Significant Role of the Hippocampus

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Significant Role of Hippocampus

Hippocampus is a small, curved region, which exists in both hemispheres of the brain and plays a vital role in emotions, learning and acquisition of new information. It also contributes majorly to long term memory, which is permanent information stored in the brain. Although long term memory is the last information that can be forgotten, its impairment has become very common nowadays. The dysfunction is exemplified by many neurological disorders such as amnesia. There are two types of amnesia, anterograde and retrograde. Anterograde amnesia is inability in forming new information, while retrograde refers to the loss of the past memory. As suggested by Cipolotti and Bird (2006), hippocampus’s lesions are responsible for both types of amnesia. According to multiple trace theory, the author suggests that hippocampal region plays a major role in effective retrieving of episodic memory (Cipolotti and Bird, 2006). For example, patients with hippocampal damage show extensively ungraded retrograde amnesia (Cipolotti and Bird, 2006). They have a difficult time in retrieving information from their non-personal episodic events and autobiographical memory. However, this theory conflicts with standard model of consolidation. The difference between these theories suggests that researchers need to do more work to solve this controversy. Besides retrieving information, hippocampus is also important in obtaining new semantic information, as well as familiarity and recollection (Cipolotti and Bird, 2006). For instance, hippocampal amnesic patient V.C shows in ability to acquire new semantic knowledge such as vocabularies and factual concepts (Cipolotti and Bird, 2006). He is also unable to recognize and recall even...

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...arches, exposing rats to context box repeatedly helps to minimize interference caused by contextual information (Kim, 2014). Kim also suggests that after treatment of bicuculline, increasing of spatial memory and contextual learning interfere with encoding information, therefore, alter the recollection process.

References

Cipolotti, L., & Bird, C. M. (2006). Amnesia and the hippocampus. Current opinion in

neurology, 19(6), 593-598.

Eichenbaum, H., Otto, T., & Cohen, N. J. (1992). The hippocampus—what does it do? Behavioral

and neural biology, 57(1), 2-36.

Min, K. J., Hyun, K. D., Lee, Y., Jin, P. S., & Hoon, R. J. (2014). Distinct roles of the hippocampus

and perirhinal cortex in GABAA receptor blockade-induced enhancement of object

recognition memory. Brain research.

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