The Structure of Adenosine Triphosphate, ATP

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ATP is universal form of free energy in all living organisms and is an energy coupling agent (Tymoczko et al. 2013. p. 250). When ATP is hydrolyzed to produce adenosine diphosphate (ADP) and orthophosphate (Pi), or to adenosine monophosphate (AMP) and Pi, free energy is liberated. This free energy can then be utilized for endergonic reactions that need an input of free energy in order to occur. The recycling of ATP/ADP is critical to for energy exchange in living organisms. ATP is critical in photosynthesis since it is used to produce carbohydrates from carbon dioxide (Tymoczko et al. 2013. p. 407). Thermodynamically unfavorable reactions can be also driven if they are coupled to ATP hydrolysis in a new reaction (Tymoczko et al. 2013. p. 250).

The structure of adenosine triphosphate (ATP) is composed of a ribose sugar molecule attached to the nucleotide base adenine on one side, and attached to three phosphate groups (in a triphosphate unit) on the other side of the ribose sugar (Adenosine Triphosphate-ATP). The ATP molecule contains two phosphoanhydride bonds which join the three phosphate groups together and a phosphoester bond that connects one of phosphate groups to the ribose molecule (Properties of ATP). The two phosphoanhydride bonds are formed by the loss of a water molecule (Tymoczko et al. 2013. p. 250). ATP is formed in chemotrophs through the oxidation of carbon fuels and in photosynthetic organisms when light energy is converted into chemical energy (Topic 4.2-The Structure and Role of ATP). ATP has a high phosphoryl transfer potential due to its structural differences compared to ADP and Pi. These structural differences include (1) electrostatic repulsion, (2) resonance stabilization, and (3) stabilization du...

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...ibulose 1,5-bisphosphate (Tymoczko et al. 2013. p. 412). 12 NADPH are also used in the reduction of the 12 molecules of 1,3-phosphoglycerate produced during the 6 rounds. Therefore, ATP has a critical role in the functioning of the Calvin cycle and photosynthesis since without it, plants would be unable to complete the Calvin cycle and synthesize the hexose carbohydrate sugars (Tymoczko et al. 2013. p. 412)

Works Cited
May, P. Adenosine Triphosphate-ATP. Bristol University. Retrieved from http://www.chm.bris.ac.uk/motm/atp/atp1.htm

Properties of ATP. UC Davis. Retrieved from http://biowiki.ucdavis.edu/Biochemistry/Oxidation_and_Phosphorylation/ATP_and_Oxidative_Phosphorylation/Properties_of_ATP

Topic 4.2-The Structure and Role of ATP

Tymoczko, J. L., Berg, J. M., & Stryer, L. (2013). Biochemistry: A Short Course, 2nd Edition. New York, NY: W. H. Freeman and Co.

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