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a dialouge about human cloning
human cloning today
human cloning today
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The first Human Cloned Embryo
Article written by: Jose B. Cibelli, Robert P. Lanza and Michael D West, with Carol Ezzell
(summary)
Parthenogenesis is a process of generating human embryos from only eggs put therapeutic cloning within reach
On October 13, 2001 the scientist of Advance Cell Technology come to see that their laboratory cells were dividing, the first human embryos were cloning.
The scientists were hoping for the cells to divide into 100 or so cells called blastocysts. They wanted to take these blastocysts and have them grow to replace nerve, muscle and other tissues. But only one of them came to the Six-cell stage and by then it stopped dividing. They had done a similar procedure they had eggs grow without sperm to fertilize, to develop parthenogenetically into blastocysts they think that using these to procedures together they could achieve human cloning.
In 2001 scientist attempted to create a cloned human embryo, they had consulted all the necessary sources before getting the “ok” to begin “creating”. Then they had to find a female subject to donate eggs. To start the process of cloning they need to use a very fine needle and get the genetic information from a mature egg. Then they inject it into the nucleus of a donor cell. The female donors were asked to take psychological and physical tests to screen for diseases and what not.
Cloning was first attempted last July, because it depended on the menstrual cycles of the subjects, the subjects also had to take hormones so that they would ovulate 10 or so eggs at once.
They seemed to have had a touch of success when the nucleus of a fibroblast had appeared to divide but it never completed. It took 71 eggs from seven volunteers before they could create their first cloned embryo. Out of the eight eggs with cumulus cells, two of them divided to form early embryos of four cells and another went to at least six cells before it stopped growing.
Human embryonic stem cells are derived from fertilized embryos which are less than a week old. In November of...
A somatic cell nuclear transfer, which is also commonly referred to as a SCNT, is the process in which the result is considered a clone. This process includes multiple steps, one in which being the transfer of a somatic cell’s nucleus into an enucleated egg cell. This results in an embryo, which has a variety of uses. If the embryo is used for it’s stem cells, then the outcome will be a genetically identical organ instead of a full clone. This type of cloning could have many practical applications in the future. If the embryo is instead inserted into a uterus, the embryo will grow into a full clone. This type of cloning is called reproductive cloning and both types of cloning have sparked controversy among many due to a variety of ethical
The process of cloning may look like twenty-first century science but the history of cloning goes back all the way to 1885. Hans Adolf Edward Dreisch was the first person to ever demonstrate the process of artificial embryo twinning. By simply shaking a two celled sea urchin embryo he made a landmark discovery. When shaken the two celled embryos split apart creating two identical celled embryos. After the cells separated they grew into two sea urchins. This discovery proved two things, that embryos have their own genetic instructions, and have the ability to grow into a complete organism.
Therapeutic cloning involves the cloning of embryos for the production of stem cells. Therapeutic cloning extract the nucleus from the somatic cell then inserted into the egg, which had its nucleus previously removed. The egg is now stimulated to divide and shortly forms a cluster of cells known as a blastocyst. This blastocyst has both an outer and inner layer of cells and it is the inner layer. The cells in the inner cell mass are isolated and then utilised to create embryonic stem cell lines, which are infused into the patient where they are ideally integrated into the tissues, imparting structure and function as
“The process of therapeutic cloning is simple: a scientist extracts the nucleus (which contains genetic material) and then extracts the nucleus of a somatic cell (any body cell except sperm and egg cells). Next, the somatic cell nucleus is inserted into the egg [of a donor female]. The egg now contains the patients DNA. The egg is simulated to divide shortly after and forms a cluster of cells known as a blastocyst. Cells in the center of the blastocyst are isolated and utilized to create stem cell lives which are infused into the patient where they are ideally integrated into the tissues imparting structure and function as needed.”
