Acromegaly is a pituitary gland disorder that is an unusual and rare disease that comes from the hypersecretion of growth hormone during adulthood. It is rare in that acromegaly occurs in about 5 cases per million per year (Lugo 2011). Acromegaly if often labeled as a prolonged metabolic condition that is characterized by steady enlargement or elongation of facial bones and extremities (Thibodeau, 2013). This paper will explain the disease and how it affects the body, how one who has the disease might act and how to diagnose the disorder, and how to treat the disorder and ways for prevention of acromegaly. Acromegaly causes a number of physical changes over time. Since growth hormone is accountable for organ, bone, and muscle growth, excess growth hormone leads to an abnormal growth of these tissues. Individuals with acromegaly may have swelling in the hands and feet and develop a severe facial appearance as the jawbone projects, the tongue enlarges, and the chest rounds (Reid, 2009). The heart grows larger, which damages its role, and other tissue growth tightens the nerv...
The historian Richard White states the Columbia River, located in the states of Washington and Oregon in the Northwest portion of the United States, as an Organic Machine made by arguments that the habitat established by the environment dictates the survival of mankind. It was previously assumed that mankind dictates the laws of its existence and that the environment is simply a small obstacle that can be overcome. Richard White proves former beliefs about the relationship between mankind and its environment or habitat untrue through the book The Organic Machine by showing the reader why the Columbia River is a perfect example of an organic machine, how organic machines affect lives and different civilizations, and how the alterations that mankind makes can effect the river as a whole.
Complex linkages are system of activities, business organization, resources, and information involved in transferring services and product from supplier of the product to customers. In complex linkage, the products and services from a single company interact in several ways. The complex linkage needed for a competitive business environment should focus on business management, connection with other countries, development of new markets, and technology.
The Complexity of Arnold-Chiari Malformation. To the medical doctor, Arnold-Chiari Malformation, which may have a genetic link, is characterized by a small or misshapen posterior fossa (the depression in the back of the skull), a reduction in cerebrospinal fluid pathways and a protrusion of the cerebellar tonsils through the bottom of the skull (foramen magnum) into the spinal canal resulting in a multitude of sensory-motor problems and even some autonomous malfunctions (1). These symptoms can come in a variety of forms, which often makes a clinical diagnosis difficult. To the patient, this disorder can present not only physical difficulties but also mental distress.
Kalus A.A., Chien A.J., Olerud J.E. (2012). Chapter 151. Diabetes Mellitus and Other Endocrine Diseases. In Goldsmith L.A., Katz S.I., Gilchrest B.A., Paller A.S., Leffell D.J., Wolff K (Eds), Fitzpatrick's Dermatology in General Medicine, 8e. Retrieved March 29, 2014 from http://accessmedicine.mhmedical.com/content.aspx?bookid=392&Sectionid=411388744
ACH, is an interesting disease, one that after many years of research still remains a partial mystery. The fact that a single nucleotide on one chromosome can so greatly affect an individual is astounding, especially coupled with the fact that this mutation is so homogenious in genotype and phenotype. With more skeletal dysplasias being connected to FGFR3, research has increased to fully determine and define the pathways involved with this gene. Determining the reason for such a high mutation frequency and the link to paternal age are also being looked into. Once there is more understanding of how this mutation affects the body, treatments and possibly cures can be found for these individuals.
Ivy was born with achondroplasia, the most common form of dwarfism. It is caused by the presence of two mutant alleles in the fibroblast growth factor receptor-3 (FGFR3). It is a substitution, to be precise, at nucleotide number 1138 in the DNA. This substitution on the DNA level results in a minute change on the protein level. This change in the protein impairs the function of the FGFR3 receptor. It is not currently known how this change produces the features of achondroplasia, but scientists are working on it.
Congenital Adrenal Hyperplasia (CAH) is an inherited condition that affects hormone production in the adrenal gland. The individual lacks enzymes to make cortisol, and hormones are instead are shifted away to make other hormones, specifically androgens. This results in the deficiency of cortisol and the abundance of testosterone.
Achondroplasia is a genetic disorder in which there is a growth hormone deficiency, or there is a genetic mutation in either the father’s sperm or mother’s egg. Mayo Clinic, March 20, 2014. Achondroplasia was the first discovered in ancient Egyptian records. People with achondroplasia are considered people with supernatural powers. Many people call dwarfs midgets, but to them, it is very disrespectful because midget literally means little person.
HGH (Human Growth Hormones), Steroids and other PED’s (Performance Enhancing Drugs) have been linked to the game of baseball now since the 1990’s. Some wonder if these such drugs in fact hurt the human body. Yes they do. The drugs these athletes are putting into their bodies are often foreign things. However HGH is a substance that is produced in the pituitary gland. The substance regulates somatic bodily and skeletal growth says Robert E. Murphy of the Huffington Post (Par. 4). Murphy also goes on to talk about how HGH is most often found in young children and adolescence but it continues to sustain adult tissues and organs. So by putting or replacing what the young adults are starting to lack will in fact will strengthen and athletically enhance the athlete or person that takes this HGH. In 2008 a Stanford University study reported growth-hormone injections increased muscle bulk and not strength, and in fact might be a cause of muscle fatigue and joint-pain. Murphy talks about how The Mayo Clinic website incorporates such ...
particularly if the treatment is started at a young age (Ross par. 15). The growth hormone treatment can eventually increase the girl’s final adult height by several inches.
Algernon is a super genius. He can complete difficult tests and also happens to be a mouse. Algernon’s character develops in three stages. His peak in intelligence after an experimental operation defines him in the beginning. Later, Algernon is frustrated when this new intelligence begins to wear off. His brain continues to regress to a level even lower than it was prior to the operation, ultimately ending in his death. These stages are not only important for the character development of Algernon but for Charlie’s too.
Generally, steroid therapy, a non-surgical treatment, is only used to treat hemangiomas because their location may cause complications that must be treated immediately. For instance, hemangiomas appears in areas such as the head, neck, cheek, eyes, and nose; these are all locations which may cause blindness, airway blockage, or cardiac failure. According to the Vascular Birthmark Foundation, “Hemangiomas can grow for up to 18 months and then begin a long slow regression...
Arthrogryposis is a disorder in which a child is born with joint contractures; this means some of their joints may be stuck in one position (curved or crooked). Children born with this disorder may have thin, weak, stiff, or missing muscles around these joints. The most common cause of arthrogryposis is fetal akinesia which is where the baby doesn’t move around a lot in the womb during development. Extra tissue can form in the joints making movement more difficult for the child to move. The reasons that fetal akinesia can take place may be because the womb was abnormally shaped so there wasn’t enough room for the baby to move around, amniotic fluid may have leaked out of the womb, or the baby’s parts did not form normally such as joints, bones, and muscles. They have also found that in approximately one third of the children who have this disorder have been determined to be a genetic cause.
The Computron, Inc. is facing problems regarding pricing the bid for Computron 1000X, future functioning of Frankfurt plant, impact on production due to current market breakdown.
There are many different types of dwarfism that researchers have confirmed today, but there still are many genes for dwarfism that remain unidentified.The most common of these known causes is achondroplasia, a bone growth disorder.The Little People Online website states that most dwarfs who suffer from achondroplasia are born to “average-size” parents, and that their birth rate is somewhere between onein26,000-40,000www.lpaonline.org).The main characteristics of this form of dwarfism are normal trunk size with short appendages, irregularly large heads wi...