2.1.1.a Flexor Tendon and Rotator Cuff
The ability to flex the finger consists of a serial of flexor muscles in the forearm and their tendons are inserted to the bones of finger. The injury of flexor tendon might cause the loss of bending of the fingers or thumb. The flexor digitorum profundus tendon (FDP) attaching to the distal phalanx and the flexor digitorum superficialis tendon banding to middle phalanx well demonstrated the specific type of tendon-to-bone insertion site characterized by the four-zone enthesis.[1] The retinacula (sheath) structures serve as strong fibrous bands wrap around the flexor tendons in order to keep the flexor tendons in place while flexion.
Injuries to flexor tendon remain the most difficult problem among
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No obvious boundaries are observed between the two distinct materials, tendon and bone. Type I collagen and tenocytes are highly aligned in tendon. In uncalcified fibrocartilage, where collagen type II is of great content, along with rich type III collagen and small amount of type X collagen, decorin, and aggrecan. Similarly, with a great amount of type II collagen, the mineralized cartilage presents significant amounts of collagen type X and scarce levels of aggrecan. Note that the collagen fibers are highly aligned in the direction of tensile force in tendon but less oriented in the insertion site (Figure 2).[4, 19] Additionally, the insertion site possesses a transitional decrease in tissue organization while an increase in mineral content.[4] The complex collagen and mineralization content in this region lead the repair and rehabilitation of tendon-to-bone insertion site more …show more content…
Plenty of experiments and tests have been performed in order to regenerate the four zone
The origin of the triceps brachii is also from the scapula like the biceps brachii. In a mink, the extensor digitorium originates on the lateral epicondyle of the humerus yet in humans it is present in the posterior forearm and is responsible for extending the phalanges, wrist, and elbow in both species. Anothier muscle with similar functions to the extensor digitorium is the flexor carpi ulnaris but instead it is soley responsible for flexin... ... middle of paper ... ...
... It is not completely clear how it is that a tendon becomes a ligament, although Dr. Akizuki thinks that range of motion exercises help the tendon learn that it is being used as a ligament now and that it needs to adopt. Surgeons don't go back in to biopsy the repaired elbow to see how the tissue has changed, but follow-up MRIs show that the new tissue is acting as a ligament should.
Tendinopathy is a generic description that encompasses many pathologies of clinical conditions arising from chronic overuse in and around the tendon such as ruptures/tendinitis, tendinosis and paratendinitis, which can only be classified post histopathological examination (Maffulli, Sharma, & Luscombe, 2004; Khan, Cook, Bonar, Harcourt, & Astrom, 1999). There has been a shift to replace the pathological term ‘tendinitis’ with ‘tendinosis’ as increasing research fails to detect the presence of prostaglandin mediated inflammatory cell infiltration within the pathological tendon (Khan, Cook, & Kannus, 2002; Khan et al. 1999). Achilles tendinosis pathology is now attributed to a failure of the cell matrix to adapt to repetitive trauma. With fiber disorientation, ...
The all too familiar "pop!" immediately followed by weakness, pain, and immobility; the classic signs of a shoulder injury. Many shoulder injuries affect the rotator cuff. "Each year approximately 200,000 American require surgery related to the repair of the rotator cuff" (Yamaguchi). This vast number of surgeries makes shoulder injuries a popular topic in the medical field. Physicians have been researching ways to improve patients' recovery and return their range of motion back to normal. One such improvement is the release of the long head of the biceps tendon.
The flexor tendons are not involved, although it may appear so in advanced contractions. Trauma may accelerate and in some cases even begin the process.
Not all attributes are obvious for every situation. The lion's share of instances of OI (conceivably 85-90 %) are created by a predominant change in a quality coding for sort I collagen (Types I, II, III, and IV in the accompanying rundown). Sorts VII and VIII are recently recognized structures that are acquired in a passive way. The qualities bringing about these two sorts have been recognized. Sorts V and VI don't have a sort 1 collagen change, however the qualities bringing about them have not yet been recognized. The general components of each referred to sort of OI are as per the
covers the area, causing people, animals, and structures to practically disintegrate. Even years afterwards people were still dying and having
Carpal Tunnel Syndrome Abstract The wrist is surrounded by a band of fibrous tissue, which normally functions as a support for the joint. The tight space between this fibrous band and the wrist bone is called the carpal tunnel (The Stay Well Company, 1999). The median nerve passes through the carpal tunnel to receive sensations from the thumb, index, and middle fingers of the hand.
Repair after a muscle is damaged happens through the division of certain cells who then fuse to existing, undamaged muscle fibers to correct the damage. Different muscle types take different amounts of time to heal and regenerate after it has been damaged. Smooth muscle cells can regenerate with the greatest capacity due to their ability to divide and create many more cells to help out. While cardiac muscle cells hardly regenerate at all due to the lack of specialized cells that aid in repair and regeneration. In skeletal muscle, satellite cells aid in helping restoration after injury. Along with muscles, tendons are very important structures within the human body, and they to can be damaged. However, tendon repair involves fibroblast cells cross-linking collagen fibers that aid in not only reinforcing structural support, but also mechanical support as well (“Understanding Tendon Injury,” 2005). While quite different from muscle repair, tendon repair involves the similarity of reestablishing d...
Theoretically if we have not done experiments on Bikini Atoll the Bikinians would be alive.
The solution to this problem is located in the lab. Researchers across the country are working day in and day out to come up with a solution to accelerate the healing of soft tissues. They have come up with many solutions, from vibration therapy, to personalized rehab plans, but none of these are yielding truly significant results. I believe the solution lies at the molecular level. I believe that we can observe the healing of these soft connective tissues and learn from it. Then we can design a method from the observations to accelerate the production of the fibrils and collagen that will go on to make up the soft connective tissue. I have begun to take the beginning steps in solving this problem through my mentorship with Dr. Weinhold. Our research goals go hand in hand, which has led us to beginning research on the release of an angiogenic growth factor through a gelatin that will coat sutures. In theory, this angiogenic growth factor, once released from the crosslinking with the gelatin will stimulate the development of blood vessels around the recently repaired collagenous tissue. This, in turn, will allow the tendon/ligament to have a better oxygen supply and allow for quicker
Tendons are surrounded by loose areolar connective tissue called paratenon. The main components of the paratenon are the type I collogen about 95% and about 5% of type II collagen of the dry tendon weight but smaller quantities of other collagens are also present, including types V, VI, XII and type II collagen (Robi et al. 2013).
Wang PhD, James, and Jianying Zhang PhD. "Platelet-Rich Plasma Releasate Promotes Differentiation of Tendon Stem Cells Into Active Tenocytes." The American Journal of Sports Medicine 88.12 (2010): 2477-486. Print.
how there are contrary belief that living forms are indeed growing in the Badlands country. This caused
...eral development and deposits in ways that is not high in environmental impact or harm.