Bovine Spongiform Encephalopathy or Mad Cow Disease (BSE), degenerative brain disorder of cattle. Symptoms in cows include loss of coordination and a typical staggering gait. Affected animals also show signs of senility, for example, lack of interest in their surroundings, the abandonment of routine habits, disinterest in feed and water, or unpredictable behavior. Affected cattle show symptoms when they are three to ten years old.
First identified in Britain in November 1986, over 170,000 cases have since been recorded there. Sporadic incidences have been confirmed in other European countries, with Switzerland (over 260 cases) and Ireland (over 260 cases) identifying the largest number. It has also been recognized in Canada, where cases are confined to dairy cows imported from Britain. BSE has not been officially confirmed in the United States or any other major milk-producing country.
Autopsies of affected cattle reveal holes in the brain tissue that give it a spongy, or spongiform, texture. Similar spongiform diseases have been recognized in humans (for example, Creutzfeldt-Jakob disease or CJD) for over a century and in sheep (scrapie) for over 200 years. The cause of BSE is unproven, although there is strong evidence that prions, which may be infective proteins, are the agent. Other hypotheses suggest that prions work with an as yet undetected virus to cause the infection.
Recycled animal tissue, which had been routinely fed to British dairy cows as a protein supplement, was identified as the source of the infection. The European Commission's Scientific Veterinary Committee and the world control body, the Fédération Internationale des Epizooties (FNE) believes that BSE was originally spread from sheep's brains infected with scrapie and that its spread was accidentally accelerated by the ingestion of brain tissue taken from cows that had become infected with BSE.
Following through with this fodder transmission theory, the British government introduced compulsory destruction of suspect animals and their carcasses beginning in 1988. The feeding of animal tissue to cows was banned in Britain in July 1988 and since mid-1992, monitors working for the United Kingdom Ministry of Agriculture have recorded a persistent decline in the number of confirmed cases. It is estimated that the program will eradicate BSE in Britain by the end of 1999.
Since the initial report of the disease, there has been fear and speculation that it might be transferable to humans through milk or beef products. The appearance of CJD in several dairy farmers in Britain in the early 1990s heightened the alarm.
Bovine spongiform encephalopathy (BSE), more commonly known as mad cow disease, is an unusual disease in regards to the fact that it is not caused by bacteria, viruses, fungi, or any other organism. Instead the disease is caused by prions, infectious agents simply composed of protein. Prions lack nucleic acid and are composed of an abnormal isoform of a normal cellular protein. What this means is that the prions and the cellular proteins have the same arrangements of the amino acids; however, the prion is folded differently from the cellular protein. "They are much like the toy "Transformers" that intrigued little kids in the 1980s. A sphynx could become a robot; a bug could become a warrior. Nothing was added; nothing subtracted."(Ruth Levy Guyer, Ph.D., 1) The tightly wound alpha helixes (figure 2) of the normal cellular proteins are unfolded and turn into beta sheets (figure 1).
Mad Cow Disease, scientifically referred to as (BSE) Bovine Spongiform Encephalopathy, is a disease that affects those humans who eat the meat from infected cows. Mad Cow Disease is one of several fatal brain diseases called (TSE) Transmissible Spongiform Encephalopathy. (USDA) There was evidence of a new illness resembling the sheep disease scrapie. It was technically named BSE but quickly acquired the mad cow tag because of the way infected cattle behave. (CNN) In 1997, there was an award given to Stanley Prusiner, for concluding that a distorted protein called a prion was responsible for Mad Cow Disease, noted the long incubation period made it difficult to distinguish (Bryant). Another name for Mad Cow Disease is the new variant Cruetzfeldt-Jakob Disease (vCJD), similar to the Creutzfeldt-Jakob Disease, which is a deadly brain illness that strikes about one per million per year (USDA) due to genetic or unknown causes while the vCJD is contracted from eating infected cows (USDA). Both CJD and vCJD are so similarly named because of the similar effects from the illness.
Mad cow disease is caused by prions, "weird mutant proteins that are found in brain and spinal tissue"1. Another name for mad cow disease is called bovine spongiform encephalopathy (BSE) and the definition is "a progressive neurological disorder of cattle that results from infection by an unusual transmissible agent called a prion"2. It started from what is called a prion protein then it turned into a pathogenic, and then it starts to damaged the brain of a cattle. There's another name for this disease and it's called Creutzfeldt-Jakob Disease "a form of progressive dementia characterized by loss of nerve cells and degeneration of nerve cell membranes leading to the production of small holes in the brain. It is rare, degenerative, and invariably fatal"3. This disease happen in human causing lapses in the memory, mood swings similar to depression, lack of interest and social withdrawal3. It is said that this disease has no tr...
PrP can occur in two forms- a normal cellular prion protein known as PrPc and a pathogenic misfolded conformer known as PrPsc. The abnormal PrPsc differs from the normal prion protein PrPc in both secondary and tertiary structure. PrPsc is principally rich in Beta sheet contents but PrPc is principally rich in alpha helical contents. Due to this difference of between the isoforms, prions are extremely resistant to certain decontamination systems. The Two tables below outline both human and animal diseases (2).
Normally, cows in Northern Europe in places such as Denmark live normal lives simply grazing on grass, and existing. However, there have been recent changes that have disrupted this normal activity. Generally the bluetongue virus (spread by Culicoides imicola, a biting midge) has been confined to Southern Europe and other places around the Mediterranean. But with the increase in temperature throughout the area, the midge has been allowed to migrate northward. This new pest is a nuisance and causes lots of difficulties to farmers in the area. When a cow contracts this disease, they usually also receive oral ulcers, salivation, stiffness, fever and eventually the inevitable- death (Merck Veterinary Manual NP). Because of the increase in temperature, midges have spread around the globe infecting livestock and creating terrible trouble for many farmers.
