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a brief summary of skeletal muscle
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Anatomy of Muscle Cells
There are three types of muscle tissue in the human body. These muscle tissues are skeletal muscles, smooth muscles and cardiac muscles. Each of these muscle tissues has it very own anatomical makeup, which vary from muscle to muscle. The muscle cells in a muscle are referred to as muscle fibers, these fibers are skeletal muscle fibers, smooth muscle fibers and cardiac muscle fibers.
The anatomy of a skeletal muscle fiber is formed during embryonic development. Skeletal muscle fibers arise from a hundred or more small mesodermal cells called myoblasts. The mature skeletal muscle fiber has a hundred or more nuclei. Once fusion occurs the skeletal muscle fiber will lose the ability to undergo cell division. This means that the number of muscle fibers is set before birth and most of these fibers will last a lifetime.
The muscle growth that occurs after birth is a result of the enlargement of these existing muscle fibers. The mature muscle fibers have a few myoblasts, which remain as satellite cells. These myoblasts retain the capacity to join with one another or with damaged muscle fibers in order to regenerate these muscle fibers.
John Centore2
Dr. Jain
Anatomy & Physiology
The many nuclei of skeletal muscle fiber are located underneath the sarcolemma, which is the fiber’s plasma membrane. Thousands of invaginations of the sarcolemma, which are called T Tubules, Tunnel from the surface to the center of the muscle fiber. These T Tubules are open to the outside of the fiber and are filled with extra-cellular fluid. Muscle action potentials propagate along the sarcolemma and through the T tubules and quickly spread through the muscle fiber. This process ensures that all parts of the muscle fiber become excited by an action potential virtually simultaneously.
The sarcoplasm is located inside the sarcolemma. Sarcoplasm is the cytoplasm of a muscle fiber, it contains a good amount of glycogen, which is used for ATP synthesis. The sarcoplasm also contains myoglobin, a red colored, oxygen binding-protein, that is found only in muscle fibers. The myoglobin binds oxygen molecules, which are needed for ATP production within the mitochondria. The Mitochondria lie in rows throughout the muscle fiber, strategically close to the proteins that use ATP during contraction.
The sarcoplasm is filled with little threadlike structures. These str...
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...sponse to nerve impulses, hormones and other local factors. These muscle fibers can also stretch considerably and still maintain their contractile function.
John Centore5
Anatomy & Physiology
Dr. Jain
The last of the three groups of muscle fiber is cardiac muscle fiber. The cardiac muscle fibers have the same arrangement of actin and myosin and the same bands, zones, and Z-disks as skeletal muscle fibers. However, the ends of cardiac muscle fibers connect to adjacent fibers by irregular transverse thickenings of the sarcolemma called intercalated disks. These disks contain desmosomes, which hold the fibers together, and gap junctions, which allow muscle action potential to spread from one cardiac muscle to another.
In cardiac muscle fibers, calcium ions enter the sarcoplasm both from the sarcoplasmic reticulum and from extracellular fluid. The mitochondria in cardiac muscle fiber are larger and more numerous than in skeletal muscle fiber. Cardiac muscle fibers can also use lactic acid produced by skeletal muscle fibers to make ATP, a benefit during exercise.
