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Essay on recombinant DNA technology
Essays over performance enhancement drugs
Benefits and hazards of recombinant DNA technology
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Ryan Vu
EPO (Draft)
Lance Armstrong is one of the most recognized athletes of the 20th century. He is well known for his seven Tour de France victories. It is one of the most famous and rigorous cycling competitions because of its length, which is over 1,000 miles. It is a huge accomplishment to win just a single Tour de France, but his feat has never been repeated. As he rode triumphantly in his yellow jersey drinking champagne through Paris, he was glorified for his accomplishments. Many people were idolizing him since it was an unimaginable feat. Despite his denial, rumors were spread that he was using performance-enhancing drugs. After years of innocent claim, he finally admitted to doping. One of the drugs that he used was EPO. Many people were unaware of the drug until Lance Armstrong admitted to using it. The substance allowed his body to produce more red blood cells, thus increasing his oxygen carrying capacity and significantly increased his endurance. However, EPO has been very useful to sick patients in need red blood cells. Despite the abuse of EPO by athletes, it can also help patients with a variety of diseases, and therefore the benefits outweigh the risks.
Genetic engineering is defined as the direct manipulation of genes for practical purposes (citation). It is modifying an organism’s genome using biotechnology (citation). An example of genetic engineering is recombinant DNA technology, which is using DNA from two different sources (citation). This means you can insert the DNA from one species into another in order to make useful proteins. This technology can be used to develop useful human proteins. Some proteins that have been made from recombinant DNA technology are insulin, HGH, Ce...
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...at is injected cannot be distinguished from natural EPO that is produced in the body. Also, any EPO would be undetectable in the urine after 3-4 days. Cyclists either use just enough so it’s undetectable, or use saline to thin their blood.
In conclusion, the use of genetic engineering is very useful, as it can produce many products that can benefit us in many ways. Examples of this include genetically engineered crops that last longer, and are more nutritious, as well as medication that can be mass-produced. Using recombinant DNA technology, EPO was mass-produced in hamster ovarian cells, which aids patients suffering from anemia due to IBD, and chemo or radiation therapy. Even though athletes, such as Lance Armstrong, abuse it in order to cheat, the advantages of helping millions of people far outweigh the disadvantages and should continue to be produced.
The use of erythropoietin (EPO) by athletes in recent years has made the headlines of
Yesalis, C.E. Anabolic Steroids in Sport and Exercise. (2nd Ed.) 2000. Human Kinetics, United States.
...ackdate a prescription for corticosteroids for a saddle sore to explain a positive steroid test result” ( Sinnott). Because Armstrong’s desires to win at the Tour de France, he chose to take steroids to make himself more powerful than his competitors. This is similar to how some businesses cheat by creating monopolies in order to control all the money. Armstrong is like those corporations that make the choice to be more powerful but is morally unethical because it causes inequality of opportunity to others around them.
Throughout this essay five points have been presented which highlighted what Erythropoietin is, how it works, what its benefits are compared to its potential side effects and its overall use in professional sport. Its function as a red blood cell producer and regulator are essential to ensure that our muscles, organs and brain have enough oxygen and nutrients flowing into it at all times. The invention of an artificial version of Erythropoietin has ensured a viable treatment for some conditions but has also opened up the possibly of unethical use in sports. The health risks incurred with use of r-HuEPO especially in the long term mean that its risks far outweigh any minor perceived benefit for athletes and as such should only be used for prescribed medical reasons.
The question of drug use among athletes in what was previously considered by the unknowing public to be a rather pristine sport, cycling, is important in that it will affect all future Tours and will place them and the athletes under scrutiny. To begin with, in Europe until the 1998 scandal occurred, despite a few exceptions, cycling was considered a drug free sport. The 1998 drug scandal tarnished the Tour de France and the reputation and image of other sports. The media response to the scandal took differing positions on what should be done next to clean up cycling. The scandal also affected advertisements, sales, and without question the 1999 Tour and Lance Armstrong. Since even the most naïve fan no longer trusts the cyclists, drug-testing procedures have been instituted. Also, the question now arises regarding medications used by seriously ill cyclists.
In September 14, 1990, an operation, which is called gene therapy, was performed successfully at the National Institutes of Health in the United States. The operation was only a temporary success because many problems have emerged since then. Gene therapy is a remedy that introduces genes to target cells and replaces defective genes in order to cure the diseases which cannot be cured by traditional medicines. Although gene therapy gives someone who is born with a genetic disease or who suffers cancer a permanent chance of being cured, it is high-risk and sometimes unethical because the failure rate is extremely high and issues like how “good” and “bad” uses of gene therapy can be distinguished still haven’t been answered satisfactorily.
