My Account
Preview
Preview

Smallpox : Pathogenesis and Pathology Essay

:: 6 Works Cited
Length: 1605 words (4.6 double-spaced pages)
Rating: Blue      
Open Document
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Smallpox: Pathogenesis and Pathology

Smallpox was eradicated in 1980 by the Center for Disease and control. It is now contained in five labs in the United States and Russia, however there are other labs in the world with smallpox. Smallpox is created from the virus Variola which inoculates itself through the skin and into the dermis or more commonly from prolonged, direct face to face contact. Smallpox incubates for as long as two weeks at which time it is multiplying in the lymph nodes and bone marrow. The virus is also able to enter the blood stream and travel through without being harmed by macrophages. The variola virus also causes monkeypox and cowpox however none of these are as bad or as fatal as smallpox.

Smallpox is transferred through the air from prolonged face-to-face exposure. It is also transferred by skin inoculated into the dermis often in an existing wound. Once a human is infected with smallpox, the virus incubates for a period of ten to fourteen days, at which time the human was not infectious. In the incubation period the variola virus multiplies. Once the incubation period ends smallpox infects the respiratory tract which at this time cannot be detected nor provide any symptoms. Next, the virus replicates in the lymph nodes, bone marrow, and spleen. The smallpox virus creates virions which carry the viral DNA from cell to cell protecting it from the inhospitable conditions of the body. There the infected macrophages and virions infect other macrophages in the dermis thus spreading the virus later causing the pustules on the skin. Necrosis and edema follow causing such legions to leave permanent scars once the pustules scab and fall off (Aguayo).
The first cells to become actively produced f...


... middle of paper ...


...0/vaccinia_virus.html>.

Langohr, I. M., G. W. Stevenson, H. L. Thacker, and R. L. Regnery. "Extensive Lesions of Monkeypox in a Prairie Dog." Veterinary Pathology. 2004. University of California Davis. 24 July 2007 .

Mayo Clinic. "Smallpox." MayoClinic.Com. 12 Aug. 2005. Infectious Disease. 25 July 2007 .

"Smallpox." Armed Forces Institute of Pathology,. 1 Jan. 1970. 27 July 2007 .

"Smallpox Vaccine And Monkeypox." Center for Disease Control. 1 Jan. 1970. 25 July 2007 .

Webmd. "Cowpox Infection, Human." EMedicine.Com. 29 July 2007. WebMD. 23 July 2007 .


Click the button above to view the complete essay, speech, term paper, or research paper








This essay is 100% guaranteed.