I had already submitted my Email is Johnnynip@aol.com,please excuse me for forgetting my email address....thank you
In the beginning phases of muscle contraction, a “cocked” motor neuron in the spinal cord is activated to form a neuromuscular junction with each muscle fiber when it begins branching out to each cell. An action potential is passed down the nerve, releasing calcium, which simultaneously stimulates the release of acetylcholine onto the sarcolemma. As long as calcium and ATP are present, the contraction will continue. Acetylcholine then initiates the resting potential’s change under the motor end plate, stimulates the action potential, and passes along both directions on the surface of the muscle fiber. Sodium ions rush into the cell through the open channels to depolarize the sarcolemma. The depolarization spreads. The potassium channels open while the sodium channels close off, which repolarizes the entire cell. The action potential is dispersed throughout the cell through the transverse tubule, causing the sarcoplasmic reticulum to release
The Tenth Amendment was added to the Constitution of 1787 by James Madison due to the problem with its predecessor, the Articles of Confederation. In Article 2 in the Articles of Confederation it states, “Each state retains its sovereignty, freedom and independence, and every Power, Jurisdiction, and right, which is not by this confederation expressly delegated to the United States, in Congress assembled.” With states having too much sovereignty this caused an issue. Madison was a Federalist and believed that the federal government should have some control over states, therefore, he proposed the 10th Amendment. By the constitution getting rid of state sovereignty it meant Anti-Federalists fearing the possibility of a federal government with unlimited power. However, the states were able to compromise and ratify the Constitution under the agreement that powers not stated on it are reserved to the states or to the people. The 10th Amendment overall gives clarification that federal power is limited and that states or the have control on the issues not stated on the constitution. However, not everyone agreed to the 10th amendment. It was seen as
Six million Jews died during World War II by the Nazi army under Hitler who wanted to exterminate all Jews. In Night, Elie Wiesel, the author, recalls his horrifying journey through Auschwitz in the concentration camp. This memoir is based off of Elie’s first-hand experience in the camp as a fifteen year old boy from Sighet survives and lives to tell his story. The theme of this memoir is man's inhumanity to man. The cruel events that occurred to Elie and others during the Holocaust turned families and others against each other as they struggled to survive Hitler's and the Nazi Army’s inhumane treatment.
In Elie Wiesel’s Night, he recounts his horrifying experiences as a Jewish boy under Nazi control. His words are strong and his message clear. Wiesel uses themes such as hunger and death to vividly display his days during World War II. Wiesel’s main purpose is to describe to the reader the horrifying scenes and feelings he suffered through as a repressed Jew. His tone and diction are powerful for this subject and envelope the reader. Young readers today find the actions of Nazis almost unimaginable. This book more than sufficiently portrays the era in the words of a victim himself.
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Since the publication of, Night by Eliezer Wiesel, the holocaust has been deemed one of the darkest times in humanity, from the eradication of Jewish people to killing of innocents. Wiesel was one of the Jewish people to be in the holocaust and from his experience he gave us a memoir that manages to capture the dark side of human nature in the holocaust. He demonstrates the dark side of human nature through the cruelty the guards treat the Jews and how the Jews became cold hearted to each other. Wiesel uses foreshadowing and imagery, and metaphors to describe these events.
Many themes exist in Night, Elie Wiesel’s nightmarish story of his Holocaust experience. From normal life in a small town to physical abuse in concentration camps, Night chronicles the journey of Wiesel’s teenage years. Neither Wiesel nor any of the Jews in Sighet could have imagined the horrors that would befall them as their lived changed under the Nazi regime. The Jews all lived peaceful, civilized lives before German occupation. Eliezer Wiesel was concerned with mysticism and his father was “more involved with the welfare of others than with that of his own kin” (4). This would change in the coming weeks, as Jews are segregated, sent to camps, and both physically and emotionally abused. These changes and abuse would dehumanize men and cause them to revert to basic instincts. Wiesel and his peers devolve from civilized human beings to savage animals during the course of Night.
Wiesel, a survivor of the Holocaust, shows how the Germans mass exterminated the Jews out of Germany. He also tells his story of the atrocities he saw and endured for survival through Night main character Eliezer. On the other hand, Browning shares the stories of the German perpetuators, specifically German Order Police. Even though Wiesel would probably never feel empathy for the German perpetuators, many of the Order Police were once ordinary men who had no intentions of killing, with some who eventually enjoyed killing. This shows that those of the German Order Police and the Jews were psychologically ruined
At a bookhouse, a woman chooses to burn and die with her books and afterwards Montag begins to believe that there is something truly amazing in books, something so amazing that a woman would kill herself for (Allen 1). At this point in the story Guy begins to read and steal books to rebel against society (Watt 2). Montag meets a professor named Faber and they conspire together to steal books. Montag soon turns against the authorities and flees their deadly hunting party in a hasty, unpremeditated act of homicide, and escapes the country (Watt 2). The novel ends as Montag joins a group in the county where each person becomes and narrates a book but for some strange reason refuses to interpret it (Slusser 63). Symbolism is involved in many aspects of the story. In Fahrenheit 451Ray Bradbury employs various significant symbols through his distinct writing style.
