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Potential impacts of genetic engineering
Potential impacts of genetic engineering
Potential impacts of genetic engineering
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The film I Am Legend depicts the introduction and the aftermath of a genetically modified strain of measles, given to cancer-ridden individuals, in hopes of a cure. Although, it takes a turn for the worse when only 10% of the world’s population remains alive after three years and a lone virologist is left to cure this disease. This paper discusses the shortcomings, as well as plausible facts surrounding the virological processes behind the film. While there is a strong actuality of the cure for cancer being derived from a genetically modified strain of the measles virus, the other virological components behind the film I Am Legend are not factual in their entirety, because they do not take into consideration the actual process of acquiring …show more content…
In general, there is a high mutation rate among RNA viruses, mostly due to the absence of a proofreader, as well as the RNA polymerase errors (2). The researchers above discovered the measles virus to have a significantly high, average mutation rate of 9x10 -5 per base per replication, with regards to the average mutation rate of all RNA viruses, between 10-3 and 10-6 per base per replication. This high error rate among the RNA viruses can lead to the ability of the virus to go un-detected by the immune system in an individual, which in turn can increase the pathogenicity of the virus (2), which can be seen in the …show more content…
The two patients used in the Russell et al. study, were seronegative for measles exposure. The World Health Organization (WHO) has performed global analyses on the frequency of measles virus immunizations, and has found that approximately 84% of the population is vaccinated against this virus (4). Therefore, it can be assumed that a significant number, if not all of the patients administered this cancer-curing immunization in the film would have been previously vaccinated, rendering the oncolytic virotherapy
This summer we had an opportunity to dive into the world of bioweapons, through Richard Preston’s novel The Demon in the Freezer. His book explored the colorful world of smallpox and its use as a biological weapon. Earlier this week we were graced with this authors present for an ACES event. He discussed some of the found topics in his book such as animal testing, what small pox is, and even its eradication. One of the great things we had the chance of vocalizing were our many opinions on the gloom associated with this intriguing disease.
The authors used a historical timeline to introduce a need. Stressing the number of lives lost allows the authors show the importance of vaccines. The repeated emphasis on those lives being the lives of children played on the emotions of readers. Once the need is established Lee and Carson-Dewitt clarify the use of “a dead or mild form of a virus” to create a vaccine (Lee, Carson-Dewitt, 2016, p.2). The distinction of the types of
Vaccine safety is one of the most controversial topics in today’s public discourse. Everyone has heard of them, but few know why they are so encouraged. A vaccine contains a weak or dead version of a microbe. This creates a small scale invasion of the immune system, which activates cells to destroy the microbe. Once these cells have been made they are always there to provide protection. This protection is immunity, for those cells are then able to recognize any live version of the same microbe and attack it immediately. This can save lives but also be dangerous, vaccines carry many other components which can cause side effects. These could be simple adverse effects such as a small cold or, in the rare case,
The perspective the author gives to this book is a unique. Smallpox according to most histories does not play the role of a major character, but a minor part. In my opinion smallpox was a major factor during the Revolutionary War, and Feen focuses on several key areas which allows us to see just how bad this epidemic was and the grip it had not only on the soldiers, but the colonist as well.
The Measles starts with a fever, runny nose, cough, red eyes, and sore throat. It is then followed by a rash that spreads over the body, starting first on the face along the hairline. The infectious period of measles is 4 days before rash onset through 4 days after rash onset. The measles are a highly contagious virus that lives in the nose and throat mucus and spreads through the air through coughing and sneezing. (WHO, 2016). The measles virus can remain airborne for up to an hour after the infected person has left the area. The measles are so contagious that if one person has it, 90% of the unvaccinated people close to them will become infected. Rarely can the virus be deadly. The incubation period for
Mumps is a paramyxovirus that is closely related to the parainfluenza virus. Its symptoms were first described in the 5th century BC, and it was a very common childhood affliction until the last several decades. It was identified as a virus in 1934, and an effective vaccine was developed in 1967. Mumps is acquired by aerosol, necessitating close human interaction for spread. Human beings are the only known reservoir for mumps virus, and there is only one serotype.
...Although these were initially set to prevent infectious diseases it has been found that there is also prevention of autoimmune diseases, birth control and also cancer therapy. While vaccines provide a proficient means of preventing diseases and improving public health it doesn’t mean all are essential to a healthy life, some do more damage if a sufficient immune system is not present. How the vaccine is formulated and distributed is important to study and follow up on to be certain it is in the best interest of your body to receive the vaccine. Vaccinations will remain present, but it is our choice as individuals to know what they are composed of and how they are administered. Immunizations should be valued and taken seriously, this advancement in technology came at a high speed, which means flaws, and errors will exist, whether we notice them now or in the future.