Title Length Color Rating  
History and Causes of Smallpox Essay - Introduction Smallpox is a viral disease that causes pus-filled boils on the dermis. It looks similar to chickenpox, but has certain characteristic differences. Unlike chickenpox, smallpox is lethal in 30% of the cases and leaves the victim with disfiguring scars and/or blindness. Smallpox has now been eradicated through aggressive vaccination. The last case was reported in Somalia in the late 1970’s. After 2 years of worldwide surveillance, the World Health Organization (WHO) confirmed that the disease had been eradicated....   [tags: chickenpox, variola virus, smallpox vaccine]
:: 4 Works Cited
865 words
(2.5 pages)
Better Essays [preview]
Forensic Pathology as a Career Essay - Forensic Pathology as a Career The career that I researched was forensic pathology. The job of a pathologist is to determine a person’s cause of death by examining tissues and fluids from the body. A forensic pathologist does this as well, but they are trained to examine people who died unexpectedly or violently and to recognize other things that a regular pathologist might not, such as recognizing something as intentional rather than accidental. They have to determine who the person is, the time of death, the manner of death, and if it was accidental, the instruments which caused the death....   [tags: Forensic Pathology Careers Medical Essays]
:: 3 Works Cited
672 words
(1.9 pages)
Better Essays [preview]
Smallpox Viruses Essay - For approximately three-thousand years, smallpox has ravaged and plagued the four corners of the globe. In fact, in the 17 th and 18 th centuries, it was claimed to be the most infectious disease in the West, with an astounding 90% mortality rate in America. It wasn't until 1796, with English surgeon Edward Jenner's smallpox vaccination, that the world saw relief from this devastating virus. However, even with this inoculation in use, the world continued to witness death from both the virus and the vaccine....   [tags: Smallpox Viruses]
:: 7 Works Cited
2185 words
(6.2 pages)
Powerful Essays [preview]
Variola rex smallpox Essay - Variola rex (Smallpox) Smallpox is a virus that was first founded in ancient times. The virus?s proper name is Variola rex, and it has various different forms as well as various symptoms. Among these forms are typical smallpox, hemorrhagic smallpox, and malignant smallpox, all of which usually always cause death in their victims. Some of the typical symptoms of smallpox include red vesicles and pustules all over, bleeding from all orifices of the body, swelling in the face, throat, and eyes, difficulty eating and swallowing, delirium, malaise, deterioration of the bone marrow, lymph nodes and mucus membranes of the body, and a multitude of other secondary symptoms....   [tags: Biology Medical Biomedical Smallpox] 1307 words
(3.7 pages)
Better Essays [preview]
Overview of Smallpox Essay - One of the world’s most dreaded plagues for centuries, smallpox is now eradicated. Vaccination programs were pushed worldwide by the World Health Organization (WHO) and the disease was eliminated from the world. This push resulted in the last naturally occurring case in the world being almost 40 years ago. Once eradicated the once routine or mandatory vaccinations were stopped for the general public and it was deemed no longer necessary to prevent the disease. Although currently eradicated worldwide, two medical laboratory stockpiles still remain in Russia and the United States....   [tags: vaccination programs, Edward Jenner]
:: 3 Works Cited
1060 words
(3 pages)
Better Essays [preview]
Essay about The Molecular Mechanisms of Prion Pathogenesis - The aim of this report is to present the subject of prion proteins, their association and interaction in biological terms, paying particular attention to their molecular mechanisms. Prions are infectious agents responsible for Transmittable Spongiform Encephalopathy (TSE) diseases1, which are debilitating and progressive neurological diseases resulting in both behavioural dysfunction and severe brain tissue damage. These prion proteins are found in different isoforms, and the development from the healthy protein into the misfolded protein is the cause for these diseases is still very much debated....   [tags: Transmittable Spongiform Encephalopathy]
:: 40 Works Cited
2861 words
(8.2 pages)
Research Papers [preview]
Essay about History of Smallpox - The History of Smallpox Abstract The history of smallpox goes back for thousands of years. It is thought to have appeared as much as 10,000 years ago and since then, it has claimed the lives of millions of people, many of whom have been famous figures in history. After a vaccine was discovered in 1796, countries throughout the world began the fight to eradicate the disease. This fight was won in 1980 as a result of the international effort headed by the World Health Organization. Today, smallpox is no longer a threat in nature but the virus is still stored in labs, from which a biological weapon could be made....   [tags: Biology Medical Biomedical]
:: 6 Works Cited
2436 words
(7 pages)
Strong Essays [preview]
Essay on Bioterrorism with Smallpox - Bioterrorism: Smallpox Smallpox is a highly infectious and fatal disease caused by the Variola virus. It causes extremely painful pustules to sprout across the entire body. Spread from human to human, it has since been eradicated from the world through the efforts of the World Health Organization. However, there is a distinct possibility that it may be reintroduced through bioterrorism. Biological weapons may cause another pandemic to erupt across the world and kill millions of individuals. Through constant vigilance and careful planning, mankind can prevent this scenario....   [tags: Variola virus Terrorism Terrorist]
:: 7 Works Cited
2341 words
(6.7 pages)
Research Papers [preview]
Essay about Smallpox - The Scourge of the World Nestled deep in the bowels of the Centers for Disease Control in Atlanta, Georgia, locked away in a blue and silver freezer lays what remains of humankind’s deadliest enemy. Neatly tucked away in a virology institute in Siberia, guarded twenty-four hours a day, lays it’s counterpart. No, not a man made weapon of mass destruction; just a natural born killer of man. This insatiable killer is known in the scientific community as the Variola Virus. To the layperson, it is called, smallpox....   [tags: essays research papers] 1423 words
(4.1 pages)
Strong Essays [preview]
Smallpox Treatment Essay - Smallpox Treatment Smallpox has threatened our world for the past twelve thousand years. Treatments were desperately searched for until a cure called variolation was discovered. Variolation is the use of the virus placed into a being to which they will receive the illness to a lesser degree and overcome the illness forming an immunization to it. This process was started in China and went worldwide after Lady Montagu took the process from Turkey and informed the British about it....   [tags: Vaccination Vaccine Variolation]
:: 5 Works Cited
2114 words
(6 pages)
Strong Essays [preview]