Microstructural Brain Injury in Post-Concussion Syndrome After Minor Head Injury

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The article Microstructural Brain Injury in Post-Concussion Syndrome After Minor Head Injury, by ****, studied post concussive symptoms relationship with innovative MRI imaging. Mean diffusivity, fractional anisotropy, and the presence of microhaemorrhages were used to indicate micro-structural brain injury in subjects with minor head injuries. Although they experienced symptoms participants’ CT (computed tomography) and normal MR images did not display any irregularities. Participants contained 21 MHI patients and 12 controls that were healthy who were matched to the ages (between the ages 18 to 50), genders, and educational levels of the MHI participants. The MHI patients were involved with the study 1 month after being in the emergency room with head trauma. All needed a normal neurological inspection and a Glasgow Coma Scale (GCS) of 13-15, which determines the conscious state of an individual. The patients and controls were scanned with diffusion tensor imagining (DTI) and high-resolution gradient recalled echo (HRGRE) weighted sequences. Their cognitive function was assessed with the Mini Mental Status Examination (MMSE). The Rivermead Postconcussion Symptoms Questionnaire (RPSQ) measured the severity of their post-concussive symptoms. A higher score meant that the symptoms were more severe after the injury. Additionally, the number of days before the patients went back to work or school was noted. The results indicated that microhaemorrhages were seen in only one patient. Fractional anisotropy showed a decrease in the subcortical white matter of the right temporal lobe. When correlated to the severity of post-concussive symptoms FA displayed decrease in the uncinate fasciculus, the fronto-occipital fasciculus, the interna...

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...s the symptom severity did not correlate to completing the task correctly.

Works Cited

Lannsjö, M., Raininko, R., Bustamante, M., Von Seth , C., & Borg , J. (2013). Brain pathology after mild traumatic brain injury: an exploratory study by repeated magnetic resonance examination. J Rehabil Med, 45(8), 721-728. doi: 10.2340/16501977-1169

Pardini, J., Pardini, D., Becker, J., Dunfee, K., Eddy, W., Lovell, M., & Welling, J. (2010). Postconcussive Symptoms are associated with compensatory cortical recruitment during a working memory task. Neurosurgery, 67(4), 1020-1028. doi: 10.1227/NEU.0b013e3181ee33e2
Smits, M., Houston, C., Dippel, W., Wielopolski, A., Vernooij, W., Koudstaal, J., Hunink, G., & Van Der Lugt, A. (2011). Microstructural brain injury in post-concussion syndrome after minor head injury. Neuroradiology, 53(8), 553-563. doi: 10.1007/s00234-010-0774-6

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