Suppositories are the frequently used dosage forms prescribed through rectal route. However, suppositories have the limitation of prolonged onset of action which can be attributed to poor drug release properties of suppository base. Surfactants can increase the drug release to aid absorption by reducing the interfacial tension between rectal fluids and the suppository base. The objective of this study was to examine the effect of different concentrations of sodium lauryl sulphate and tween 80 on
Suppositories are the unit solid dosage form designed to be inserted into the rectum. They are useful in avoiding first pass effect, to get sustained release effect and for giving drug to unconscious, pediatric and geriatric patients. In recent years, the suppositories have been widely used in different clinical units with ease and good therapeutic outcomes. Therefore, the present article attempts to review the ingredients, preparation and evaluation arts, and the recent work done in the field of
Suprapubic Catheter Home Guide A suprapubic catheter is a rubber tube with a tiny balloon on the end. It is used to drain urine from the bladder. This catheter is put in your bladder through a small opening in the lower center part of your abdomen. Suprapubic refers to the area right above your pubic bone. The balloon is on the end of the catheter that is in your bladder. It is filled with germ-free (sterile) water. This keeps the catheter from slipping out of place. When the catheter is in place
Hemorrhoids! The “Rectal Rocket” suppository is designed to treat hemorrhoids in 3 days or less**. It is more effective than a traditional suppository because of its unique design and comfort fit. It remains positioned for many hours to soothe and treat the enlarged and swollen tissue without getting lost in the rectum. The contoured top portion of the suppository is inserted into the rectum and treats internal hemorrhoids, while the larger flared base of the suppository remains on the outer surface
as their cultural requirements. It would not be appropriate to recommend treatments that do not align with the patients’ culture. For example, some cultures do not believe in the use of suppositories. Thus is would be inappropriate to prescribe a patient diagnosed with ulcerative colitis Canasa®, a rectal suppository. Instead it would be more appropriate to initiate an oral regimen of mesalamine in order to improve adherence (Kornbluth & Sachar,
receptor-drug complex which promotes the binding of GABA. [edit] Pharmacokinetics [edit] Absorption Diazepam is usually administered in orally in tablet form. Alternatively, also available formulations are intravenous form, intramuscular form, suppository form or rectal solution. In oral form diazepam is quickly absorbed and has a fast onset. It also has a high oral bioavailability of over 90%. The average time it takes for diazepam to reach peak plasma concentration is one to one and a half
As of right now, abortion is legal in all nine months of the pregnancy for any reason. This controversial issue is a question of how important the value of life is. The turning point came in 1973 when the Supreme Court's decision in Roe vs. Wade saying, that women have the right to murder an innocent child only up to 24 weeks . This false perception is fueled part by groups supporting abortion rights and it is then uncritically unaccepted by the media. The fact is that the current law allows a woman
have them other than the itching and blood. Most hemorrhoids respond well to warm (not hot) baths with Epsom salts. After the bath, many doctors recommend using an ice pack to numb the area and shrink the swelling. Hydrocortisone creams and suppositories are often used, and many people wipe Since the most common cause of hemorrhoids in seniors is constipation, this is a good place to start. Constipation can be avoided by eating a diet high in fiber and drinking plenty of water to maintain proper
(2013) and the Official Journal of the AGA Institute (2015): first-line treatment is therapy with 5-aminosalicylic acid (Mesalamine). Other trade names include: Apriso (Extended Release capsules), Asacol & Lialda (Delayed Release tablets), Canasa (suppository), Pentasa (Controlled Release capsules) and Rowasa (Enema). This drug is used to subside inflammation and treat mild
Erectile Dysfunction (Impotence) A kind of sexual dysfunction that affect men is generally termed as erectile dysfunction or impotence. As a result, the person will not be able to develop or maintain an erection of the penis during sexual intercourse. The term and condition is familiar for most of the people in the current society. It can be considered as one of the main causes for infertility issues. Studies have also found another surprising fact that, worse erectile dysfunction may increase the
