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Essay about Rosalind Franklin
James Watson and his contribution to DNA
James Watson and his contribution to DNA
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Recommended: Essay about Rosalind Franklin
Franklin, Rosalind (1920 - 1958)
Franklin was a Londoner by birth. After graduating from Cambridge
University, she joined the staff of the British Coal Utilisation
Research Association in 1942, moving in 1947 to the Laboratoire
Centrale des Services Chimique de L'Etat in Paris. She returned to
England in 1950 and held research appointments at London University,
initially at King's College from 1951 to 1953 and thereafter at
Birkbeck College until her untimely death from cancer at the age of
37.
Franklin played a major part in the discovery of the structure of DNA
by James Watson and Francis Crick. With the unflattering and distorted
picture presented by Watson in his The Double Helix (1968) her role in
this has become somewhat controversial. At King's, she had been
recruited to work on biological molecules and her director, John
Randall, had specifically instructed her to work on the structure of
DNA. When she later learned that Maurice Wilkins, a colleague at
King's, also intended to work on DNA, she felt unable to cooperate
with him. Nor did she feel much respect for the early attempts of
Watson and Crick in Cambridge to establish the structure.
The causes of friction were various ranging from simple personality
clashes to, it has been said, male hostility to the invasion of their
private club by a woman. Despite this unsatisfactory background
Franklin did obtain results without which the structure established by
Watson and Crick would have been at the least delayed. The most
important of these was her x-ray photograph of hydrated DNA, the
so-called B form, the most revealing such photograph then available.
Watson fir...
... middle of paper ...
...anklin's showing an image of the now famous Photo 51.
Franklin, went on to study the tobacco mosaic virus, and continued her
work in absolute dedication, despite having been diagnosed with cancer
in 1956 (probably due to the chemicals she was using). She died two
years later, 37 years old, never knowing how much her work had played
a role in Watson and Crick's discovery. In 1963 they received the
Nobel prize for their discovery, along with Wilkins, Franklin's
collaborator. In 1968 Watson's popular book, The Double Helix,
recounted the events leading to their ultimate discovery, making clear
for the first time how critical Franklin's experimental work had been.
Franklin's social isolation prompted by the contempt male scientists
showed toward her as a woman-scientist, is one of the tragedies in the
history of science.
In this case, the reward for winning the “competition” is so significant that better opportunities are overlooked and some are left without the aid they need. When Watson and Crick ask Rosalind Franklin’s opinion on their model of DNA, the result they are looking for is far from what they had hoped: “Rosy did not give a hoot about the priority of...
John Hope Franklin’s childhood had a huge impact on his life and scholarship. His parents were a primary influence in his education and much of the subjects he was passi...
Benjamin Franklin was a remarkably talented man. He started his life as a printers apprentice, but went much farther then there. He developed things that were far more advanced than the time. Benjamin Franklin's stove for example, for cold winter nights, and bifocal lenses for reading. Franklin tracked storms to help understand the horrible weather endured by the colonies. But gis study of electricity made him mist famous and he was known world wide as the founder of the lightning rod. Not only was Benjamin Franklin helpful in developing ideas for better living, he was also a strong force in developing the new nation of America. Benjamin Franklins political views showed him to be a man who loved freedom and independence. His views towards England gradually changed from like to dislike until he finally
...or instance, hepatitis C virus), biological molecules (such as cyclic adenosine monophosphate), and Human Immunodeficiency (HIV) virus (Bauman et. al. 2011). Rosalyn had went farther in the world of science than anyone including her self thought was possible (Bauman et. al. 2011). Rosayln and Berson changed history, altered the way science was perceived and their time, and how today we see and research science.
The following is a review of the book, The Double Helix, by James D. Watson that was published in 1968. Here the Norton Critical Edition will be used for page numbering and insights for this review, which was edited by Gunter S. Stent and published in 1980. The Double Helix is a personal recollection of the period of time when the structure of DNA was discovered. James D. Watson (Watson) along with Francis Crick (Crick) were the two scientists who published a paper in 1953 which purposed a structure for DNA. For the most part their structure has stood the test of time, and since that time period many people have wanted to know details of how they discovered DNA’s structure (pp. 3). Therefore Watson’s purpose in writing the book was to describe his personal view of the events that lead to discovery of DNA’s three-dimensional structure, when they happened in 1952-53. He is well qualified to give an account of these things, for he was there in the middle of everything; he was one of the main players. In order to describe the events, apart from his sharp memory, Watson used letters he wrote to his family to help him remember dates and details, as well as suggestions from his associates who reviewed his manuscript. In the following paragraphs I will summarize the text, and follow that with my own review of
The Autobiography of Benjamin Franklin is a representation of the new prospect of upward mobility in colonial America during the 18th century and the development of the Age of Reason, which assisted in the conception of the idea of the “American Dream”; a dream that includes fundamentally social ideals such as democracy, equality, and material prosperity. Furthermore, Franklin’s autobiography exemplifies a significant shift in focus from religion to enlightenment and reason. Additionally, there were forces specific to Benjamin Franklin's Philadelphia, that played an important role in his perspectives and the changes that occurred within colonial America during the 18th century.
In The Autobiography, Benjamin Franklin recounts the many paramount experiences throughout his life that shaped him into great American figure he was known to be. On the opening page, Franklin reveals the book’s epistolary format by writing, “Dear Son,” going on to admit that he’s made some mistakes in the past and to recollect that past is a way to relive it. By divulging his desire to “change some sinister Accidents & Events” (Franklin 3) the author indicates how important it is for his son to observe as he amends his mistakes. Pride, virtue and vanity play a pivotal role in Benjamin Franklin’s life and the way he portrays himself to others. Instances occur where the author is shown gloating about his great accomplishments and he puts emphasis on his need to live a virtuous and morally perfect life. Throughout his story, Benjamin Franklin tells his son of his many virtuous acts and momentous achievements, motivating the question as to whether he seeks his own approval more so than the approval of his peers.
