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Negative impacts of genetic testing
Negative impacts of genetic testing
Stem cells in the medical field
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There are more than 25,000 genes in the nucleus of each cell in the typical adult human body. The DNA strands in the 10 trillion cells all combined would be long enough to stretch from the earth to the sun more than 100 times (National Human Genome Research Institute). Yet, just one mutation or problem in just one of those genes can cause something as benign as turning brown eyes to blue or something as serious as a deadly case of cancer. The science of genetics is precise and complicated, yet it could very well be the future of human medicine. Stem cell research, genetic counseling, and gene therapy are just some of the more prominent players in the arena that is the science of the human genome. Stem cell therapy is the use of pluripotent stem cells in health care to heal organs and tissues. A cell’s pluripotency is determined by it’s ability to differentiate into other kinds of cells, such as cardiac, skeletal, or nerve (Waldron). Scientists and researchers primarily work with the following types of stem cells: embryonic, mesenchymal, and induced pluripotent. Embryonic was used in some of the first stem cell research due to it being readily available. Early research of embryonic stem cells showed that they was not only very pluripotent, having been used in experiment when they differentiated into blood, cardiac, and skeletal muscle cells. The differentiation of the stem cells into muscle cells was considered to be a milestone as it showed researchers the vast pluripotency of the embryonic stem cells. Skeletal muscles cells were hard to obtain in previous experiments and tests, as they are more complex, and were less understood than cells of simpler tissues, which was significant in showing the diversity of these stem cells. Wh... ... middle of paper ... ...2 Feb. 2014. Web. 4 Mar. 2014. Ormond, D. Ryan, Craig Shannon, Julius Oppenheim, Richard Zeman, Kaushik Das, Raj Murali, and Meena Jhanwar-Uniyal. Stem Cell Therapy and Curcumin Synergistically Enhance Recovery from Spinal Cord Injury. PLOS One. PLOS One, 18 Feb. 2014. Web. 6 Mar. 2014. Ormond, Kelly E. "The Family History and Risk Assessment." National Center for Biotechnology Information. U.S. National Library of Medicine, 11 Nov. 2013. Web. 9 Mar. 2014. Steenhuysen, Julie. "The Dawning of the Age of Genomic Medicine, Finally." Medscape Medical News. Medscape, 10 Mar. 2014. Web. 16 Mar. 2014. Waldron, Patricia. “Stem Cell Creation: Removing the Brakes.” Today's Science.Infobase Learning, Nov. 2013. Web. 16 Mar. 2014. Zimmerman, Ron. "Genetic Code Unlocking Future of Medicine, Craig Venter Says." Medscape Medical News. Medscape, 10 Mar. 2014. Web. 16 Mar. 2014.
The cells unique nature has scientists intrigued to do research with the focus of finding a way that these cells can be used to replace patients’ injured or diseased tissues. Advancement is made to all the three types of stem cells namely embryonic stem cells, adult stem cells in addition to induced pluripotent cells. Embryonic cells are the building blocks of an embryo that is developing, and can develop into almost all body cell types. Somatic cells are found in the body tissues. They renew and regenerate in healthy bodies. The third type which is induced pluripotent is genetically modified embryo cells from skin cells.2 Research on these cells are geared towards saving humanity; a noble course.
In 1990, the first great stride of genetics took place. This was called the Human Genome Project, a large-scale operation that was designed to understand the human genome (genetic structure). Since its commencement, there have been many leaps and bounds that have taken place. For certain genetic issues that we once knew nothing about, we no...
Stem cells are pluripotent cells of the body which are “undifferentiated.” This means that stem cells can ultimately give rise to any type of body tissue. Thus stem cells have the potential to cure a vast number of diseases and physical ailments including Parkinson’s, diabetes, spinal cord injury, and heart disease. Consequently, stem cell research and the development of associated medical applications are of great interest to the scientific and medical community. The area of stem cell research involving human embryonic stem cells is of particular interest in that embryonic stem cells are derived from week-old blastocysts developed from in vitro fertilized eggs. As opposed to adult stem cells, which must undergo a complicated process of de-differen...
Scientists would be able to grow spinal cells from pluripotent stem cells. These cells could possibly repair spinal cord damage. Those afflicted by paralysis, such as Christopher Reeve, could possibly move again. Stem cells could also be used to grow nerve cells, possibly combating Parkinson’s disease or Alzheimer’s. While it will be many years before scientists may actually be able to find a way to combat these diseases, there is a great promise in stem cells.
Stem cell research began in 1956 when Dr. E Donnall Thomas performed the first bone marrow transplant (“Adult stem cells are not more promising,” 2007). Since that time, research has evolved into obtaining cells from a variety of tissues. According to stem cell research professors, Ariff Bongso and Eng Hin Lee (2005), “Stem cells are unspecialized cells in the human body that are capable of becoming cells, each with new specialized functions” (p. 2). Stem cells are in various adult tissues, such as bone marrow, the liver, the epidermis layer of skin, the central nervous system, and eyes. They are also in other sources, such as fetuses, umbilical cords, placentas, embryos, and induced pluripotent stem cells (iPSCs), which are cells from adult tissues that have been reprogrammed to pluripotency. Most stem cells offer multipotent cells, which are sparse...
