Mapping the Human Genome Vision- In the past, the discovery of human disease genes has historically been an arduous undertaking. Extensive and exhaustive studies of genetic inheritance and pedigrees in generations of families led to the discovery of the color blindness gene on the Y chromosome in the early 1990's. As more biological tools became available, the pace of gene discovery increased. However, much of the biological laboratory practices were still rooted in intensively manual procedures. With the introduction of computing power in the mid-1980's, disproportionate amount of resources were being applied to hundreds of individual gene discovery efforts, such as Huntington's Disease and muscular dystrophy. It was with this realization that a large-scale effort at mapping the human genome was undertaken and in 1990, the Human Genome Project was deemed possible and launched officially by the National Institute of Health (Pollack 1,2). Presently, computers are being used to hold the vast databases of all the sequencing information for every gene of the human DNA strand. If computers were not available, the paper needed to contain all this information would stack higher than the Washington Monument, over 555 feet high. And this would only be for the data, not the analysis of that data. Imagine the nightmare of trying to find the correct gene pair, there are over 3.2 billion of them, in all that paper. But providing a database for the sequencing information of the human genome is only one way in which computers are helping in the mapping of the human genome. They also provide the computational power needed to speed the calculations for each gene as well as producing maps and the such for genetic information on each chromosome (Smith 14). In fact, Compaq Computer Corporation built specific technology enabling completion of the Human Genome. In the future, computing power will become greater and greater allowing for faster calculations and analysis of sequencing data. Also, there will be new robotics, micro-fabrication technologies and laboratory information management systems that will have to be applied to the challenges of the Human Genome Project (Bishop, 137). Furthermore, cutting edge researchers believe the really important discoveries won't come from looking at linear strands of genes but from examining the interaction between dozens of genes at once. Scientists could in theory use "biochips," arrays of hundreds of bits of your DNA placed in a silicon wafer, to examine how how a drug would interact with your particular biochemistry (Moore, 56).
In 1963, when African-Americans were fighting for black and white equality, Martin Luther King, Jr. wrote “Letter from Birmingham Jail.” While confined in the Birmingham jail, King felt the need to respond to a letter published in the local newspaper. This letter criticized King’s intentions during his visit by saying they were untimely. As a way to defend his actions, King put together a number of arguments and beliefs that proved why taking direct action was necessary during a time of racial discrimination. Furthermore, to persuade his audience, King had to gain trust and share the emotional connection he had with his people. Today, “Letter to Birmingham Jail,” is known for its articulate and powerful use of ethos, pathos, and logos.
In the touching, influential letter, Letter from Birmingham Jail, Martin Luther King Jr. responds to the white, Alabama clergymen who condemned his movement as “unwise and untimely” (1) and delineates his motives for traveling to Birmingham, where whites consider him an “outsider” (1). Hoping to express his ambition of nonviolent protest in a sympathetic, deferential manner, he implores the white clergy to join the struggle for Civil Rights. Throughout the letter, he addresses and disputes against each negative argument by the whites, testifying his position unpretentiously, yet confidently. With aptitude, poise, and humility, King establishes his motives for coming to such an unwelcoming environment. In his heart-rending letter, King’s coherent logos, stimulating rhetorical questions, and accentuating parallel structure express to the white moderates who criticized his actions that nonviolent, direct protest is not only essential, but also inevitable to contain agitated hostility and to assume relative peace.
The Letter from Birmingham Jail was written in 1963 by Martin Luther King, Jr. During this period, the African Americans were involved in a battle for white and black equality. This is evident from the vocabulary used by King including “Negro” which was common during that period but not used commonly afterwards. Moreover, the letter’s context tells it argues that King wanted was African Americans to have freedom. The letter’s purpose is that King wants to persuade the clergymen what he together with his people were demonstrating since it was extremely necessary during that period. In achieving this, King utilizes persuasive and condemnatory tones so that the reader can consent with him. King Luther King, the author of Letter from Birmingham Jail, presents a valid argument through the use of ethos, pathos, and logos in the entire piece with the intention of explaining his actions and changing the audience’s opinions.
Inciting Incident: She ends up having to marry a tenant farmer and everyone thinks she could have done better.
“ Who controls the past controls the future. Who controls the present controls the past.” (32) That is one of the “Ingsoc” parties motto. Some of the characters in 1984, characters spent their days rewriting history to what the party wants, changing history. In today’s world, people depend on the internet, google or yahoo. But can those sources be trusted? Some websites aren’t what you think, like Wikipedia. Anyone can edit an article on Wikipedia, saying false information. So what is true? You will never know because nobody looks at encyclopedias anymore, they look at the internet because its faster. But is it more reliable?
In April 1963, the civil rights leader Dr. Martin Luther King, Jr., was jailed in Birmingham, Alabama, for leading anti-segregation protests. His" Letter from Birmingham Jail," is an accessible letter to eight white clergymen from Alabama. In it, King responds to a statement by these clergymen that communicate their belief that the struggle against segregation should be fought in the courts and not in the streets. Throughout the essay, he uses three main rhetorical devices: parallelism, allusions, and logos. These three devices help further his argument against the eight clergymen, that protesters have the noble obligation to stand up against unfair laws in a cordial manner.
