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history of vaccinations
essay on the history of polio
essay on the history of polio
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The Polio Vaccine
The discovery of the polio vaccine was an important medical and scientific breakthrough because it saved many lives since the 1950s. In the summer of 1916 the great polio epidemic struck the United states. By the 1950s hundreds of thousands of people had been struck by the poliomyelitis. The highest number of cases occurred in 1953 with over 50,000 people infected with the virus.
When hygienic conditions were poor polio attacked infants. The disease was spread by contaminated water and contact with fecal contamination. Many infants died when the conditions were poor. But as conditions improved the virus spread differently. It was spread more through playmates and family members, the contamination came from the nose and throat. By the early 1950s, twenty-five percent of paralytic cases occurred in people 21 years old or older.
Jonas Salk M.D. developed the polio vaccine. Salk's vaccine was composed of a "killed" polio virus. This virus kept the ability to immunize while preventing the infection of the patient. Later a "live" vaccine was developed from the live polio virus. This "live" vaccine could be administered orally as opposed to the "killed" vaccine which required an injection. There was some evidence that the "killed" vaccine didn't completely eliminate the virus in the patient. United States public health authorities decided to distribute the oral "live" vaccine to eliminate the polio virus instead of Salk's "killed" vaccine. Unfortunately, the "live" vaccine infected some people instead of immunizing. Countries that used Salk's "killed" vaccine have nearly eradicated the virus.
Jonas Salk received his medical degree in June 1939 from New York University School of Medicine. Dr. Salk moved to A...
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...me additional information about how he created his vaccine.
The Hall of Science and Exploration: Interview page 2; 1-26-99 *http://www.achievement.org/autodoc/page/sal0bio-2*
The interview gave me knowledge of how Dr. Salk thought and felt about what he was doing. It also told me additional information about how he created his vaccine.
The Hall of Science and Exploration: Interview page 3; 1-26-99 *http://www.achievement.org/autodoc/page/sal0bio-3*
The interview gave me knowledge of how Dr. Salk thought and felt about what he was doing. It also told me additional information about how he created his vaccine.
Hargrove, Jim. The Story of Jonas Salk and the Discovery of the Polio Vaccine. Childrens Press: Chicago, 1990
This book told me how Jonas Salk conducted his research and what some of his results were. This may have been my most helpful source.
At first polio was a troubling prospect when it first reared its ugly head in the United States of America. In a noble effort to be rid of polio, America as a whole was to adopt stringent sanitation measures. Everywhere, especially the home was to be spotless and clean in order to try and prevent the contraction of polio. This coupled with the view that America as a western nation seemed impervious to such a lowly disease tried to assuage American fear of the disease. Despite the measures commonly adopted throughout the myriad of cities and towns, polio still managed to spread around the country and wreak havoc taking thousands of lives. An outbreak that ravaged America claimed nearly 27,000 lives in a terrible reckoning before it finally subsided. This and several other troubling outbreaks
Deborah Lee and Rosalyn Carson-Dewitt MD, a medical and scientific writer (Lee, Carson-Dewitt, 2016, p.2), worked together to write Point: Vaccines Save Lives, found on page two of “Point of view: Vaccines and health hazards” to discuss vaccines. Lee’s article used historical events, expert opinion, and comparison to make the argument that vaccines protect society. With people taking what they read on the internet at face value, it is more important than ever to be sure one knows the facts before making decisions. The authors attempted to clarify the subject to help parents make an informed decision. Did Lee and Carson-Dewitt effectively present evidence in an unbiased way to support the claim that vaccines save lives?
In 1947, Salk accepted an appointment to the University Of Pittsburgh Medical School. While working there, with the National Foundation for Infantile Paralysis, Salk saw an opportunity to develop a vaccine against polio, and devoted himself to this work for the next eight years. In 1955 Salk's years of research paid off. Human trials of the polio vaccine effectively protected the subject from the polio virus. When news of the discovery was made public on April 12, 1955, Salk was hailed as a miracle worker. He further endeared himself to the public by refusing to patent the vaccine. He had no desire to profit personally from the discovery, but merely wished to see the vaccine disseminated as widely as possible.
The first discovery was made in 1952, in the developing field of virology. Virology is the study of viruses and how they behave. To develop the vaccines for the viruses, researchers infected the HeLa cells with many types of infections, such as measles, mumps, and the infamous poliomyelitis virus, also known as Polio. According to the Centers for Disease Control and Prevention (CDC), whose mission is to save lives and protect people’s health security, Polio is a "crippling and potentially deadly infectious disease caused by a virus that spreads from person to person invading the brain and spinal cord and causing paralysis" (Freeman). Jonas Salk, who was a virologist at the National Foundation for Infantile Paralysis (NFIP), used inactivated viruses (virus particles grown in culture and then killed by a form of heat) to create a polio vaccine. Salk drew blood from about two million children, which the NFIP checked for immunization.Through the collection of many HeLa cells and trial and error, the polio vaccine wa...
Smith, Jane S. Patenting the Sun: Polio and the Salk Vaccine. New York: William Morrow and Company, Inc., 1990.
