Psychoneuroimmunology (PNI)

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Remember as a child when your parent would yell to you repeatedly, “you worried me sick”, or “scared to death”? Linguistically speaking, emotion and physiology have been connected for ages, yet it took science a little longer to catch on. Psychoneuroimmunology (PNI), is a multidisciplinary approach to examining the interconnections of the mind-body experience. More specifically it incorporates neurology, immunology, and endocrinology with behavior to analyze the body’s physical reactions to emotion states on the molecular and system level. PNI is a relatively immature science, but its contributions are far reaching, especially to the field of nursing. Every nurse knows the importance of the immune system in maintaining homeostasis within …show more content…

It is a complex interaction of immune inhibition and activation, balanced by the sympathetic and parasympathetic nervous system. “PNI is focused on this interaction of behaviors, emotions, psychological responses, the central nervous system, and the immune system, and how these interactions can lead to illness or wellness” (Clark, 2014). Take the “worried sick” phrase. Acute stress, such as that experienced when your child does not return home by their curfew, is shown to release hormones such as cortisol as well as neurotransmitters that activate the body’s flight or fight response of the sympathetic nervous system. Both pathways have shown to lead to permeant tissue damage if frequent or prolonged, as well as immunosuppression (Clark, 2014). By missing curfew, the child could contribute to their parent’s development of heart disease or …show more content…

Simplistically, it is about finding order in the unstable, non-repetitive behavior of a continuous, nonlinear system. The theory “provides insight and guidance into the delicate and shifting relationship between order and disorder in ways not permitted in modern science nor imagined in more traditional knowledge processes” (McEwen & Wills, 2014, p 296). There are two basic principles guiding this theory. First, systems are essentially orderly disorders, meaning they use nonlinear behaviors to strive for stability and order. Secondly, seemingly small change can cause complex and drastically different behaviors (McEwen & Wills, 2014, p 296). To understand this first principle, take common arrhythmias seen in the emergency room: second degree AV block. It is often labeled as regularly irregular rhythm. It is not a normal heart rhythm where a QRS follows every P wave on an EKG, instead there is a gradual lengthening of the PR interval, with eventual dropping of the P wave (dropped beat). Although it presents an irregular cardiac rhythm, there is a pattern to that irregularity. The cardiac rhythm is displaying a nonlinear behavior (PR interval and dropped P wave) in an attempt for stability and order (producing a contractual beat of the

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