Primary Anabolic Hormones

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Primary Anabolic Hormones and Resistance Training
Anabolic hormones are chemical messengers that promote the growth of muscle tissues. There are three primary anabolic hormones: testosterone, growth hormone (GH), and insulin-like growth factors (IGF).1 Testosterone is an androgen hormone that is secreted by the testes in men and ovaries and adrenal glands in women.1 This hormone interacts with the nervous system and assists in stimulating protein synthesis, inhibiting protein degradation, and allowing for muscle hypertrophy. 1, 2 In males, testosterone levels are highest in the mornings and wane throughout the day; however, there is a lower concentration of testosterone with limited variation in women throughout the day.1 Intensity, volume, …show more content…

The anterior pituitary gland secretes GH, also called somatotropin, and it is vital for child development and adaptation to the stresses from resistance training.1 The concentration of GH changes depending on the time of day, but during sleep, the concentration is at its highest.1 The effects of GH is also facilitated by the production if IGF which may require 8-29 hours to produce.1 In daily life, factors such as sleep, diet, and gender dictate the pattern at which GH is secreted.1 Similar to testosterone, intensity, rest and volume affect GH response during resistance training.2
IGF is secreted from the liver, and there are two types of IGF: IGF-I and IGF-II which are both polypeptides, but IGF-I is a 70-amino acid and IGF-II is a 67-amino acid.1 Testosterone and thyroid hormones also regulate IGF synthesis.1 Nutrition and insulin levels aid in signaling the release of IGF.1 The response of IGF is related to the amount of initial concentraions.1 For example, if initial consecrations are low, IGH-I levels increase and if the initial concentrations are low, IGF-I levels decrease or remain the …show more content…

There is conflicting research regard the effect of short vs. long rest duration in testosterone response. One research reported that testosterone response is not affected by the duration of rest while another reported that shorter rest period of one minute resulted in a higher concentration of testosterone compared to a long three minute rest duration.2
In Ho and colleague’s study, low- intensity resistance exercise resulted in significantly increased levels of GH.3 However, in the National Strength and Conditioning Associaton’s Essentials of Strength Training and Conditioning, low-intensity resistance training with high reps resulted in a lack of change in GH response. It is believed that there is an intensity threshold that must be attained in order to have a change in GH concentration.1 High intensity incorporated with short rest periods resulted in an increase in levels of GH

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