The Importance of Oral Hygiene

Importance of careful assessment of oral cavity for suspicious lesions for early detection of multiple myeloma.1

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION:

Article title: “The multiple oral presentations of multiple myeloma”.1

Bibliographic information: Richard C. Cardoso & Peter J. Gerngross & Theresa M. Hofstede & Donna M. Weber & Mark S. Chambers. Support Care Cancer (2014) 22:259–267 DOI 10.1007/s00520-013-1960-y.

PURPOSE/QUESTION:

The purpose of this study was:

1) “To show the varied oral presentations of multiple myeloma, illustrating the importance of carefully surveying the oral cavity for suspicious lesions that could be indicative of palpable disease and/or recurrence”.1

2) “The diagnostic criteria and prognostic features for multiple myeloma were also reviewed”.1

SOURCE OF FUNDING:

Information not available.

TYPE OF STUDY/DESIGN:

It is a descriptive epidemiological study. The type of study design is case series. Total five cases with multiple myeloma manifestations involving the oral cavity were reported. Detail data of patient’s medical history, oral cavity lesions description, myeloma treatment and its progression is reported.

Summary

Key Study Factor:

In this study total five patients (3 female and 2 male) from 31 to 70 years old with multiple lesions in oral cavity were reported. Detail report of patient’s medical history, oral cavity lesions location, and description were noted. Diagnosis and treatment of myeloma is well defined with disease outcome.1

Main Outcome Measure:

The outcome of the study was diagnosis or relapse of myeloma.1

Main Results:

Five patients with oral cavity lesions with myeloma were reported.1

Conclusions:

Oral cavity lesions can be ...

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... required. More number of cases with oral cavity lesions and control group should be analyzed for significant evidence. Based on the cases observed in this study I would suggest all readers to carefully assess the oral cavity lesions and use FNA biopsy for early diagnosis of suspicious lesions.

Strength of Recommendation Taxonomy (SORT) Grading

LEVEL OF EVIDENCE:

Level 3: Other evidence

STRENGTH OF RECOMMENDATION GRADE:

Grade C: Consensus, disease-oriented evidence, usual practice, expert opinion, or case series

for studies of diagnosis, treatment, prevention, or screening.

NIH Rating: 6

Works Cited

1. Richard C. Cardoso & Peter J. Gerngross & Theresa M. Hofstede & Donna M. Weber & Mark S. Chambers. The multiple oral presentations of multiple myeloma. Support Care Cancer (2014) 22:259–267 DOI 10.1007/s00520-013-1960-y.