laminae start’s to degenerate. When the laminae starts to degenerate there is no support for the coffin bone inside of the hoof wall. Depending on the severity the coffin bone can actually go through the sole of the hoof. Laminitis can affect all four feet but it is the most common in the forelimbs.
Usually your body produces antibodies to fight off invaders such as Viruses or diseases but since Lupus is an autoimmune disease; the immune system can’t tell the difference between foreign invaders and healthy tissues. There 3 types of Lupus Systemic Lupus (most common) which can affect any part of the body, Discoid Lupus which only affects the skin, and Drug induced Lup...
...ronically, mercury can trigger lupus in some situations, so mercury may have catalyzed the lupus (Lerner).
It has been documented that the exact cause of this disease is unknown but could be caused by environmental factors. 1 The Mayo clinic further stated that an autoimmune disease is when auto antibodies attack your body’s own tissue. Their assumption is that an unknown occurrence in the body triggers the onset of Polymyositis...
Did it ever occur to you that one day you’ll wake up sick and never get better? Well, 60,000 Americans find themselves fighting an autoimmune disease referred as Lupus. There are different types of Lupus, the most common form of Lupus is called Systemic Lupus Erythematosus. (S.L.E) This kind of Lupus causes internal inflammation to organs, joints, and tissue. Also, another type of Lupus is Discoid Lupus Erythematosus. (D.L.E) develops as a rash on the skin after being exposed to sunlight or fluorescent light. (“What You Should Know about Lupus,”n.d)
What is Crohn’s Disease – Aimee Rouski Inspired Published on June 5, 2016 in Health What is Crohn’s Disease? See the recent post by Aimee Rouski on Facebook. I became curious about Crohn’s Disease.
We have all heard stories of a friend or family member trying to conceive but failing at it for unknown reasons. They spend years, thousands of dollars and many tears only to still not conceive. Then, the woman is finally given the diagnosis of endometriosis. Based on statistical evidence and studies endometriosis is the leading cause of infertility in woman of reproductive age. Not only is it a devastating diagnosis but also an extremely hard disease to diagnosis. At times getting misdiagnosed and ignored by medical professionals. Leading to more years of pain for the woman suffering from a very debilitating disease.
The symptoms of psoriasis differ from type to type, although inflamed, scaly lesions are present in all five types. The most common form of the disease, plaque psoriasis, is identified by small bumps that begin to grow and become scaly. These lesions flake easily, but removing these patches can cause the tender skin below to bleed. In the Guttate type, small, individual, red drops form. This type does not have as much scaling as plaque psoriasis. The drops usually clear up on their own, but may also reappear as a different form of psoriasis, usually plaque. Inverse psoriasis usually occurs in places where the skin folds, such as the genitals, breasts, armpits or the backs of knees. This type will appear red, yet it will be smooth and dry. Also, no scaling will occur. Pustular psoriasis is a type that's significantly more rare. It is also more painful. In this type, blisters filled with non-infectious pus appear within a few hours and then dry up and peel within another two days. Severe medical risks exist for those who have this particular form of psoriasis, due to its side effects; exhaustion, anemia, weight loss, fever, chills, rapid pulse rate, severe itching and muscle weakness. Even less common than pustular psoriasis is erythrodermic psoriasis. This type is...
One of the most common mysteries in the world is the development of autoimmune diseases. An autoimmune disease is when the immune system, which usually keeps your body healthy thinks that your healthy cells are antigens and attacks them. This is irony right? It is against properties of evolution for an immune system to attack itself causing sickness and possibly death if untreated. There are about 80 different types of autoimmune diseases, which usually have periods of little to no symptoms and worsening symptoms. What particularly creates confusion in the world is the autoimmune disease, inflammatory bowel disease, which affects almost about five million people worldwide.