For approximately three-thousand years, smallpox has ravaged and plagued the four corners of the globe. In fact, in the 17 th and 18 th centuries, it was claimed to be the most infectious disease in the West, with an astounding 90% mortality rate in America. It wasn't until 1796, with English surgeon Edward Jenner's smallpox vaccination, that the world saw relief from this devastating virus. However, even with this inoculation in use, the world continued to witness death from both the virus and the vaccine. In the year 1966, it was estimated that 10-15 million infected citizens world wide had passed away from smallpox that year alone ( “History” 12). As a result of these devastating numbers, in the following year, 1967, the World Health Organization (W.H.O.) created a program to eradicate the smallpox virus. Ten years later, in 1977, the estimated 10-15 million cases had dwindled down to one; a man in Somalia. Three years later, W.H.O. officially announced that smallpox had been eradicated, leaving the only remaining virus cultures stored and guarded in laboratories in Russia and the United States. Inoculations ceased, smallpox epidemics were non-existent, and the virus was no longer a concern. In order to ensure complete eradication of this deadly virus, the W.H.O. insisted that the remaining smallpox cultures be destroyed by 1999 ( “Smallpox Eradication” 2). However, despite the W.H.O.'s recommendation, the remaining cultures continue to be contained and protected to this day, five years after the suggested date of elimination.
In the 1950s, a majority of the people were concerned about the things circulating in their everyday lives that they could not see: germs. These fragments of bacteria were intimidating and seemed impossible to stop. “The two most feared germs are bacteria (one-celled microorganisms) and viruses (ultramicroscopic or submicroscopic agents). During the decade, researchers made great strides in the understanding and control of these tiny enemies. In 1947, sixty viruses were thought to contribute to human disease; by 1959, seventy-six new ones had been identified.” (encyclopedia 3). As time went on, no one knew how to describe the fear they had acquired from the virus, as well as the sickness they had experienced.
Vaccinations have significantly reduced the disease rate throughout the world. Usually, vaccines prove to be between 90 and 99 percent effective. This reduces disease and mortality rate by thousands every year (Jolley and Douglas 1). On average, vaccines save the lives of 33,000 innocent children every year (“Vaccines” 1). In addition, if a vaccinated child did contract the vaccine’s targeted illness, that child would, in general, have more mild symptoms than an unvaccinated child that contracts the same illness. These vaccinated children will have less serious complications if they do contract the disease; they will be much more treatable, and have a lower risk of death (Jolley and Douglas 2). The risks of not vaccinating greatly outweigh the small risks of vaccination. Diseases like measles and mumps can cause permanent disability. While there i...
Vaccinations are not as dangerous as people make them seem, but not getting vaccinated is. Frances Childs states that “as the number of children who have not been immunized increases, so, too, does the likelihood of measles spreading”. Immunizations work by injecting a small amount of the virus into the patient (both children and adults). The patient’s immune system then builds up antibodies to fight against the virus, thus building immunity against the disease much more effectively. Vaccinations have a 90-100 percent chance of success.
The 20th-century was a time period where Western Medicine underwent many triumphs and tragedies. Along with the development of life saving technologies and vaccines, came violation of people’s trust and abuse of professional power. One event that stands out significantly occurred in the mid 20th-century, not only changed Western medicine forever, but affected many other parts of the world, as well. An immortal line of cells was discovered. This meant that these specific cells would never die, could be studied in great detail, and used in various experiments that couldn’t be done with living human beings. These cells were called HeLa and are still referred to as such today, and have been involved in the development of the polio vaccine and other
Nobody knows what measles is (Parker).” In a study published in the Proceedings of the National Academy of Sciences, a group of 315 people were surveyed on their attitudes toward vaccines. After the survey, the subjects were divided into three groups. One group was given the most recent research showing no link between vaccines and autism; another was read a paragraph written in a mother’s voice, describing her child’s contraction of measles, shown three pictures of children with measles, mumps, rubella, and read warnings about the dangers of not vaccinating. The third group, as a control, was given an unrelated science article to read.
For innumerable centuries, unrelenting strains of disease have ravaged society. From the polio epidemic in the twentieth century to the measles cases in the latter half of the century, such an adverse component of nature has taken the lives of many. In 1796, Edward Jenner discovered that exposure to cowpox could foster immunity against smallpox; through injecting the cowpox into another person’s arm, he founded the revolutionary concept known as a vaccination. While many attribute the eradication of various diseases to vaccines, many United States citizens are progressively beginning to oppose them. Many deludedly thought that measles had been completely terminated throughout the United States.