Cloning is not new; experiments with frogs and toads go back to the 1970’ with the experiments concerning animal and plant embryos have been preformed for
Since 1885, there have been a number of researchers, scientists, geneticists, reproductive technologists and embryologists, such as August Weismann, Hans Spemann, Walter Sutton, Paul Berg, Steen Willadsen, et al., who have contributed much to the research and development of our current concepts of cloning. Particularly two of the more recent renowned contributors to cloning research and experimentation are Ian Wilmut, a Ph. D. in animal genetic engineering, and Richard Seed, who founded Fertility and Genetics in the 1980s.
The topic I chose was cloning, but I will be focusing on Human Cloning. Dolly the sheep was the first mammal to be created using cloning technology in 1997. With the birth of Dolly the sheep it had raise of a possibility of one day being able to clone human. It took 277 times to create dolly the sheep although it suffers from arthritis and premature aging. In December 2002, a religious group of Raelin claimed that a human baby was cloned but it had not been scientifically confirmed. In 1962 John Gurdon claimed to have cloned South African frogs from the nucleus differentiated adult intestinal cells. In 1964, F.E Stewart grew a complete carrot plant using the carrot root cells and to prove that cell cloning was possible. Francis Crick and James Watson were the first pioneers to discover double helix structure of DNA in 1953. It increased the scientific research of learning about human genetic codes and discovers the possibility of cloning. According to Vos (2004), “In 1984, Steen Willadsun cloned a sheep from embryo cells, which were the predecessor to Dolly’s method of cloning.” In 2002 Boisselier chemist and CEO of Clonaid, cloned Eve the first baby to be cloned and was 7lbs; she is known to be a healthy and happy baby. Eve was created by an America woman of 31 years old who donated her DNA for a cloning process. The woman didn’t give her name, but her embryo was implanted and then gestated to the baby, with that it would make an identical twin as an exact genetic duplicate of the mother. The reason why she decided to donate her DNA was because her husband was infertile of resorted cloning.
...on of human embryos but they successfully argue that the benefits of therapeutic cloning outweigh the morally based objections regarding the process” (2011). Furthermore they emphasize the fact that human lives are spared and improved by the use of genetic engineering and that the destruction of human embryos can eventually be omitted out of the process in a near future through other forms of technology.
As technological advancement grow, scientists begin to speculate the realistic doing of human cloning, as this happens opposing groups and organizations raise their voice against it and create the question whether scientists should be allowed to clone humans, the promise of cloning at any level can revolutionize the world, and change it for the better, but are we are not ready for human trials. If successful, cloning can have a lot of positive technological advancements that would help humanity. Dolly, the first cloned mammal, inspired many scientists to speculate a new era in cloning technology and raise hopes for future probability in which human cloning was possible. At the center of the controversy, surges the closest thing to a clone that lives a healthy and regular life, identical twins. The promise of cloning at any level can revolutionize the world, and change it for the better, but are we really ready for human trials?
The only cloning leading up to the 1930’s was done by Hans Spemann, Walter Heape, and Hans Adolf Eduard Driesch. In 1885 Hans Adolf Eduard Driesch separated two sea urchin cells to create two separate sea urchins. In 1890 Walter Heape used in vitro fertilization,”a medical procedure whereby an egg is fertilized by sperm in a test tube or elsewhere outside the body”(Oxford), to create a rabbit. In 1902 Hans Spemann split
historical timeline” 2010). This early reproductive cloning technique was like forcing the creation of twins through the separation of a blastula. Mister Dreisch did not intend to be the start of a new scientific study. He was simply a scientist who was studying genetics
...rshal, V.S., and Jones, J.M. 1998. Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147.
Research involving embryos is restricted to the first 14 days of development which is the point where the fetus starts to form. Further study can significantly increase mankind’s knowledge about human development, but there are difficulties continuing the studies due to the short time limit. After years of trying, a close cousin of mine is now pregnant, ecstatic that she finally has a chance to have the child she longed for. Her husband, with a look of despair recently told me about how there are studies that collect human embryos in an attempt to learn more about life only to destroy them after their usage expires. After seeing the anguish that they found in these studies, I became more interested in the topic. With the possibility of the
Lauritzen, Paul. Cloning and the Future of Human Embryo Research. Oxford: Oxford UP, 2001. Google Books. Web. 12 Feb. 2014. source 12 (google books)