Randomised Controlled Trial

783 Words2 Pages

In this article the authors have undertaken a cluster randomised controlled trial (RCT), unblinded, with 79 general practices in England participating, involving 2,142 patients. Of interest, originally, 41 practices had shown interest in this trial, 15 of these practices already had nurse-led clinics and so were ineligible to participate. With respect to the trial, there was a comparison of three groups of patients with coronary heart disease in primary care: an audit group, a GP recall group and thirdly a nurse recall group. The primary outcomes of the trial were associated with three risk factors: blood pressure (BP) and cholesterol levels, together with ascertaining smoking habits. Secondary outcomes were related to anti-hypertensive, …show more content…

Findings included an improvement in assessment of all three risk factors especially cholesterol levels in the GP and nurse recall groups. Yet there were insignificant differences in risk factor reduction. Secondary outcomes varied with all groups having increased prescriptions for lipid lowering medication; minimal change in the prescription of anti-hypertensives and an improvement in the prescription of anti-platelet medication in the nurse recall group only. As quality of life tools were used rather than a total focus on medication adherence, I consider this added a more holistic basis to the trial. Given would the advent of nurse prescribers is a relatively new occurrence, I wander if this would have made even more of a difference to the groups. In conclusion, follow-up care by nurses is as effective if not better than doctors. This journal article does partially supports the proposed research question but only addresses three modifiable risk factors and is not specific to symptom …show more content…

(Neil Crawford Campbell et al., 1998) Four years later, patients were followed up. (P. Murchie, Campbell, Ritchie, Simpson, & Thain, 2003) On both occasions, research demonstrated the benefits of attending nurse-led clinics for the secondary prevention of CHD. The article I have chosen to annotate is the 10 year followup of the original RCT. Given the time incurred, I consider the accumulated data as strong evidence that has being reviewed and evaluated vigorously. There were only a few other studies that showed long term results, two – five years, regarding the use of nurse-led clinics for the secondary prevention of CHD. (Cupples & McKnight, 1994; Moher et al., 2001) Total mortality was less and survival of coronary events had been better, though statistically insignificant in the nurse-led group. At the 10 year follow-up, survival of coronary events, results graphically converge. Otherwise the study indicated that overall the GP and nurse-led group results were similiar for total mortality, other causes of death, coronary death and hosptial admissions for cardiac events. This research supports the notion that nurse-led clinics convincingly are as effective as seeing a Doctor for the management of symptoms and reducing cardiovascular risk

Open Document