In cows with mad-cow disease, the area that is most targeted is the brain. The prions enter the brain and start deteriorating the brain. This is also why the disease is referred to scientifically as spongiform, because it causes the brain to look like a sponge with holes and empty caverns throughout the brain of the infected animal.
As any romantic will assert, love is by far the most powerful force known to human hearts and minds. This sentiment is espoused throughout history, almost to the point of cliché. Everyone has heard the optimistic statement, “love conquers all,” and The Beatles are certain, however idyllic it may be, that “all you need is love.” Humanity is convinced that love is unique within human emotion, unequalled in its power to both lift the spirit up in throws of ecstasy, and cast it down in utter despair.
Man goes through life, waking each day and participating in his own existence without truly existing. He is always in search of a greater meaning, and in the process fails to find one as he is on a constant search for something that cannot be grasped by the normality that is the human psyche. A similar example can be found in the capitalistic work force of modern day. Man works the majority of his life, always training and aiming for more, only to retire and live on a portion of what he was making. During his time working he lost out on his family, his sleep, often times his own enjoyment, for an ideal that often times is never achieved. This is a trivial situation, yet it is painted in a rather angelic light in our society. Why is it, then, that Sartre can be dismissed as trivial when trivialities exist in nearly every day to day life? Quite likely, this is because Existentialism is an “on-paper theory” so to speak, and in theory is looks quite differently than in reality. Man, as in this case, does not realise that he often follows the rules which he opposes. In addition, much of today’s society exists under a form of organized religion, a society with which Existentialism exists in
He basically calls the people of Argos fools for following Zeus and repenting their sins. Here he is removing the people of free will, making them blindly follow this religion. I do think free will is often restricted, but by the person themselves, because they feel like they need to conform and follow this power. Sartre, through Orestes, makes it seem like you can only be free when you are free from power over you, therefore free from religion. I think this is a skewed view of life. Sartre generalizes followers of religion, specifically Catholicism, so much that they all seem like mindless clones. I am not religious, but I think people who follow religion don’t give it all the power. Rather than letting it have a hold over them, they work with it to make their decisions. Here is where I think Sartre fails. He is hypocritical. Sartre makes it seem like searching for answers or validation through religion is foolish, so instead, he gives us the answers he thinks are correct, he gives himself the power over the reader. He essentially makes himself into a god and existentialism into a religion, completely counteracting his previous points. Sartre is telling the reader that they are stupid, and existentialism is the right way, but since according to existentialism there is no right way, it all just becomes a never-ending, pointless
Throughout the tragedy of Romeo and Juliet, by William Shakespeare, various types of love are portrayed. According to some of the students of Shakespeare, Shakespeare himself had accumulated wisdom beyond his years in matters pertaining to love (Bloom 89). Undoubtedly, he draws upon this wealth of experience in allowing the audience to see various types of love personified. Shakespeare argues that there are several different types of love, the interchangeable love, the painful love and the love based on appearances, but only true love is worth having.
The Symposium, The Aeneid, and Confessions help demonstrate how the nature of love can be found in several places, whether it is in the mind, the body or the soul. These texts also provide with eye-opening views of love as they adjust our understanding of what love really is. By giving us reformed spectrum of love, one is able to engage in introspective thinking and determine if the things we love are truly worthy of our sentiment.
Sartre is one of the constructors of the philosophy of existence that is existentialism. Humans must first be born and exist before they are able to define their essence. He states that there is no universal statement about what humans are. But, there is one overall statement about the circumstances that make us human, which is that we are free. He believes that when we have to make decisions nothing is forcing us to do what we are doing. Which leads to the idea that humans have to take full responsibility for our actions, beliefs and emotions. By being aware that we are free, the responsibility of this can cause “anguish” according to Sartre. One of the most painful thoughts can be that we alone are totally responsible for what happens to us. To avoid the pain of some of the bad decisions we make people can act as if they had no choice and may pretend that they are not free which would make them not responsible. When you act like you were not free and are not responsible is known as having bad faith. That is humans try to convince themselves that outside forces, forces that are beyond control or our conscious mental state helped determine the decisions we made.
Upon reading Erich Fromm’s The Art of Loving, I gained a better understanding of what love really is. Fromm’s book puts love into perspective. He begins with several facts with regards to the attitude in which people treat love. They are the problems of how to be loved, the object to love as well as the confusion between the initial experience of falling in love and the permanent state of being in love, which had a great impact on me, as far as thinking about what love is.
Cows are naturally very gentle and calm creatures. These smart and sweet natured animals have been known to go to great lengths to escape slaughterhouses. More than forty-one million of these sensitive animals suffer and die a painful death each year in the United States. When cows are still very young they are burned with hot irons, there testicles are torn or cut off, all without painkillers. Most beef cattle are born in one state, live in another, and are slaughtered in another. The cows who survive the gruesome transportation process are shot in the head with a bolt gun, hung upside down by there legs, and taken onto the killing floor where there throats
“Love is the state in which man sees things most decidedly as they are not. The power of illusion is at its peak here, as is the power to sweeten and transfigure. In love man endures more, man bears everything. A religion had to be invented in which one could love: what is worst in life is thus overcome – it is not even seen any more.”