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Recommended: Thesis on thalidomine
The use of Thalidomide started in 1957 in Germany. It was developed by a German company. It was on the market, from January 1957- December 1961. Once it came out in the stores it became popular in Europe and Germany as aspirin. The bottle that read STRICT WARNING: DO NOT TAKE IF PREGNANT! many still did because they thought it would help with the side effects of being pregnant. It also said DO NOT give to children under twelve years old, but, the mothers still did. Shortly after the debut of this drug more than 2,500 children were born with limbs that were not fully developed. Out of 2,500 children only 466 children survived.The women would take this drug in their first trimester, and so that is why the children were born they way they were. Once the children were born the Thalidomide …show more content…
http://multinationalmonitor.org/hyper/issues/1987/04/thalidomide.html. The lesson that they learned was always read the label on bottles and don’t just assume that it will help you with the side effects or for being pregnant. They would die from one thing that their mother did when she was pregnant. Now, it’s a good thing they took Thalidomide off the market and got rid of it forever because we would have more and more people die or have defected limbs and get bullied at school or any place. Another reason it is good that we do not have Thalidomide is because there would be more accidents if people are born with their arms and legs close to them. They would have to sit close to the steering wheel and have a long stick type thing to help the must the gas and break. http://www.bbc.com/news/magazine-15536544. http://www.thalidomide.ca/recognition-of-thalidomide-defects/ Finally, Thalidomide is no joke it can kill little innocent kids even their mother too. No one should have to go through the death of a little kid that was just born or even a few months old. Thalidomide should never be made again in any part of the
Two weeks after he was discharged the baby who had received SimplyThick was readmitted, according to Saint Louis (2013) because of a distended abdomen and what seemed to be inconsolable pain. Soon after he was readmitted the baby passed away from NEC. A month after the incident the U.S. Food and Drug Administration (F.D.A.) issued a statement about SimplyThick stating that it should not be give...
was approved in 1982 and in another form, that is to be taken orally rather than
...s little information about the possible benefits of the study or the side effects. The side effects proved to be significant (gastrointestinal complains, headache, and an elevation of alanine aminotransferase), while the benefits were minimal. This situation emphasizes the need for a balanced approach when it comes to drug clinical trials.
Modern birth control pills were approved by the FDA in the 1960s. This was heralded
for example, the animal testing that allowed the drug to be produced never included testing on animals who were pregnant, so they had no idea of the side effects this drug would cause on pregnant women. However, despite this lack of medication testing the drug was still placed on the German market in 1957, thalidomide was marketed as an over the counter prescription and was advertised as being “completely safe” while falsely emphasizing its safety “even during pregnancy” although they had never tested the medication during
Although birth control has been practiced since ancient times, the first organized efforts developed during the 19th century as population increased dramatically because of improved medical care, nutrition, and sanitation. However, birth control met with resistance. In 1873 the United States Congress enacted the Comstock Law, which prohibited the distribution of birth-control devices and information.
defects. They will remain in intensive care for weeks or months after their birth. Their
There was a feud between feminists who wanted flibanserin regardless of the side effects, and FDA who believed the approval for safety of flibanserin was an elongated process. This paper will explain the six reasons why flibanserin had been mistakenly approved by FDA.
Birth control has been a controversial topic from the beginning of time till now. Some of the world stands against the use of birth control methods and medications all together while others think it is one of the greatest things ever invented. Some families, groups, religions, and other countries define birth control as abstinence or not having sex until marriage. Birth control’s other leading definition is using medication to prevent pregnancy. Different methods of birth control are as simple as the withdrawal or pulling out before ejaculation method. Others are more complicated like the Nuvaring, vaginal ring, or Mirena which are placed inside the vagina. There are various types of birth control options on the market today, but one of the oldest and most reliable, used by women every day, is oral contraceptives or birth control pills. Oral contraceptives have been developed to help prevent pregnancy along with combating other things such as cramps, bloating, and some even help with acne and mood swings. Due to the various ways birth control pills can help women they have become extremely popular. Amongst the different types of birth control pills Yaz has arisen in the last ten years as one of the most popular on the market. However, just because it is popular does that make it safe to use? Negative reports have surfaced about what Yaz is made of, lawsuits, deaths, and the Food and Drug Administration’s (FDA’s) involvement with the Bayer Company the makers of Yaz.
