With a huge number of victims, 80 to 100 million, since 1918, the influenza is considered as one of the most pandemic diseases ever. There are three types of influenza virus: influenza virus A, influenza virus B, and influenza virus c. These are a subtypes of the virus family orthomyx-oviride. The types B and C do not cause pandemic diseases while type A does. The type A classified into three main subtype H1.N1, H1.N2, and H3.N2. The (H.N) refers to the two kinds of proteins on the surface of the virus (hemagglutinin and neuraminidase). The difference in numbers is due to the difference in protein variability. A H1.N1 virus which is widely known as Spanish flu is the only type that can transmit from human to human. The H5.N1, or “bird flu” does not transfer between humans, but it occurs in a few cases when it evolves. Bird flu seems to be the same as the Spanish flu, but in new arrangement which means some changes must happen to the virus in order to pass between humans. Apparently, we misconceive the mechanism that the virus works so it appeared again. To lessen the damage from these viruses we need to understand the structure and the mechanism of how the virus spread.
The H5.N1 virus has transmitted to humans since 1997. We all know that virus consists of 16 genes which are a small unit made up of RNA (ribonucleic acid) that carry all characters from one generation to another. These viruses are adopted inside the genome of the birds like ducks. These animals are considered the natural host of these viruses which means that the immune system of the birds recognize the virus as a normal body. According to Debora Mackenzie in news scientists, before 2003, the virus started to spread in chicken farms in East Asia. They have discove...
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...rom anything that could be a potential threat. The bird flu for sure is a potential threat. There are many ways to protect our body, for example, a vaccine which is a substance applied to people in order to perk up their immune system. Sometimes it could be a dead cells from the virus – the virus outside the body is not a living organism so it needs to be at its weakest point. In additions, there are some precautions, and procedure, we should follow which work side by side with the medical ways. Dr. Jeffery Greene in his book the bird flu pandemic, points out that the best way to fight such viruses we need to determent its characters and carrier. The influenza virus dies in high temperature (167-212 °F). It is also ruined by chemical substance such as alcohol, detergents, bleach. We also should take care in public places because all germs lurking on surfaces that app
This extremely pathogenic zoonotic virus is now understood to travel from bat species, to equine intermediate hosts, to humans.[8, 10] The Hendra virus is listed as a Bio-Safety Level (BSL)-4, and can only be studied at a few adequately equipped laboratories worldwide due to its virulence.[1, 2] Case fatality rates
It has not taken human to human transmission yet, that we know of. So far all cases of the virus result from people coming into close contact with bird blood or droppings. If the transmission of the virus does take human to human form, it could unleash a global pandemic. This is the first time in history that humans have been able to prepare themselves for an epidemic. The bird flu virus travels with migrating birds.
The Influenza virus is a unique respiratory viral disease that can have serious economic and social disruption to society. The virus is airborne transmitted through droplets release by coughing or sneezing from an infected person or by touching infected surfaces. Symptoms range from mild to severe and may even result in death. People with the virus usually experience fever, headache, shivering, muscle pain and cough, which can lead to more severe respiratory illness such as pneumonia. People most susceptible to the flu virus are elderly individuals and young children as well as anyone whose health or immune system has been compromise. The most effective way to counteract the influenza virus is to get the flu vaccine which is available by shots or nasal spray before the flu season as well as practicing safe hygiene. (CDC, 2013)
The influenza or flu pandemic of 1918 to 1919, the deadliest in modern history, infected an estimated 500 million people worldwide–about one-third of the planet’s population at the time–and estimates place the number of victims anywhere from 25 to 100 million. More than 25 percent of the U.S. population became sick, and some 675,000 Americans died during the pandemic. The 1918 flu was first observed in Europe, the U.S. and parts of Asia before swiftly spreading around the world. Surprisingly, many flu victims were young, otherwise healthy adults. At the time, there were no effective drugs or vaccines to treat this killer flu strain or prevent its spread. In the U.S., citizens were ordered to wear masks, and schools, theaters and other public
The virus is primarily spherical shaped and roughly 200nm in size, surrounded by a host-cell derived membrane. Its genome is minus-sense single-stranded RNA 16-18 kb in length. It contains matrix protein inside the envelope, hemagglutinin and neuraminidase, fusion protein, nucleocapsid protein, and L and P proteins to form the RNA polymerase. The host-cell receptors on the outside are hemagglutinin and neuraminidase. The virus is allowed to enter the cell when the hemagglutinin/ neuraminidase glycoproteins fuse with the sialic acid on the surface of the host cell, and the capsid enters the cytoplasm. The infected cells express the fusion protein from the virus, and this links the host cells together to create syncitia.
One of the most virulent strains of influenza in history ravaged the world and decimated the populations around the world. Present during World War I, the 1918 strain of pandemic influenza found many opportunities to spread through the war. At the time, science wasn’t advanced enough to study the virus, much less find a cure; medical personnel were helpless when it came to fighting the disease, and so the flu went on to infect millions and kill at a rate 25 times higher than the standard.
