Meliodosis, also called Whitmore’s disease, was first discovered in 1912. This infectious disease is an endemic in Southeast Asia and Northern Australia, and it has a high mortality rate (Cheng and Currie, 2005). The mortality rate of meliodosis in Thailand is approximately 40% and 15% in Australia (Limmathurotsakul and Peacock, 2011). Meliodosis is caused by Burkholderia pseudomallei, a gram-negative saprophytic bacterium capable of living in hostile conditions such as lack of nutrients, both acidic and alkali environments, and a wide range of temperatures. In Thailand, B. pseudomallei is responsible for 20% of community-acquired septicemia (Cheng and Currie, 2005). Current treatment options are expensive and extensive (CDC, 2012). Without
In her book, Dorothy Crawford gives biographies of the history of microbes which have brought humans diseases on a large scale. These include epidemics like yellow fever, tuberculosis, smallpox, acute respiratory syndrome, bubonic plague, syphilis HIV, the Black Death, malaria and cholera. It is worth to point out that her work is up to date because most of these microbes are still with us in this era. Crawford uses the historical bibliography of humans experience with microbes to show a fact that microbes shaped our culture through infection, disease, and pandemic. At the same time, the ever changing human culture has also largely influenced the evolutionary nature of microbes.
Mat Johnsons novel, Pym challenges readers not only to view his work with a new set of eyes but also the work of all American literature with the understanding that the idea of Whiteness still has a very strong power over literature today. It is unfortunate that in today’s society, the pathology of Whiteness still holds a very strong presence in literary world. Literature from American authors versus literature from African American authors still continues to be segregated and handled with two different sets of criteria. Johnson’s novel engages in different aspects of the argument presented in Toni Morrison’s work entitled Playing in the Dark: Whiteness and the Literary Imagination. One of the main ideals that Pym engages in is the thought that “…a figuration of impenetrable whiteness … surfaces in American literature whenever Africanist presence is engaged” (29). Through the character Chris Jaynes, Johnson’s novel focuses much attention on the Whiteness seen in the literary world and how it still affects literature today. Mat Johnson’s Pym addresses Morrison’s argument by challenging the reader to identify the pathology of whiteness as well as encourages readers not to only identify the problem but try to find new ways to combat it.
Flaccid dysarthria results from damage to the lower motor neurons (LMN) or the peripheral nervous system (Hageman, 1997). The characteristics of flaccid dysarthria generally reflect damage to cranial nerves with motor speech functions (e.g., cranial nerves IX, X, XI and XII) (Seikel, King & Drumright, 2010). Lower motor neurons connect the central nervous system to the muscle fibers; from the brainstem to the cranial nerves with motor function, or from the anterior horns of grey matter to the spinal nerves (Murdoch, 1998). If there are lesions to spinal nerves and the cranial nerves with motor speech functions, it is indicative of a lower motor neuron lesion and flaccid dysarthria. Damage to lower motor neurons that supply the speech muscles is also known as bulbar palsy (Pena-Brooks & Hedge, 2007). Potential etiologies of flaccid dysarthria include spinal cord injury, cerebrovascular accidents, tumors or traumatic brain injury (Pena-Brooks & Hedge, 2007). Possible congenital etiologies of flaccid dysarthria include Moebius syndrome and cerebral palsy. Flaccid dysarthria can also arise from infections such as polio, herpes zoster, and secondary infections to AIDS (Pena-Brooks & Hedge, 2007). Additionally, demyelinating diseases such as Guilian-Barre syndrome and myotonic muscular dystrophy can also lead to flaccid dysarthria (Pena-Brookes & Hedge, 2007). The lower motor neuron lesion results in loss of voluntary muscle control, and an inability to maintain muscle tone. Fasciculations, or twitching movements, may occur if the cell body is involved in the lesion (Seikel et. al., 2010). The primary speech characteristics of flaccid dysarthria include imprecise consonant production, hypernasal resonance, breathiness, and harsh voice (...