	X-ray crystallography helped determined the three dimensional structure of DNA when Franklin returned to England. She became the first person to find the molecule¡¯s sugar-phosphate backbone while working with a team of scientists at King¡¯s College in London. Unfortunately, leadership misunderstandings and personality conflicts depreciated Franklin¡¯s effectivness in the laboratory. Maurice Wilkins, the laboratory¡¯s second in command, returned from a vacation expecting Franklin to work under him. Franklin came to the laboratory with the understanding that she would be researching alone. While Franklin was direct and decisive, Wilkins tended to be alluding and passive-aggressive. As Franklin made further advances in DNA research, Wilkins secretly shared her findings with the famous duo of Watson and Crick, who were then working at Cambridge. Franklin¡¯s discoveries fueled their research machine, allowing them to advance beyond others in the field. They would eventually publish on DNA structure in 1953. Due to discriminatory procedures at King¡¯s College, Franklin eventually left to become the lead researcher at London¡¯s Birbeck College--upon agreeing not to work on DNA. She furthered her studies in coal and made significant advances in virology. Franklin died in 1958 of ovarian cancer. She lived 37 monumentally significant years.
In whatever Franklin did, she wholeheartedly pursued it with her heart and gave her full potential. Despite her thorough and diligent ways of conducting her work and research, it did not mean she was respected by everyone. In fact, during her time at King’s College London, Franklin did not get along with her colleague, Maurice Wilkins. Without Franklin’s permission or knowledge, Wilkins disclosed Franklin's photograph 51 to competing scientist James Watson, who was also working on DNA. Eventually, James Watson and his partner Francis Crick used Franklin’s photograph 51 to back up their theory of the DNA model structure. It was due to the conflict between Franklin and Wilkins that played a key factor in Franklin leaving King’s College and relocating to Birkbeck College. Franklin’s life and career was cut short when Franklin discovered she had ovarian cancer and passed away on April 16, 1958, at the age of only 37. Nevertheless, Franklin still managed to contribute immensely to physics and the world in many
Francis Crick: He does the same research with Watson and they are both teammates. He is also eager to know what is in DNA and the relationship of it with the double-helix, but at the same time is disorganised, and expected Watson to do a majority of work.
She further improved her skills and eventually came to discover through the x-rays that there were two different forms of DNA, the A form and the B form. Franklin chose to focus more on the A form when she presented her findings to an audience, which included James Watson, who was sent by Francis Crick, to spy on her findings. Watson and Crick were rival scientists trying to win the race to find the structure of DNA - before the unknowing Franklin did. When Watson reported back with her information on the A form of DNA, the two were quick to build a model. However, after being invited to the showcase, Franklin came to examine it and nearly immediately disproved the model, showing the reality of the situation - Watson and Crick’s model was a failure. The head of the lab that the two worked at banned them from working on models again, leaving them humiliated. Then, in May of 1952, Franklin took the clearest photo of the B form of DNA she ever had taken and labeled it as “Photo 51”. She stores it away for later examination, but it somehow ends up in the hands of Wilkins, who shows it to Watson. Soon, Watson and Crick, using the photograph and Franklin’s other research, are able to figure out the double helix structure, dimensions, and arrangement of components of DNA. They publish their findings in a series of
So, while this woman has never been in the limelight, she pioneered molecular genetics as it is today. Without her stubborn need for the facts, the human genome would still be an enigma to us today. She is truly a role model for all women today.
Benjamin Franklin has been without a doubt one of the most relevant individuals in US history. His autobiography gives us a brief but detailed summary of what his life was like and how society worked in the eighteen century. This autobiography gives us many details of how the colonies where and offers and an overall image of the development of British North America which later turned into the United States. Due to the fact that this book was originally written for Franklin's son, the book concentrates in personal information and has very little information about other topics. However, there are some topics that can be extracted from his writings; one of them is gender. Even though, Franklin never talks openly about gender, we can observe how in his writing these roles are clearly assigned. In this paper, we will analyze how Benjamin's Franklin autobiography showcases the importance of gender in the early eighteenth century. Gender can be analyzed in Franklins book by looking at different topics. This given to men and women by society can be seen in the workspace, in the education of each individual, and in the family and family structure.
"The discovery of the structure by Crick and Watson, with all its biological implications, has been one of the major scientific events of this century." (Bragg, The Double Helix, p1) In the story of The Double Helix, James Watson tells of the road that led to the discovery of life's basic building block-DNA. This autobiography gives insight into science and the workings within a professional research laboratory that few members of society will ever be able to experience. It also gives the reader an idea of the reality of life for one scientist and how he struggled with the problem of DNA. However, the author's style is marked by his lack of objectivity and inclusion of many biased opinions and personal prejudices.
She began her studies at St. Paul’s Girls’ School with her family discouraging her from aiming to get into the scientific field, mainly because it was difficult for a woman of that time. She gained a degree in physics with a specialty in chemistry from Newnham College before receiving admission to Cambridge University. Unfortunately, her father was opposed to the education of women and refused to pay for Rosalind’s tuition. Luckily, an aunt stepped up and offered to pay for her education, feeling that Rosalind should attend school. Her own mother was also in favor of Rosalind receiving an education and soon her father gave in.