Genetic engineering is now being used to create new medicines and therapies for many disorders and diseases, and also to improve agricultural plants and animals to produce bigger yields or enhanced nutrient composition and food quality. In Gene therapy, copies of healthy human genes produced in bacteria can be inserted into human cells with defective or missing genes, to fix the problem. Gene therapy is promising because it can use to treat genetic
Genetic engineering has been around for many years and is widely used all over the planet. Many people don’t realize that genetic engineering is part of their daily lives and diet. Today, almost 70 percent of processed foods from a grocery store were genetically engineered. Genetic engineering can be in plants, foods, animals, and even humans. Although debates about genetic engineering still exist, many people have accepted due to the health benefits of gene therapy.
International Association of Athletics Federation (IAAF)"Drugs in Sport/Doping Control," IAAF Medical Manual, www.iaaf.org (accessed May 13, 2009)
Wilson, Jacque. "Lance Armstrong's Doping Drugs." CNN. Cable News Network, 18 Jan. 2013. Web. 12 July 2013.
This is to prevent the chance that their samples would be tampered with, compared to if the drug test was announced, meaning that athletes would have had enough time to plan their potential tampers. For some time, FINA had trouble trying to locate Smith for the drug test, finding that she was consistently unavailable, or just could not get to her front door. But on January 10 1998, Smith was greeted with a spontaneous drug test in her home. Four to six minutes after FINA’s arrival, Smith returned with a urine sample. But after testing conducted in a laboratory, not only was the sample found to be tampered with with whiskey, but traces of androstenedione were found too. By diluting the urine sample with alcohol, Smith was able to hide any usage of other Performance Enhancing Drugs. By taking the steroid of androstenedione, the body produces more testosterone and oestrogen. This hormone helps produce more strength, and improves endurance, meaning swimmers could swim stronger, but also for longer. Providing an increase in red blood cell production, more oxygen is then sent around the body, also aiding the swimmer swim for longer periods of time. Additionally, androstenedione improves stamina, and increases muscle size. The hormone also has the ability to minimize the mass of fat, paving a way for increased muscles. Furthermore, androstenedione helps in muscle
Lance Armstrong is known for his seven Tour De France road cycling titles. Because of his actions involving steroid use, all of those titles were taken away. After Lance battled off testicular cancer, he founded a foundation named the Lance Armstrong Foundation for Cancer (“Armstrong”). This foundation is now called LiveStrong. After Lance ran in the New york marathon, he helped raised 600,000 dollars towards his foundation (“Armstrong”). In October of 2012, Lance stepped down from LiveStrong after the USADA filed a report about Lance Armstrong’s abuse towards performance enhancing drugs (“Armstrong”). With Lance Armstrong confessing to using performance enhancing drugs, it could possibly lead to more people confessing of the use of steroids which could end up in decreasing the amount of people that you performance enhancing drugs. Lance Armstrong also had a hard time with the effects of the performance enhancing drugs in a mental way. At first lance Armstrong denied that fact that have had used steroids, he later admitted to it, but after he admitted, his medals were taken away from him, and his seven Tour de France titles (“Armstrong”). All of Lance Armstrong’s fans were let down when they heard the unsatisfying news that Lance had been doping his way to victory. It is terrible to think that way and I'm strong did not think that his
As the use of PEDs is becoming more common, controversy over the legalization has emerged. Among the many different types of performance enhancing drugs out there, the common ones consist of: steroids, red blood cell doping, and human growth hormone. Lance Armstrong was convicted of red blood cell doping and has been stripped of his title and banned from professional cycling. With the numerous amount of athletes convicted of PED abuse, one can question if it is a problem with the athletes or if it is a problem with the state. In all professional sports in the United States, the use of PEDs is prohibited.
Dr Kare, Birkerland, I Hammersbach, P. . (July 1999). The future of doping control in athletes . Sports medicine . 28 (1), 25-33.
Before being used on humans it was used on crops to enhance the livestock to increase taste size and many other desirable traits in food to make them more enticing to consumers and to make them easier to grow in certain weather conditions and also to withstand pesticides needed to safeguard the crops. There is not any proof of the long term effects of genetic engineering. People have been worried about the effects of eating genetically engineered crops on their health and because of the concern the Organic Trade Association doesn’t allow genetically altered.