Outer Hair Cell Function

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The Organ of Corti houses both inner and outer hair cells located on the medial and lateral sides of the tunnel of Corti, which is composed of pillar cells. For humans, there is one row of inner hair cells inside each cochlea numbering approximately 3,500. As for outer hair cells, there are three to five rows and are approximately 12,500 in each cochlea. The inner and outer hair cells are different in their structures, which indicates that their functions will most likely differ as well.

Outer hair cells are cylinder-shaped, which is appropriate for expansion and contraction. The outer hair cells measure about 10 m in diameter, and the length of the outer hair cells vary. In the apical area of the basilar membrane, which is tuned for low frequencies, …show more content…

They have a stiffness gradient, and vary in length from the base to apex. These fibers help tune the frequency specificity of the tonotopic organization of the cochlea. Stereocilia are connected by tip-links and cross-links. Tip-links are small filaments that connect to other cilia and hair cells. When tip-links that are connected to the tops of other stereocilia deflect, they allow channels to open and potassium ions rush into the hair cell. Cross-links are structured like tip-links, connected to cilia, and help the cilia move in unison upon deflection. The hair cells are tuned along the length of the basilar membrane. The hair cells that are located at the base end of the cochlea respond to high frequency sounds, and those at the apex respond to low frequency sounds. When stereocilia or the hair cells become damaged, it causes disruption in the auditory signal, and can possibly result in hearing loss. The outer hair cell stereocilia are often the first structures damaged by high-intensity noise exposure. Hair cells also have a characteristic frequency, which is the frequency at which the hair cell best responds. Based on the tuning features of the cochlea, we know that the characteristic frequencies of the hair cells decrease as one moves from the basilar to apical end of the cochlea. A cochlear hair cell is sensitive to a specific range of frequencies that are higher and lower than the characteristic …show more content…

Hair cell transduction is a major part in the hearing method, by converting mechanical vibrations into electrical activity. The elaborate structures and specific roles for the thousands of inner and outer hair cells, in each cochlea, are essential to hearing. The auditory process would not work coherently, as it does in normal hearing individuals, if it were not for the multiplex functions of these hair cells. Without hearing your communication is limited and with limited communication the individual

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