Thalidomide is a sleeping sedative (The First Appearance Of Thalidomide, n.d.). The drug was “similar to barbiturates with relatively low known toxicity in adults (Breaking News Thalidomide, n.d.)”. Thalidomide was marketed as safe for pregnant women, who used it to combat morning sickness (The First Appearance Of Thalidomide, n.d.). The drug was developed by West German Pharmaceutical Company, Chemie Grünenthal GmbH, because the company wanted to expand the antibiotics it produced (The First Appearance Of Thalidomide, n.d.). “It was an inclusive anti-convulsive drug” (The First Appearance Of Thalidomide, n.d.). Thalidomide is absorbed in the gastrointestinal tract and metabolized through a no enzymatic pathway, undergoing spontaneous
The continuous introduction of new drugs into the pharmaceutical world proves to have immense benefits to society’s treatment of medical issues, however it has also proved to cause disaster. A seamless example of the often terrible events that occur due to quickly advancing medicine is the disaster caused by the drug Thalidomide in the late 1950’s to the early 1960’s. Thalidomide was taken by thousands of pregnant mothers to battle symptoms of morning sickness. It is estimated that ten to twenty thousand babies were born with serious disabilities and physical defects due to this seemingly harmless drug. As researchers are finding new uses for the drug, controversy has arisen whether
However, regardless of the outcome, thalidomide is proven to affect our health. In the 1960’s, thalidomide was one of the most dangerous pharmaceuticals on the market. It started off as a drug, prescribed to mothers experiencing mild or severe morning sickness as a result of their pregnancies. It was later discovered by toxicologists that thalidomide was a teratogen. The most common effect of thalidomide to the embryos was peripheral neuropathy (See figure 3). This is a disorder is the result of damage to your peripheral nerves, and often causes weakness, numbness and pain, usually in one’s hands and feet (Mayo Clinic, 2017). Peter G. Wells, a scientist who specializes in toxicology concluded from his extensive research on thalidomide that the reason it causes birth defects, including peripheral neuropathy, is because is breaks down. He discovered that once a small dose of thalidomide has been ingested, it breaks down into many different compounds, which last approximately 40 times longer than thalidomide itself. These compounds ultimately lead to the production of highly toxic forms of oxygen, called "reactive oxygen species," (ROS) including hydrogen peroxide and free radicals that alter disrupt normal embryonic development, causing birth defects (Federation of American Societies for Experimental Biology, 2011). Thalidomide negatively impacted a mother's health because it invades the embryo and causes mutations to the genes of the limbs. Thalidomide is also a neurotoxin because peripheral neuropathy causes severe pain and stabbing sensations that are altered signals from the brain to the limbs, causes by the compounds that break down from the initial
Stubblefield, P. "Self-Administered Emergency Contraception -- A Second Chance." 339 New England Journal of Medicine 41 [July 2, 1998].
Unfortunately they made the decision to essentially end their child’s life. One can assume they chose this because of his mental disability which is extremely unethical in our society today. There was a similar story that made headlines in 1982 when a boy was born with downs syndrome and a tracheoesophageal fistula. The parents of the child decided to refuse surgery for their newborn baby and it resulted in the baby dying of dehydration (White, 2011). This caused an uproar and there was a revision made to the Child Abuse Prevention and Treatment Act that made physicians able to make medical decisions for infants even if the parents do not concur (White, 2011).
There are many other options and treatment plans for people to consider before handing their life over to drugs. Drugs are not meant to be legalized without proper information and education about the drug for the public. Educational programs in the school system are a way of teaching the youth of how harmful these substances are. Even though some may be effective in treating pain, there are long-term side effects associated with these drugs that people need to consider. Pain is inevitable and suffering is