Thyroid hormones are Tyrosine based hormones that require triidothyronine (T3) and Thyroxine (T4). These hormones are produced by the thyroid gland. The Thyroid gland is primarily known for the regulation of metabolism, as well as proper production of T3 and T4. Iodine is the main component that is needed. Dysfunction of Iodine can lead to decreased production of T3 and T4, resulting in enlarged thyroid tissue and even lead to thyroid diseases. In order for the thyroid hormone to function adequate amount of Thyroxine (T4) should be found within the blood. Thyronines on the other hand act on nearly all cells inside the body. Their function is to increase basal metabolic rate, affect protein synthesis, help regulate long bone growth, and increases the body’s ability of being sensitive to catechoalmines. Thyroid hormones are highly essential for proper development and differentiation of all cells within the body. Thyroid hormones also play a role in the regulation of protein, fat, and metabolism of carbohydrates and vitamins. Various physiological and pathological effects serve to influence thyroid hormone synthesis.
Introduction
The thyroid gland is one of the largest endocrine glands located in the neck. The thyroid glands major role is determining how the body uses energy, makes proteins and how sensitive it is to other hormones found in the body. With a healthy thyroid gland one can produce sufficient thyroid hormones needed for the body. The following elaborates on the thyroid hormone , from anatomy and function , production, and known diseases.
Thyroid Gland: Anatomy and Function
This gland is located between the vertebrae column, in front of the trachea and just below the larynx. It consists of two lobes known as lobus ...
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Conclusion
As seen, thyroid hormones play a vital role in the body. With it being produced by the thyroid gland, thyroid hormones take part in metabolism, growth and development and its necessity of Iodine is crucial in order to continue proper production.. The unique structure and function this shows helps in determining how important the thyroid hormone is for the proper development of the thyroid gland in the body. Without Iodine, the abnormalities that occur interfere with thyroid hormone production and increase the likelihood of developing diseases due to the lack of Iodine .The mechanism of Iodine serves as the major component to induce proper production of thyroid hormones via the thyroid gland. With the evidence and understanding of the function , the need for thyroid hormones can be seen as an important asset for the human body.
I should remember the lecture note that parafollicular cells of the thyroid gland produce calcitonin.
The location of the pituitary gland is in the sella turcica of the sphenoid bone and attaches to the hypothalamus(Marieb & Hoehn 441). The Hypothalamus is included in the function of the pituitary gland as it sends chemical stimulus to it(Marieb & Hoehn 442).Part of the pituitary is called the “ master endocrine gland” due to the fact that is produces many hormones that affect the whole body(Shannon 175).This part of the pituitary gland is called the anterior pituitary(Marieb & Hoehn 601). There are six hormones that the anterior pituitary secretes normally. These Hormones are growth hormones,thyroid stimulating hormones,adrenocorticotropic hormones,luteinizing hormones,follicle stimulating hormones and prolactin hormones( Shannon 175).The Hormone prolactin is one that in normal function stimulates the act of lactation for new mothers to feed their baby(Shannon 175).
The thyroid gland is located in the anterior, middle portion of the neck. Many of the bodies’ hormones come from the thyroid. According to Porth 2011, “the thyroid hormone increases the metabolism and protein synthesis in nearly all of the tissues of the body.” (p. 784). When these hormones are not regulated, a thyroid disorder develops such as hypothyroidism and hyperthyroidism.
Thyroid and metabolism hormones play a large role in the daily lives of all living species. Thyroid hormones regulate the metabolism and the metabolism is responsible for maintaining a specific range for the biochemical reactions that occur in the body (Martini 2014). The most important hormone for metabolic maintenance is thyroxine (T4). This hormone also plays a large role in body heat regulation. It is produced by the pituitary gland and secreted by the thyroid gland. The thyroid releasing hormone (TRH) must trigger the thyroid stimulating hormones (TSH) to release thyroid hormones to the thyroid gland. These hormones are under control of the hypothalamus, or main neural control center. Propylthiouracil (PTU) is a medication used to treat
Hypothyroidism is an endocrine disorder that effects the lives of many people. In hypothyroidism, the thyroid gland does not produce enough thyroid hormone, causing an array of symptoms such as fatigue, weight gain, depression, swelling of limbs, lack of focus and many more. The current standard of treatment of hypothyroidism is hormone replacement therapy with a synthetic form of thyroxine (T4) called Levothyroxine or T4 Monotherapy. The whole idea behind T4 Monotherapy is that the Levothyroxine (which is a synthetic version of the natural thyroid hormone thyroxine) will mimic what occurs naturally in the body, and be deiodinated in the peripheral tissues to become the more biologically active thyroid hormone triiodothyronine (T3) and thus, alleviating the patients symptoms. Unfortunately, this however, is not always the case. For some patients, even though they are in the therapeutic range using T4 monotherapy, their bodies aren’t properly converting the synthetic T4 to active T3. Because of this, coupled with the invention of the internet, patients are turning to search engines in hopes to find an answer that will alleviate their symptoms, which has led to a resurgence in the use of desiccated thyroid products. Desiccated thyroid is derived from porcine thyroid glands, and contain both T4 and T3 thyroid hormones. Some alternative medical practioners are claiming there is more benefit in this natural product vs synthetic, but perhaps we need to take a closer look into the alternative treatment options of hypothyroidism- such as desiccated products, and why natural might not always be better.