In Gattaca, the plot focuses on the ethics, the risks, and the emotional impact of genetic testing in the nearby future. The film was released in the 90s; yet in the present, the film does not give the impression of science fiction. Today, genetic testing is prevalent in many aspects of the scientific community. This paper will describe genetic testing, its purpose, diagnostic techniques that use genetic testing, relating Huntington’s disease to genetic testing, and the pros and cons of genetic testing.
This paper focuses on the benefits of stem cell research in the medical and nursing field. New technology is always being created to help us understand the way the human body works, as well as ways to help us improve diseased states in the body. Our bodies have the ability to proliferate or regrow cells when damage is done to the cells. Take for example the skin, when an abrasion or puncture to the skin causes loss of our skin cells, the body has its own way of causing those cells to regrow. The liver, bone marrow, heart, brain, and muscle all have cells that are capable of differentiating into cells of that same type. These are called stem cells, and are a new medical tool that is helping regrow vital organs in our body to help us survive. Stem cells can come from adult cells, or the blastocyst of the embryo. The cells that come from these are undifferentiated, and can be specialized into certain cell types, making them available for many damaged tissues in the body. While using stem cells in the body is a main use, they are also being used to help doctors understand how disease processes start. By culturing these cells in the lab and watching them develop into muscles, nerve cells, or other tissues, researchers are able to see how diseases affect these cells and possibly discover ways to correct these diseases. While researchers have come very far in using stem cells, there are still many controversies to overcome when using these cells.
...hich inherited traits, such as those for genetic disease, can be tracked over generations. Throughout out the course of human development, scientists will continue to find new new ways to help the human race through the discovery of the human gene inside of each of us, its uses, as well as complications, that can help the survival of our species.
“Top Ten Things to Know About Stem Cell Treatments.” Www.closerlookatstemcells.org ISSCR. Web 1 November 2013
Sharp, J., Frame, J., Siegenthaler, M., Nistor, G., Keirstead, H.S. (2010). Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cell Transplants Improve Recovery after Cervical Spinal Cord Injury: Stem Cells, 28, 152 – 163.
Those who favour stem cell research are optimistic about the continued developments in stem cell research will open doors to many breakthrough discoveries in biomedical science. The scientific and ethical questions arise as rapidly as the reaching of milestones in stem cell research. There are two main types of stem cells, namely embryonic stem cells and adult stem cells. Adult stem cells are undifferentiated cells in our body. But they have restricted-range of cells that they can further differentiate. On the contrary, embryonic stem cells have the ability to differentiate into nearly two hundred cell types in the human body, called pluripotency. The process of harvesting embryonic stem cells involves destruction of embryos (Mooney, 2009).
The wide range of prospective uses for stem cells could greatly improve the health and wellbeing of many people. In stem cell treatments, undifferentiated cells are programmed to form specific cells, which can then be transplanted to the afflicted area. Stems cells can possibly treat afflictions including “Alzheimer’s diseases, spinal cord injury, stroke, burns, heart disease, diabetes, osteoarthritis, and rheumatoid arthritis” (“Stem Cell Basics”). Another important use is in drug testing. Drugs can be tested on stem cells that develop into the target tissue before using it on human test subjects, which improves safety. Finally, transplantation of organs created from stem cells could eliminate the need for human...
The age of genetic technology has arrived. Thanks to genetic technological advancements, medical practitioners, with the help of genetic profiling, will be able to better diagnose patients and design individual tailored treatments; doctors will be able to discern which medications and treatments will be most beneficial and produce the fewest adverse side effects. Rationally designed vaccines have been created to provide optimal protection against infections. Food scientists have hopes of genetically altering crops to increase food production, and therefore mitigate global hunger. Law enforcement officers find that their job is made easier through the advancement of forensics; forensics is yet another contribution of genetic technology. Doctors have the ability to identify “high-risk” babies before they are born, which enables them to be better prepared in the delivery room. Additionally, oncologists are able to improve survival rates of cancer patients by administering genetically engineered changes in malignant tumors; these changes result in an increased immune response by the individual. With more than fifty years of research, and billions of dollars, scientists have uncovered methods to improve and prolong human life and the possibilities offered by gene therapy and genetic technology are increasing daily.
Genes are made of DNA – the code of life (Gene Therapy- The Great Debate!). The changes in genes may cause serious problems, which we called genetic disorder. In theory, the only method to cure genetic disorders is gene therapy, which basically means the replacement of genes in order to correct the loss or change in people’s DNA. Although gene therapy gives patients with genetic disorders a permanent cure, it is controversial because it has safety and efficacy problems, and raises ethical issues.
In order to discover the ways for the remedy of diseases, studies in therapeutic approaches have been doing widely and kept increasing at accelerated pace. A lot of research areas had emerged for that purpose including one of the most fascinating and highly active areas at present, stem cells therapies. Due to self-renewal property and differentiation capability of stem cell, it becomes a new hope in modern treatment.