Martin Luther King Jr. incorporates many rhetorical strategies in “Letter from Birmingham Jail”. He construes to the Clergymen why he is eager to adjust segregation laws. King relays his contradictions and arguments in a clear, considerate demeanor through the application of ethos, logos, and pathos.
In a Public Statement released by Eight Alabama Clergymen, there were a lot of shots taken at Martin Luther King Jr. and his work during the Civil Rights Movement. These claims aim towards his peaceful protests and work as an “outsider”, but each can be proven false with basic knowledge of the Civil Rights Movements. As result of these claims, Dr. King responded with his famous letter “A Letter from Birmingham Jail”.
The Letter from a Birmingham Jail was an open letter authored by Martin Luther King Jr. to defend his leadership and participation in the nonviolent civil rights demonstrations in Alabama. His letter directly addressed the eight fellow clergymen who presented a statement of denunciation for those actions; however, there was an ambiguous audience King intended to convey his message. As the civil, human and legal rights of African Americans in the United States were not completely established and in many cases ignored, Dr. King’s intend was to affect the hearts, minds and actions of many, both domestically and internationally, which included religious leaders, empathizers, lawmakers, and the whites and blacks who he considered part of the problem.
Martin Luther King Jr.’s “Letter from Birmingham Jail” was written while he was “confined in the Birmingham city jail.” His letter was a direct response to the eight Alabama clergymen who insisted that King’s use of nonviolent direct action was unlawful. The clergymen questioned his method of protests even though they had similar goals as King. In his letter, King illustrates the hardships and injustices that African Americans in the United States were enduring during the mid-twentieth century; doing so allows King to justify the nonviolent actions of his fellow protestors. King uses the classical appeals of ethos, pathos, and logos, along with his rhetorical situation, to support his claims about the racial discrimination and segregation in the United States.
In “Letter from Birmingham Jail” Martin Luther King Jr, responds to various criticisms directed against him by the white Clergymen. King responds to the criticisms in a professional manner but with a twist. He uses a respectable tone since they are men of good will. The white Clergymen publish an open letter about the racial problems in Alabama. The letter was direct to the outsider of their community, which was King. King agrees with some of the main points that the Clergymen said, but he turns what they say around on them. He uses important people and symbols to make his point across. Two criticisms that King uses are “unwise and untimely” and “tension”. For example, the Clergymen show how the police are doing their job as good law enforcers.
Voelker, Roger B. ¡§Who¡¦s Afraid of the Human Genome?¡¨ Hastings Center Report, July/August 1989: 19-21.
The debate over the importance of a Human Genome Project can be cleared up by looking at what the human genome actually is, and why knowing its DNA sequence can be beneficial to the scientific and the human community. The human genome is made up of about three billion base pairs, which contain about 100,000 genes. The 100,000 genes in the 46 human chromosomes only account for a small total of the DNA in our genome. Approximately 10 percent of our DNA make up these genes in our genome, these genes are what is actually encoded for and used by our body to make vital proteins needed for everyday life. The remaining 90 percent of our three billion base pairs are repeated sequences between genes that do not encode for any particular product. These repeated sequences account for the reason why 99 percent of any humans DNA is identical to another human's (1). With this knowledge many people believe it is not worth the time or money to sequence the entire human genome when only a small percent is used to encode for proteins. However, by sequencing the whole genome researchers will no longer have to do a needle in the haystack type of search for small genes, like the one found on chromosome four that is responsible for Huntington's disease (4). Also, knowing the complete human DNA sequence will allow scientists to determine the role and importance of the repeated DNA, non-protein encoding, sequences in our body.
Human Genome Project A genome is defined as the complete collection of an organisms genetic material. The human genome is composed of about 50,000 to 100,000 genes located on 23 pairs of chromosomes in a human cell. It is said that a single human chromosome may contain more than 250 million DNA base pairs, and it is estimated that the entire human genome consists of about 3 billion base pairs. The DNA is gathered through blood samples taken from many different people. Though each person has a unique set of DNA the difference in a given pair of samples is less than 1 percent making the differences pale in comparison to the similarities. The Human Genome Project is an international collaboration of scientists who’s goal is to gain a basic understanding of the genetic blueprint of a human being. This information is found in each cell of the body, encoded in the DNA. The intent of this project is to identify all genes in the nucleus of a human cell, to map where those genes are on the chromosomes of the nucleus, and to determine the seqeuncing or the order of these chemical subunits of the DNA. The idea to undertake such a project was came about through a series of scientific conferences held between 1985 and 1987. The actual project ,however, did not begin until 1990 with the expansion of funding from the NIH and DOE. There are many nations involved with this project as part of an informal pact including France, Germany, Japan, the United Kingdom, and many other european nations.
and tie in with false negative errors (Merkow, 2000). The intruder could then violate the system's operational security constraints (Merkow, 2000). This may be discovered by a human operator examining the logs from the intrusion detector, but it would also appear that system still seems to be working correctly (Merkow, 2000).