The Psychological Effects Of LSD

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The Psychological Effects of LSD Introduction LSD has always been a center of controversy in American society, often times because peoplehave been miseducated about its effects or exposed to media bias. Its physiological effects onthe brain and body have become more and more apparent in the last few decades when research in neuroscience peaked. The psychological effects of LSD have been often difficult to describe and document very well -- they were first discovered on April 16, 1943 by research chemist Albert Hofmann when a small amount of the drug soaked through his fingers during a routine synthesis. He experienced an imaginative dream-like state for a duration of about 2-3 hours. Since then, a great deal of work has been done attempting to document the health effects of LSD. Acute Effects LSD is very potent: the effective dose is measured in micrograms (ug) -- however, the lethal dose is literally thousands of times that, making the drug essentially non-toxic. There have been only a few cases of possible overdose where people ingested extremely large amounts of the drug (Allen et al., 1978; Griggs et al., 1977). LSD can be administered a number of ways, the most common: orally through paper, sugar cubes, on a piece of gelatin, or by pill; intravenously; or intramuscularly. A standard dose withnoticeable hallucinogenic effects is about 100-200 ug. The intensity of the trip is proportional to the size of the dose -- it is interesting to note, though, that the duration of the trip seems to stay the same at higher doses (Freedman, 1984). The initial effects begin 20-40 minutes with a sense of euphoria and dizziness. Hallucinations then begin to occur, with the trip peaking for 4-5 hours after about an hour since the drug is taken. LSD is best described as a drug that strikes down barriers. The person who uses LSD is likely to feel detached from his/her ego, and can cross between states of consciousness. The user's perceptions are altered, causing visual and auditory hallucinations. One may notice that the walls of room are "breathing" or that motionless curtains appear to be moving. Senses appear to mix: a user might see music, taste colors, or hear visual stimuli. The LSD experience is often difficult to describe by users -- words lose meaning and ... ... middle of paper ... ...s. Journal of Nervous and Mental Disease. 130:30-40. · Freedman, D.X. (1984): LSD: The bridge from human to animal. In: Jacobs, B.L. (Ed.) Hallucinogens: Neurochemical, Behavioral, and Clinical Perspectives. New York: Raven Press. · Griggs, E.A. & Ward, M. (1977): LSD toxcity: A suspected cause of death. J. Ky. Med. Assoc. 75:172-173. · Hoffer, A. (1970): Treatment of psychosis with LSD. In Gamage, J.R. & Zerkin, E.L. Hallucinogenic Drug Research. Beloit, Wisconsin: Stash Press. · Loughman, W.D., Sargent, T.W. & Israelstam, D.M. (1967, 27 October): Leukocytes of humans exposed to lysergic acid diethylamide: lack of chromosomal damage. Science. 158:508-510. · Ludwig, A. (1970): LSD treatment in alcoholism. In Gamage, J.R. & Zerkin, E.L. Hallucinogenic Drug Research. Beloit, Wisconsin: Stash Press. · Pahnke, W.N., Kurland, A.A., Unger, S., Savage, C. & Grof, S. (1970): The experimental use of psychedelic (LSD) psychotherapy. In Gamage, J.R. & Zerkin, E.L. Hallucinogenic Drug Research. Beloit, Wisconsin: Stash Press. · Vardy, N.M. & Kay, S.R. (1983): LSD psychosis or LSD-induced schizophrenia? A multi-method inquiry. Arch. Gen. Psychiatry. 40:877-83.

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