Salk’s research led him to create a vaccine different from any other by using 3 different kind of killed polio virus. In an article it says,”Using formaldehyde, Salk killed the poliovirus, but kept it intact enough to trigger the necessary immune response”(Salk’s institute 1). Salk 's decision to create a vaccine out of inactivated virus was not the strongest protector, but was made strong enough to cure and lower the risk of infection within patients. It was one of the first times someone attempted to take a completely opposite approach than what scientist thought was best. As he said in an interview, “ ‘The principle I was trying to establish was that it was not necessary to run the risk of infection, which would have been the case if one were to try to develop an attenuated or weekend polio virus vaccine’ ”( Salk 2). By taking the risk of creating a vaccine that contradicted what a normal vaccine, was it helped give the United States another weapon to fight back polio without exposing americans to the risk of contracting the disease. His different approach to find a remedy may have been looked down on, but it provided the first protection ever for polio which created hope and has contributed to less fatalities today. Scientists in the medical world began to criticize Salk’s vaccine and gave preference to a polio vaccine that was later created by Sabin out of a live polio virus. Medical professionals saw Salk’s vaccine as useless and thought Sabin’ s vaccine was the best alternative. "the oral polio vaccine also came under attack in the united states for causing eight in ten cases of polio every year”( poliomyelitis 4). Sabin’s vaccine may have been stronger but at least Salk’s never provided a risk of the patients being injected run a risk of being infected again. Salk’s vaccine has provided less risk of a patient to relapse into polio again.
Piddock, Charles. "Winning the War on Polio." Current Health 2 10 2004: 25-7. ProQuest. Web. 17 Mar. 2014.
Verbally expressing the word “POLIO” brings forth anxiety, trepidation, and thoughts of mortality, crippled bodies, and iron lungs. Once the first shock wears off that you-- in fact, have the disease than the fight for your life begins. This highly contagious illness was unknowingly transmitted by close contact and in fecal matter. Unfortunately, many poor and middle class families' contracted this viral disease, which rapidly destroyed motor-neurons to arms, legs, and diaphragm muscles. Ironically, improved twentieth- century sanitation practices like enclosed sewers and indoor plumbing were cited for this delayed childhood disease. Younger breastfeeding toddlers received maternal antibodies that protected them from the virus. However, older children did not have this immune advantage, they suffered more debilitative disabilities. Sadly, children under fifteen years old, experienced the highest rates of contracting infantile pa...
Polio: An American Story describes a struggle to find a vaccine on polio through several researchers’ lives, and over the course of many years. The second thesis is the struggle between Salk and Sabin, two bitter rivals who had their own vaccine that they believed would cure polio. The author David M. Oshinsky, is describing how difficult it was to find the cure to a horrifying disease, which lasted from the Great Depression until the 1960’s. Oshinsky then writes about how foundations formed as fundraisers, to support polio research. Lastly, the author demonstrates how researchers were forced to back track on multiple occasions, to learn more about polio.
Many people, mainly kids suffered from polio, which is a disease that causes the child to become paralyzed. This disease was feared greatly at the time, until Dr. Jonas Salk created a vaccination for the disease in 1952. Within six years, the vaccine brought the disease under control. Everybody was really excited for this new vaccination. There are many pictures from the 50s with Dr. Salk himself giving the vaccination to kids. The March of Dimes foundation took many photos; one of the many is of a young boy with his mother, Salk, and a nurse giving the vaccine. This picture is actually his wif...
Fifty-nine years after the vaccine was introduced to the world, the number of cases of outbreaks has dropped 99% and only three countries still remain in an epidemic state with the virus, Nigeria, Pakistan and Afghanistan. In 1994, the WHO Region of the Americas was certified polio-free and in in 2013 only406 reported cases were existent in the world, compared to the 350 000+ cases in 1988. (Who, 2014).
Edward Jenner is often regarded as the “Father of Immunology” for his development of the smallpox vaccine. His remarkable discovery has laid the foundation for future scientists working with immunizations. Jenner’s impact is seen worldwide to this day with the complete eradication of the deadly smallpox virus. Edward Jenner’s Legacy will always live on as the first to vaccinate using a live virus. Vaccines are improving everyday, which benefits the public’s health, all thanks to Edward Jenner.
Vaccines are an integral part of modern preventive medicine. Without vaccines, not only would most malignant epidemics still be around, and the world would also be in a much more polluted era. The streets would be littered with diseased, there would have to be mass graves for the dead, and the healthy would have to be quarantined inside a sterile environment.
Dawson, Liza. "The Salk Polio Vaccine Trial of 1954: Risks, Randomization and Public Involvement in
When children are born and for the first two years of their lives, they receive multiple shots and drops of vaccines. These vaccines protect them from getting diseases that were deadly and common in children many decades ago. Vaccine is one of the greatest achievement in medicine history. There were thousands of lives lost in the battle with some of the terrifying diseases like smallpox and polio. Now, after years of vaccine invention, vaccination spread in many countries which helped in eradicate several illnesses. In the United States, each family is required to show their children's immunization chart in order to get accepted in many educational institutes. Parents usually face the decision whether to vaccinate their children or not when their children are first born. Knowing how vaccines are made and their mechanism to prevent diseases as well as, the process they go through to be approved for public use, can help parents in making the choice for vaccinating their children.