patient started to complain about the heat. We let maintenance know and they checked the room thermostat but said the ac set to the lowest and to close the blinds so the room can be cool. Mr. G.I had a fever on 100.1 F and was given a Tyelenol suppository. The patient tolerated the medication and extra blankets were removed. I was supprise how time was moving so fast it was now 9am. Mr. Adrlley, RN and I was only able to give two of the patent there morning medication before a new admission came
USED FOR LABOR INDUCTION? Several methods of labor induction may be used, such as: Prostaglandin medicine. This medicine causes the cervix to dilate and ripen. The medicine will also start contractions. It can be taken by mouth or by inserting a suppository into the vagina. Inserting a thin tube (catheter) with a balloon on the end into the vagina to dilate the cervix. Once inserted, the balloon is expanded with water, which causes the cervix to open. Stripping the membranes. Your health care provider
Ulcerative Colitis Ulcerative colitis, or UC, is a chronic gastrointestinal disease that causes inflammation and ulcers in the lining of the large intestine. It causes ulcers in the colon and rectum. Ulcerative colitis is one of two forms of inflammatory bowel disease. In UC, the inflammation from the ulcers breaks down the lining of the colon and causes bleeding and discomfort in the abdomen. Researchers are unsure of what triggers UC, but have two strong possibilities. One theory is that the
What is a drug addiction? A drug addiction is something that is hard to overcome. Sometimes it happens intentionally or sometimes it happens by accident and by accident I mean someone is prescribed a medication by a doctor and they become addicted to it. Intentionally, on the other hand, is when a doctor prescribes a medication and they intentionally abuse it. Prescription drugs aren’t the only things that are addicting, drugs like marijuana and heroin are addicting as well. In a more specific definition
Women’s health Improper balance good and bad bacteria inside the vagina can cause serious uncomfortable infections such as yeast infections and bacterial vaginosis. Some studies have shown that probiotics such as L. acidophilus when taken as vaginal suppositories can support antibiotics in preventing and treating vaginal infections. Safety of Probiotics Studies have shown that probiotics may trigger an allergic reaction, which may manifest through diarrhea, mild stomach upset, bloating and flatulence in
Trainspotting is a 1996 Scottish black comedy/drama directed by Danny Boyle based on the novel by Irvine Welsh written in 1993. The screenplay was written by John Hodge and the story of the movie is narrated by Renton (Ewan McGregor). In the movie, the young Scottish heroin addicts commit every crime they possibly can to leave the audience in shock and disbelief. The movie follows a group of heroin addicts, so called “friends” that live in economically depressed Edinburgh, the capital of Scotland
HISTORY OF THE COMPANY The very first manufacturing plant that Alkaloid grew from was of the ownership of the family Ognjanovich. At the very beginning, there were only 2 manufacturing plants, worked on by a total of 15 employees (of whom only one had a University Degree) to produce 350 kg of pharmaceutical raw materials. The factory extracted an industrial branch not only locally but in the entire region. The main production was in making opium alkaloids (morphine base extraction). The main
Changes and Impacts of the Birth Control Industry in the 1930s For much of the 19th and early 20th centuries women had a hard time getting their hands on effective birth control. The Comstock Act in the United States restricted anyone from using contraceptives or spreading information about it, but those laws did not stop women from trying to prevent pregnancy. Women’s lack of education and effective advertising played an important role in birth control’s highly successful market. This essay will
means it can easily be made into various salt forms. It is the purest form as a white pearly substance. It is metabolized in the liver and when mixed with alcohol cocaethylene. Cocaine can be taken orally, sniffing, injection, inhalation and suppository. Between 2000 and 2006 deaths from cocaine abuse approximately doubled, rising to over 6,000 deaths per year. Cocaine was historically used as a topical anesthetic in eye and nasal surgery but, has been replaced in western medical practices. The
The thyroid gland is located in the anterior, middle portion of the neck. Many of the bodies’ hormones come from the thyroid. According to Porth 2011, “the thyroid hormone increases the metabolism and protein synthesis in nearly all of the tissues of the body.” (p. 784). When these hormones are not regulated, a thyroid disorder develops such as hypothyroidism and hyperthyroidism. Hypothyroidism develops when the thyroid gland does not produce enough of certain hormones. (“Hypothyroidism”, n.d.)