The clinical should look for the symptoms that might help him to identify the diagnosis of client. As Meredith mentioned that she cannot sleep and eat properly it is necessary to find out changes in her appetite and weight. Meredith also mentioned that she cannot work properly, so the clinical should ask about problems with concentration. The symptoms of Meredith case seem to be similar to depression, so the clinical should ask about suicide thoughts, thoughts about death and worthlessness; the frequency of such thoughts should be considered. Meredith also should be asked if she feels tired or exhausted easily as it also can point out that she is deeply depressed. is The clinical should ask about mood alteration during the day and define what does it depend on. Also Meredith should be asked about muscle tension as it points out anxiety disorder.
Pseudomonas aeruginosa (P. aeruginosa) is a gram-negative, rod-shaped aerobic bacterium. It is a primary cause of hospital-acquired infections. P. aeruginosa is primarily a nosocomial pathogen. It also acts as an opportunistic pathogen, which can only infect a host that is immunocompromised, due to an underlying disease or medication. Although, P. aeruginosa can cause damage to virtually any tissue in the body, it almost never affects the tissues of healthy individuals. It is a problematic pathogen in hospitals; infecting individuals with cancer, burn wound, catheters and cystic fibrosis. P. aeruginosa is most recognized for its resistance to a wide range of antibiotics. In its planktonic form, P. aeruginosa has been found to have many virulence factors. However, P. aeruginosa within biofilms have been found to have a resistance to antibiotics 1,000 times greater than that of its planktonic counterparts [4]. Infections that are caused by bacterial biofilms are very persistent and very difficult to treat.
I have chosen to do this research paper on a very rare disease that directly affected my family. My Husbands Uncle, at the young age of 54, was diagnosed with Wegener’s Disease and survived only six short months from the time of his diagnosis. He was severely ravaged by the disease by nearly every symptom that I will explain further in this research paper.
Addison’s disease is a disorder of the endocrine system. It is a hormonal disorder that can strike anyone, any gender at any age. Addison’s disease has also been called Adrenal Insufficiency (hypocortisolism) because the root of the disease is in the adrenal gland not producing enough of the hormone cortisol, or sometimes not enough of the hormone aldosterone to satisfy the body’s needs.
Wolff-Parkinson White syndrome is a heart condition where there is an extra electrical pathway or circuit in the heart. The condition can lead to episodes of rapid heart also known as tachycardia. Wolff-Parkinson White syndrome, also known as WPW, is present at birth. People of all ages, even infants, can experience the symptoms related to WPW. Episodes of tachycardia often occur when people are in their teens or early twenties. Most of the time, a fast heart beat are not life threatening, but serious heart problems can occur. Treatments for Wolff-Parkinson White syndrome can stop or prevent episodes of fast heart beats. A catheter-based procedure, known as ablation can permanently correct the heart rhythm problems.
Simple infections are no longer death sentences, however, immunities to these antibiotics are appearing. The use of antibiotics save lives by crippling the ability of bacteria to damage the human body, and antibodies act as a sidekick to the immune system when fighting off life-threatening illnesses. In “The Life of a Peasant”, William Stearns Davis (1922) focuses on what life would be like for the lowest tier of people in a feudalistic state, and he concluded that often in a world without antibiotics, people lose their lives to easily preventable medical conditions, regardless of whether they are a king or a peasant. Antibiotics are used to fight infections that could otherwise prove deadly. In a time before antibiotics, life was much more difficult for all involved. Before antibiotics were used, many died of simple cuts or scratches that later got infected. If action is not taken, superbugs could grow immune to all of the antibiotics we possess. Superbugs are becoming immune to the ways we fight them, which forecasts a world without the ability to fight these superbugs. In the article “Superbugs Causing Infections at a Tertiary Care Hospital and the Return of Pre-Antibiotic Era!” Kalyan Rajkumar (2016), associate professor of microbiology at King George 's Medical University, as well as his research team, discusses the prevalence of a strain of E. coli that is mostly immune to the majority of current
"Bloodborne Pathogens : MedlinePlus Medical Encyclopedia." U.S National Library of Medicine. U.S. National Library of Medicine, n.d. Web. 09 Feb. 2014.