Although the Columbian Exchange allowed for the beneficial exchange of cultures, ideas, foods, and animals around the world during the 1450-1750 time period, it also had a dark side. One detrimental result of the Columbian Exchange would be the spreading of smallpox from Europe to the New World.
...influenza pandemic in one way or another; the use of quarantines were extremely prevalent among them. Also, the pandemic is directly responsible for the creation of many health organizations across the globe. The organizations help track and research illnesses across the globe. The CDC (Centers for Disease Control and Prevention) for example, strive to prevent epidemics and pandemics. They also provide a governing body with directives to follow in case an outbreak does occur, and if one shall occur the efforts of organizations across the globe will be crucial for its containment. It is amazing that with modern medicine and proper organization that influenza still manages to make its appearance across the globe annually.
Influenza is a major public health problem which has outbreaks all over the world. Resulting in considerable sickness and death rates. Furthermore, it is a highly infectious airborne disease and is caused by the influenza virus. Influenza is transmitted easily from one person to another person, which has a great impact on society. When a member of society becomes sick, it is more prone to spread to other people.
The influenza pandemic of 1918-1919 killed more people than the Great War, known today as World War I (WWI), at somewhere between twenty and forty million people. (1) Influenza is a virus that appeared in 1918 and caused a pandemic. It made an enormous impact that is still significant to the world today. It has pushed scientists to make advancements in the medicine and vaccination industry that continue to grow each and every day. Influenza may be a horrible thing, but without it we wouldn’t be where we are today.
A few years before 1918, in the height of the First World War, a calamity occurred that stripped the globe of at least 50 million lives. (Taubenberger, 1918) This calamity was not the death toll of the war; albeit, some individuals may argue the globalization associated with the First World War perpetuated the persistence of this calamity. This calamity was referred to the Spanish Flu of 1918, but calling this devastating pestilence the “Spanish Flu” may be a historical inaccuracy, as research and historians suggest that the likelihood of this disease originating in Spain seams greatly improbable. Despite it’s misnomer, the Spanish Flu, or its virus name H1N1, still swept across the globe passing from human to human by exhaled drops of water that contained a deadly strand of RNA wrapped with a protein casing. Individuals who were unfortunate enough to come in contact with the contents of the protein casing generally developed severe respiratory inflammation, as the Immune system’s own response towards the infected lung cells would destroy much of the lungs, thus causing the lungs to flood with fluids. Due to this flooding, pneumonia was a common cause of death for those infected with Spanish Flu. Due its genetic similarity with Avian Flu, the Spanish Flu is thought to be descended from Avian Flu which is commonly known as “Bird Flu.” (Billings,1997) The Spanish Flu of 1918 has had a larger impact in terms of global significance than any other disease has had because it was the most deadly, easily transmitted across the entire globe, and occurred in an ideal time period for a disease to happen.
The human population has a high susceptibility to the contraction of new diseases and outbreaks of these diseases are of high risk. Diseases in recent times that have broken out into the human population are the H7N9 flu strain and SARS. Despite the risk, outbreaks like H7N9 and SARS have been controlled due to epidemiology and other disease control methods. Outbreaks of disease are not uncommon to the human population as they move to new areas around the world with foreign diseases that the native residents would have developed a resistance to.
The swine influenza or swine flu is a respiratory disease in pigs that is caused by the type A influenza viruses. These viruses are referred to as swine flu viruses but scientifically the main virus is called the swine triple reassortant (tr) H1N1 influenza virus. When the viruses infect humans they are called variant viruses. This infection has been caused in humans mainly by the H1N1v virus in the United States. The H1N1 virus originates in animals due to improper conditions and the food they ingest. The virus stays in latency form, thus harmless to the respective animal. The longer the animals survive the more likely the virus is to develop and strengthen making it immune to vaccines. The virus reproduced through the lytic cycle. The virus injects its own nucleic acids into a host cell and then they form a circle in the center of the cell. Rather than copying its own nucleic acids, the cell will copy the viral acids. The copies of viral acids then organize themselves as viruses inside of the cell. The membrane will eventually split leaving the viruses free to infect other cells.
Recent concerns regarding the risks of Avian flu and other exotic diseases prompted some local poultry farmers to adopt strict biosecurity protocols in order to keep their birds safe. ...
(39) World Bank. Projects - Haiti: AVIAN INFLUENZA CONTROL AND HUMAN INFLUENZA EMERGENCY PREPARDNESS AND CONTROL. 2010; Available at: http://web.worldbank.org/external/projects/main?pagePK=64283627&piPK=73230&theSitePK=40941&menuPK=228424&Projectid=P111667. Accessed 6/27/2010, 2010.