Graves’ disease is an autoimmune disease that was discovered by Robert Graves in 1835. Graves’ disease is an autoimmune disease in which the body's immune system attacks the thyroid gland and causes hyperthyroidism. Graves’ disease occurs when the antibodies like thyroid-stimulating immunoglobulin and thyrotropin receptor antibodies (TRAbs) attack the thyroid gland as if it were a foreign object or a virus of some sort. This disease is the most common type of hyperthyroidism. Attacking the thyroid gland in such a manner makes it excessively overproduce the hormone thyroxine which controls the body’s metabolic rate. Heightened activity of the thyroid can increase the body’s metabolism by 60% to 100%. (Weeks 34-35).
The balance of the thyroid hormone is complicated and involves the participation of different parts of the body (Kaplustin, 2010).
The thyroid gland plays a major role in the endocrine, thyroxine, triiodothyronine and metabolism system. The gland can be found in the front of the neck and above where the collar bones meet. The thyroid gland controls the body by releasing T4 and T3 hormones. Controlling metabolism plays an important role when regulating mood, weight,
The thyroid gland is found in the front of the neck and produces two main hormones. The hormones are called thuroxine (T4) and Triiodothyronine (T3). Together these hormones regulate the body’s metabolism by increasing energy use in cells, regulate growth and development, help to maintain body temperature and aid in oxygen consumption. These two hormones are regulated by hormones produced by the hypothalamus and pituitary gland. The hypothalamus senses changes in body’s metabolic rate and releases a hormone known as thyropin-releasing hormone (TRH). This hormone then flows through connecting vessels to the pituitary gland which signals it to release another hormone. This hormone is known as thyroid-stimulating hormone (TSH). TSH then makes its way to the bloodstream until it reaches the thyroid where it is then signaled to activate T3 and T4 production [1]. This mechanism is controlled by a negative feedback loop meaning that when there is a sufficient amount of thyroid hormones in the blood stream, this will signal back to stop production of thyroid stimulating hormones. Complications occur when the thyroid hormones keep increasing even though there is already a sufficient amount of T3 and T4 in the blood stream. This process of over expression of thryroid hormones is known as hyperthyroidism. Hyperthyroidism is a general term that includes any disease that has a consequence of an overabundance of thyroid hormones. Hyperthyroidism is a general term but there are many variant diseases that are in the hyperthyroidism category. These diseases include diffuse toxic goiter, Basedow’s disease, thyrotoxicosis, Parry’s and Graves’ disease.
The pharynx is a large cavity behind the mouth and between the nasal cavity and larynx. The pharynx serves, as an air and food passage but cannot be used for both purposes at the same time, otherwise choking would result. The air is also warmed and moistened further as it passes through the pharynx. The larynx is a short passage connecting the pharynx to the trachea and contains vocal chords. The larynx has a rigid wall and is composed mainly of muscle and cartilage, which help prevent collapse and obstruction of the airway.
two pleural lobes on the sides. The three main parts of it's body are called the
Person, A. & Mintz, M., (2006), Anatomy and Physiology of the Respiratory Tract, Disorders of the Respiratory Tract, pp. 11-17, New Jersey: Human Press Inc.
The thyroid gland is part of the endocrine system, and it is controlled by the pituitary which is known as the “master gland” of the endocrine system. The pituitary controls the thyroid by producing Thyroid Stimulating Hormone (TSH) which stimulates the production of thyroid hormones. . The thyroid gland secretes two main hormones: Thyroxine (T4) and Tri-Iodothyronine (T3). These hormones increase metabolic rate, heat production, oxygen consumption, appetite, growth hormone secretion, alertness and quicker reflexes. The thyroid gland is located in the anterior portion of the neck, beneath the Adam’s apple. It is divided in two lobes on either side of the windpipe: right lobe and left lobe. These lobes create what looks like a butterfly shape. The gland is essential to the contribution of maintaining the homeostasis of the body. It plays a role in monitoring the body’s expenditure of energy and running the body’s metabolism.
Swan, S.H., F. Liu, J.W. Overstreet, C. Brazil, and N.E. Skakkebaek. "Growth Hormones Fed to
Each tear gland is about the size and shape of an almond. These glands are located behind the upper eyelid at the outer corner of the eye. After passing over the eye, the liquid from the gland is drained into the nose through the tear duct at the inner corner of the eye.Heavy laughter or crying causes muscles in the upper eyelid to squeeze the lachrymal gland. This produces tears that flow too fast to be drained away. The eyelashes catch many flying particles that otherwise would enter the eye.