Rabies Research Paper

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Introduction Rabies is one of the oldest known infectious diseases known to man. Its historical background is related to the rise of civilizations, the growth of cities worldwide, and the contact with wildlife and the domestication of different kinds of animals. The term “rabies” has been around since 3000 B.C., with the name being Latin for “fury”, “madness”, and “rage” (Williamson, 2010). Consequently, rabies have infected many animals and humans for thousands of years, and in this essay rabies will be further evaluated. Topics relating to rabies, such as its causative agent, epidemiology, transmission, clinical features, diagnosis, treatment, prognosis, and control measures will be discussed in order to further explain the gruesome …show more content…

The causative agent of rabies is the rabies virus, which has helical symmetry with infectious particles that are cylindrical in shape (Williamson, 2010). The cylindrical shape of the rabies virus gives it a striated appearance, and are surrounded by bullet-shaped envelopes. The rabies genome encodes five proteins: nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G) and polymerase (L). The arrangement of these proteins and the RNA genome determine the structure of the rabies virus. (“The Rabies Virus”, …show more content…

The diagnosis or animals can be determined by taking any part of the infected brain, but it has to be taken from the brain stem and cerebellum. There are many diagnostic tests from animals, such as mouse inoculation technique, tissue culture infection technique, direct fluorescent antibody, and polymerase chain reaction (Yousaf, 2012). Clinical diagnosis of rabies is divided by three stages; prodromal, excitement, and paralytic (though not all of these stages can be observed in an individual). The initial clinical symptom is neuropathic pain that is located at the site of infection or wound due to viral replication. After the prodromal phase, either the excitement stage, the paralytic stage, or both, of the disease may be observed in the particular species (Yousaf, 2012). In the United States, the results of a rabies test are typically available within 24 to 72 hours after an animal is collected and euthanized. Roughly 120,000 animals or more are tested for rabies each year in the United States, and approximately 6% are found to be rabid (“Diagnosis”,

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