In the 1940s under the rule of Adolf Hitler, German soldiers caused great destruction throughout Europe. Elie Wiesel, a young boy at the time, was caught in the traumatic crossfire of the devastation occurring in that time period. The memoir, Night, tells the horrific stories that Elie Wiesel experienced. Elie was forced into concentration camps with his dad where he soon had to grow up fast to face the reality of his new life filled with violence, inhumanity and starvation, many of which he had never endured before. In Elie Wiesel’s novel Night he validates his theme of violence and inhumane treatment toward Jews through the use of excessive force such as the brutal beating to show Eliezer that he should not have been roaming the camp and
According to a piece of literature “Constitutional Myth #7: The 10th Amendment Protects States ' Rights” by Epps, he states that the concept of states ' rights outdated by 1860. He explains that the original thirteen colonies in the 1700s, separated from England, were making own decisions and ignoring the rules imposed on them from abroad. During the American Revolution, the founding fathers compromised with states in order to ensure the Constitution was ratified and the create the establishment of the United States. For further points, the original Constitution actually would ban slavery, but Virginia would not allow it as well would Massachusetts would not ratify the document without a Bill of Rights, showing 10th amendment in play before it was even
The articles of confederation were adopted by the continental congress on December 15, 1777. It created a weak central government leaving most of the power to the states. Even though this was what the anti-federalist wanted they knew they needed a change in government. The articles of confederation states in section two that “Each state retains its sovereignty, freedom, and independence, and every power, jurisdiction, and right, which is not by this Confederation expressly delegated to the United States, in Congress assembled.” This is where the tenth amendment derived from with certain modifications. Both the tenth amendment and the articles of confederation state that the powers not listed are reserved for the states. The reason why the tenth amendment was included was because of the fight that the anti-federalist put up. They demanded state and individual rights so James Madison drafted up the bill of
The experiment that tested the contractile level of muscle in various solutions used a muscle fiber from rabbit’s muscle. One fiber was detached, put under microscope, and submerged first under ATP and salt solution (KCl and MgCl2), then ATP only solution, and lastly salt only solution [2]. The fiber’s level of contraction was measured in micrometers. Muscle contractile strength and number motor units employed at various force lev...
First major symbolism is blood. Blood appears throughout the novel as a symbol of a human being’s repressed soul. Montag’s wife, Mildred attempted suicide by ingesting pills and passed out on the ground. In the quote “ Gaze into the psyche of the person whom he pumped all the blood from the body and replaced it
When a muscle contracts and relaxes without receiving signals from nerves it is known as myogenic. In the human body, the cardiac muscle is myogenic as this configuration of contractions controls the heartbeat. Within the wall of the right atrium is the sino-atrial node (SAN), which is where the process of the heartbeat begins. It directs consistent waves of electrical activity to the atrial walls, instigating the right and the left atria to contract at the same time. During this stage, the non conducting collagen tissue within the heart prevents the waves of electrical activity from being passed directly from the atria to the ventricles because if this were to happen, it would cause a backflow. Due to this barrier, The waves of electrical energy are directed from the SAN to the atrioventricular node (AVN) which is responsible for transferring the energy to the purkyne fibres in the right and left ventricle walls. Following this, there is a pause before the wave is passed on in order to assure the atria has emptied. After this delay, the walls of the right and left ventricles contract