Cyclothymic disorder, also known as cyclothymia, is a relatively mild form of bipolar II disorder characterized by mood swings that may appear to be almost within the normal range of emotions. These mood swings range from mild depression, or dysthymia, to mania of low intensity, or hypomania. It is possible for cyclothymia to go undiagnosed, and for individuals with the disorder to be unaware that they have a treatable disease. Individuals with cyclothymia may experience episodes of low-level depression, known as dysthymia; periods of intense energy, creativity, and/or irritability, known as hypomania; or they may alternate between both mood states. Like other bipolar disorders, cyclothymia is a chronic illness characterized by mood swings that can occur as often as every day and last for several days, weeks, months, or as long as two years. Individuals with this disorder are never free of symptoms of either hypomania or mild depression for more than two months at a time (Encyclopedia of Mental Disorders).
Over the years humans have tried every possibility to overcome the health problems, spread of epidemics and infections, disease control and have worked towards a healthy society free of disease and health problems. They have succeeded to a great extent. The book “Good germs, bad germs” describes that though the life expectancy is now far more as it was in previous eras. Epidemic problems and infectious diseases are now getting lesser and lesser and humans are being treated successfully. The hygienic conditions have also been improved so as to ensure least growth of microbes, germs, parasites and bacteria. Antibiotics have been invented to address diseases and infections caused by bacteria and viruses. With all these substantial efforts the biologists, physicians and scientists have triggered another epidemic which is even more severe. They have killed those microbes and bacterial species which were human friendly and as a result of either their disruption or mutation, pathogenic bacteria have even become more active and resistant to treatments. This has led to increased ineffectiveness of antibiotic drugs, low immunity and various infections and inflammatory diseases. The chlorinated water for drinking and food processing along with excessive hygienic conditions indicates our fight against these bacteria and germs. Further, these antibiotics are even given to the livestock which becomes our food and as result many of their resistant germs end up in our digestive tract and other organs. Thus, the war against microbes through excessive cleanliness and use of antibiotics has resulted in antibiotic resistance among humans, which has become one of the prominent problems of medical science
In the documentary, Hunting the Nightmare Bacteria, reporter David Hoffman investigates this new untreatable infection along two individuals and a bacterial virus within a hospital. The first individual Hoffman investigates is Addie Rerecich of Arizona, she was treated for a staph infection with antibiotics, but other complications arise. Addie had a lung transplant, she was given several different antibiotics, but her body became pan-bacteria, non-resistance to the bacteria. Addie’s life was on the edge, she had to be on life support, and finally she received new lungs. The transplant helped Addie but it would take years before could go back to normal before the infection. The second individual is David Ricci; he had his leg amputated in India after a train accident. The antibiotic treatment he received became toxic to his body increasing problems. While in India, he underwent surgery almost every day because of infections he was developing. Back in Seattle, doctors found the NDM-1 resistance gene in his body; NDM-1 gene is resistance to almost all antib...
The word melanoma comes from the Greek words, melas (black) and -oma (tumour). It is a very serious cancer that most often occurs in the skin and less frequently in the eye or in the lining of the nose, mouth, or genitals. Melanoma begins in melanocytes, cells that make a pigment called melanin. Both light- and dark-skinned people have melanin, which gives colour to the skin, hair, and parts of the eye.
“Recreational water illnesses (RWIs) are caused by germs spread by swallowing, breathing in mists or aerosols of, or having contact with contaminated water in swimming pools, hot tubs, water parks, water play areas, interactive fountains, lakes, rivers, or oceans. RWIs can also be caused by chemicals in the water or chemicals that evaporate from the water and cause indoor air quality problems. RWIs may include a wide variety of infections, including gastrointestinal, skin, ear, respiratory, eye, neurologic and wound infections. Many RWIs (skin, ear, eye, respiratory, neurologic, wound, and other infections) are caused by germs that live naturally in the environment (for example, in water and soil)” (Centers for Disease Control and Prevention).